Fibroin
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Fibroin
Fibroin is an insoluble protein present in silk produced by numerous insects, such as the larvae of ''Bombyx mori'', and other moth genera such as ''Antheraea'', ''Cricula trifenestrata, Cricula'', ''Samia (moth), Samia'' and ''Gonometa''. Silk in its raw state consists of two main proteins, sericin and fibroin, with a glue-like layer of sericin coating two singular filaments of fibroin called brins. Silk fibroin is considered a β-keratin related to proteins that form hair, skin, nails and connective tissues. The silk worm produces fibroin with three chains, the light, heavy, and the glycoprotein P25. The heavy and light chains are linked by a disulphide bond, and P25 associates with disulphide-linked heavy and light chains by noncovalent interactions. P25 plays an important role in maintaining integrity of the complex. The heavy fibroin protein consists of layers of antiparallel beta sheets. Its primary structure mainly consists of the recurrent amino acid sequence (Glyci ...
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Silk Fibroin Primary Structure
Silk is a natural protein fiber, some forms of which can be woven into textiles. The protein fiber of silk is composed mainly of fibroin and is most commonly produced by certain insect larvae to form cocoons. The best-known silk is obtained from the cocoons of the larvae of the mulberry silkworm ''Bombyx mori'' reared in captivity (sericulture). The shimmering appearance of silk is due to the triangular prism-like structure of the silk fibre, which allows silk cloth to refract incoming light at different angles, thus producing different colors. Harvested silk is produced by several insects; but, generally, only the silk of various moth caterpillars has been used for textile manufacturing. There has been some research into other types of silk, which differ at the molecular level. Silk is mainly produced by the larvae of insects undergoing complete metamorphosis, but some insects, such as webspinners and raspy crickets, produce silk throughout their lives. Silk production al ...
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Silk
Silk is a natural fiber, natural protein fiber, some forms of which can be weaving, woven into textiles. The protein fiber of silk is composed mainly of fibroin and is most commonly produced by certain insect larvae to form cocoon (silk), cocoons. The best-known silk is obtained from the cocoons of the larvae of the mulberry silkworm ''Bombyx mori'' reared in captivity (sericulture). The shimmering appearance of silk is due to the triangular Prism (optics), prism-like structure of the silk fibre, which allows silk cloth to refract incoming light at different angles, thus producing different colors. Harvested silk is produced by several insects; but, generally, only the silk of various moth caterpillars has been used for textile manufacturing. There has been some research into other types of silk, which differ at the molecular level. Silk is mainly produced by the larvae of insects undergoing holometabolism, complete metamorphosis, but some insects, such as webspinners and Gr ...
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Sericin
Sericin is a protein created by ''Bombyx mori'' (silkworms) in the production of silk. Silk is a fibre produced by the silkworm in production of its cocoon. It consists mainly of two proteins, fibroin and sericin. Silk consists of 70–80% fibroin and 20–30% sericin; fibroin being the structural center of the silk, and sericin being the gum coating the fibres and allowing them to stick to each other. Structure Sericin is composed of 18 different amino acids, of which 32% is serine. The secondary structure is usually a random coil, but it can also be easily converted into a β-sheet conformation, via repeated moisture absorption and mechanical stretching. The serine hydrogen bonds give its glue-like quality. The genes encoding sericin proteins have been sequenced. Its C-terminal part contains many serine-rich repeats. Using gamma ray examination, it was determined that sericin fibers are composed typically of three layers, all with fibers running in different patterns of d ...
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Keratin
Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. It is the key structural material making up Scale (anatomy), scales, hair, Nail (anatomy), nails, feathers, horn (anatomy), horns, claws, Hoof, hooves, and the outer layer of skin in vertebrates. Keratin also protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong mineralization (biology), unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals. Excessive keratinization participate in fortification of certain tissues such as in horns of cattle and rhinos, and armadillos' osteoderm. The only other biology, biological matter known to approximate the toughness of keratinized tissue is chitin. Keratin comes in two types: the primitive, softer forms found in all vertebrates and the harder, derived forms fou ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ...
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Serine
Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α- amino group (which is in the protonated − form under biological conditions), a carboxyl group (which is in the deprotonated − form under biological conditions), and a side chain consisting of a hydroxymethyl group, classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid. It is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC. Occurrence This compound is one of the proteinogenic amino acids. Only the L- stereoisomer appears naturally in proteins. It is not essential to the human diet, since it is synthesized in the body from other metabolites, including glycine. Serine was first obtained from silk protein, a particularly rich source, in 1865 by Emil Cramer. Its name is derived from the Latin for silk, '' sericum''. Serine's structure was established in ...
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Polylactic Acid
Polylactic acid, also known as poly(lactic acid) or polylactide (PLA), is a plastic material. As a thermoplastic polyester (or polyhydroxyalkanoate) it has the backbone formula or . PLA is formally obtained by condensation of lactic acid with loss of water (hence its name). It can also be prepared by ring-opening polymerization of lactide , the cyclic dimer of the basic repeating unit. Often PLA is blended with other polymers. PLA can be biodegradable or long-lasting, depending on the manufacturing process, additives and copolymers. PLA has become a popular material due to it being economically produced from renewable resources and the possibility to use it for compostable products. In 2022, PLA had the highest consumption volume of any bioplastic of the world, with a share of ca. 26 % of total bioplastic demand. Although its production is growing, PLA is still not as important as traditional commodity polymers like PET or PVC. Its widespread application has been hin ...
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Amycolatopsis
''Amycolatopsis'' is a genus of high GC-content bacteria within the family Pseudonocardiaceae. The genus is known for producing many types of antibiotics, including *Epoxyquinomicin, related to ''Amycolatopsis sulphurea'', are a class of weak antibiotic and anti-inflammatory agent. *Vancomycin, obtained from ''Amycolatopsis orientalis'', is being used for infections resistant to other antibiotics. *Ristocetin, made by ''Amycolatopsis lurida'', was an antibiotic but ceased to apply due to adverse effects of platelet agglutination. Now it is used to assay von Willebrand disease. Degradation of bio-polymers Several bacteria from the genus ''Amycolatopsis'' are able to enzymatically hydrolyze the ester bonds of poly-lactic acid (Polylactic acid, PLA) films in aquatic medium. So far, it is one of the few known bacteria able to biodegrade the bioplastic outside compost facilities in a relatively short period of time. Species ''Amycolatopsis'' comprises the following species: * ''Am ...
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Textile
Textile is an Hyponymy and hypernymy, umbrella term that includes various Fiber, fiber-based materials, including fibers, yarns, Staple (textiles)#Filament fiber, filaments, Thread (yarn), threads, and different types of #Fabric, fabric. At first, the word "textiles" only referred to woven fabrics. However, weaving is not the only manufacturing method, and many other methods were later developed to form textile structures based on their intended use. Knitting and Nonwoven, non-woven are other popular types of fabric manufacturing. In the contemporary world, textiles satisfy the material needs for versatile applications, from simple daily clothing to Bulletproof vest, bulletproof jackets, spacesuits, and Medical gown, doctor's gowns. Textiles are divided into two groups: consumer textiles for domestic purposes and technical textiles. In consumer textiles, Aesthetics (textile), aesthetics and Textile performance#Comfort, comfort are the most important factors, while in techn ...
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Biomedicine
Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)Biomedicine
" NCI Dictionary of Cancer Medicine. .
is a branch of that applies biological and physiological principles to . Biomedicine stresses standardized, evidence-based treatment validated through biological research, with treatment administered via formally tr ...
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