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Cataplexy
Cataplexy is a sudden and transient episode of muscle weakness accompanied by full conscious awareness, typically triggered by emotions such as laughing, crying, or terror. Cataplexy is the first symptom to appear in about 10% of cases of narcolepsy, caused by an autoimmune destruction of hypothalamic neurons that produce the neuropeptide hypocretin (also called orexin), which regulates arousal and has a role in stabilization of the transition between wake and sleep states. Cataplexy without narcolepsy is rare and the cause is unknown. The term cataplexy originates from the Greek κατά (''kata'', meaning "down"), and πλῆξις (''plēxis'', meaning "strike") and it was first used around 1880 in German physiology literature to describe the phenomenon of tonic immobility also known as " playing possum" (in reference to the opossum's behavior of feigning death when threatened). In the same year the French neuropsychiatrist Jean-Baptiste Gélineau coined the term 'narcol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Narcolepsy
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. The symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. People with narcolepsy typically have poor quality of sleep. There are two recognized forms of narcolepsy, narcolepsy type 1 and type 2. Narcolepsy type 1 (NT1) can be clinically characterized by symptoms of EDS and cataplexy, and/or will have cerebrospinal fluid (CSF) orexin levels of less than 110 pg/ml. Cataplexy are transient episodes of aberrant tone, most typically loss of tone, that can be associated with strong emotion. In pediatric-onset narcolepsy, active motor phenomena are not uncommon. Cataplexy may be mistaken for syncope, tics, or seizures. Narcolepsy type 2 (NT2) does not have features of cataplexy, and CSF orexin levels are normal. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Hypocretin
Orexin (), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. It exists in the forms of orexin-A and orexin-B. The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells that produce it.Stanford Center for NarcolepsFAQ(retrieved 27-Mar-2012) There are 50,000–80,000 orexin-producing neurons in the human brain, located predominantly in the perifornical area and lateral hypothalamus. They project widely throughout the central nervous system, regulating wakefulness, feeding, and other behaviours. There are two types of orexin peptide and two types of orexin receptor. Orexin was discovered in 1998 almost simultaneously by two independent groups of researchers working on the rat brain. One group named it orexin, from ''orexis,'' meaning "appetite" in Greek; the other group named it hypocr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Bob Beamon
Robert Beamon (born August 29, 1946) is an American former track and field athlete, best known for his world record in the long jump at the Mexico City Olympics in 1968. By jumping , he broke the existing record by a margin of and his world record stood for almost 23 years until it was broken in 1991 by Mike Powell. The jump is still the Olympic record and the second-longest in history unassisted by wind. Early life Robert Beamon was born in South Jamaica, Queens, New York, to Naomi Brown Beamon and grew up in the New York Housing Authority's Jamaica Houses. When Beamon was eight months old, his mother died from tuberculosis, and, as a result of his stepfather's incarceration, he was placed into the care of his maternal grandmother, Bessie. When Beamon was attending Jamaica High School, Larry Ellis, a renowned track coach, discovered him. Beamon later became part of the All-American track and field team. Beamon began his college career at North Carolina Agricultural and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Laughter
Laughter is a pleasant physical reaction and emotion consisting usually of rhythmical, usually audible contractions of the diaphragm and other parts of the respiratory system. It is a response to certain external or internal stimuli. Laughter can rise from such activities as being tickled, or from humorous stories, imagery, videos or thoughts. Most commonly, it is considered an auditory expression of a number of positive emotional states, such as joy, mirth, happiness or relief. On some occasions, however, it may be caused by contrary emotional states such as embarrassment, surprise, or confusion such as nervous laughter or courtesy laugh. Age, gender, education, language and culture are all indicators as to whether a person will experience laughter in a given situation. Other than humans, some other species of primate (chimpanzees, gorillas and orangutans) show laughter-like vocalizations in response to physical contact such as wrestling, play chasing or tickling. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Rapid Eye Movement Sleep
Rapid eye movement sleep (REM sleep or REMS) is a unique phase of sleep in mammals (including humans) and birds, characterized by random rapid movement of the eyes, accompanied by low muscle tone throughout the body, and the propensity of the sleeper to dream vividly. The core body and brain temperatures increase during REM sleep and skin temperature decreases to lowest values. The REM phase is also known as paradoxical sleep (PS) and sometimes desynchronized sleep or dreamy sleep, because of physiological similarities to waking states including rapid, low-voltage desynchronized brain waves. Electrical and chemical activity regulating this phase seem to originate in the brain stem, and is characterized most notably by an abundance of the neurotransmitter acetylcholine, combined with a nearly complete absence of monoamine neurotransmitters histamine, serotonin and norepinephrine. Experiences of REM sleep are not transferred to permanent memory due to absence of norepinephrine. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Neurology
Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the Human brain, brain, the spinal cord and the peripheral nervous system , peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Hypnagogic Hallucination
Hypnagogia is the transitional state from wakefulness to sleep, also defined as the waning state of consciousness during the onset of sleep. Its corresponding state is '' hypnopompia'' sleep to wakefulness. Mental phenomena that may occur during this "threshold consciousness" include hallucinations, lucid dreaming, and sleep paralysis. Etymology In 1848, Alfred Maury introduced the term "hypnagogic" from the Greek words ύπνος (“hypnos”), meaning “sleep”, and αγωγός (“agōgos”), meaning “conductor” or “leader”. Later, in 1904, Frederic Myers coined the term "hypnopompic," with its word-ending originating from the Greek word "pompos," meaning "sender." Definitions The word ''hypnagogia'' is sometimes used in a restricted sense to refer to the onset of sleep, and contrasted with '' hypnopompia'', Frederic Myers's term for waking up. However, ''hypnagogia'' is also regularly employed in a more general sense that covers both falling asleep and waki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Astrocytoma
Astrocytoma is a type of brain tumor. Astrocytomas (also astrocytomata) originate from a specific kind of star-shaped glial cell in the cerebrum called an astrocyte. This type of tumor does not usually spread outside the brain and spinal cord, and it does not usually affect other organs. After glioblastomas, astrocytomas are the second most common glioma and can occur in most parts of the brain and occasionally in the spinal cord. Within the astrocytomas, two broad classes are recognized in literature, those with: * Narrow zones of infiltration (mostly noninvasive tumors; e.g., pilocytic astrocytoma, subependymal giant cell astrocytoma, pleomorphic xanthoastrocytoma), that often are clearly outlined on diagnostic images * Diffuse zones of infiltration (e.g., high-grade astrocytoma), that share various features, including the ability to arise at any location in the central nervous system, but with a preference for the cerebral hemispheres; they occur usually in adults, and have an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Brainstem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory system, respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Simplified Brain Motor Circuit
Simplification, Simplify, or Simplified may refer to: Mathematics Simplification is the process of replacing a mathematical expression by an equivalent one that is simpler (usually shorter), according to a well-founded ordering. Examples include: * Simplification of algebraic expressions, in computer algebra * Simplification of boolean expressions i.e. logic optimization * Simplification by conjunction elimination in inference in logic yields a simpler, but generally non-equivalent formula * Simplification of fractions Science * Approximations simplify a more detailed or difficult to use process or model Linguistics * Simplification of Chinese characters * Simplified English (other) * Text simplification Music * ''Simplify'', a 1999 album by Ryan Shupe & the RubberBand * Simplified (band), a 2002 rock band from Charlotte, North Carolina * ''Simplified'' (album), a 2005 album by Simply Red * "Simplify", a 2008 song by Sanguine * "Simplify", a 2018 song by Young the G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Long Jump
The long jump is a track and field event in which athletes combine speed, strength and agility in an attempt to leap as far as possible from a takeoff point. Along with the triple jump, the two events that measure jumping for distance as a group are referred to as the "horizontal jumps". This event has a history in the ancient Olympic Games and has been a modern Olympic event for men since the first Olympics in 1896 and for women since 1948. Rules At the elite level, competitors run down a runway (usually coated with the same All-weather running track, rubberized surface as running tracks, crumb rubber or vulcanized rubber, known generally as an all-weather track) and jump as far as they can from a wooden or synthetic board, 20 centimetres or 8 inches wide, that is built flush with the runway, into a pit filled with soft damp sand. If the competitor starts the leap with any part of the foot past the foul line, the jump is declared a foul and no distance is recorded. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
1968 Summer Olympics
The 1968 Summer Olympics (), officially known as the Games of the XIX Olympiad () and officially branded as Mexico 1968 (), were an international multi-sport event held from 12 to 27 October 1968, in Mexico City, Mexico. These were the first Olympic Games to be staged in Latin America, the first to be staged in a Hispanophone, Spanish-speaking country, and the first to be staged in the Global South. Consequently, these games also marked the first time that there would be a gap of two Olympic Games not to be held in Europe. They were also the first Games to use an All-weather running track, all-weather (smooth) track for track and field events instead of the traditional cinder track, as well as the first example of the Olympics exclusively using electronic timekeeping equipment. The 1968 Games were the third to be held in the last quarter of the year, after the 1956 Summer Olympics, 1956 Games in Melbourne and the 1964 Summer Olympics, 1964 Games in Tokyo. The Mexican Movement of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
