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XY Sex-determination System
The XY sex-determination system is a sex-determination system present in many mammals (including humans), some insects (''Drosophila''), some snakes, some fish (guppy, guppies), and some plants (''Ginkgo'' tree). In this system, the sex of an individual usually is determined by a pair of Allosome, sex chromosomes. Typically, females have two of the same kind of sex chromosome (XX), and are called the homogametic sex. Males typically have two different kinds of sex chromosomes (XY), and are called the heterogametic sex. In humans, the presence of the Y chromosome is responsible for triggering male development; in the absence of the Y chromosome, the fetus will undergo female development. In most species with XY sex determination, an organism must have at least one X chromosome in order to survive. The XY system contrasts in several ways with the ZW sex-determination system found in birds, some insects, many reptiles, and various other animals, in which the heterogametic sex is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila XY Sex-determination
''Drosophila'' (), from Ancient Greek δρόσος (''drósos''), meaning "dew", and φίλος (''phílos''), meaning "loving", is a genus of fly, belonging to the family (biology), family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''Drosophila melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most important of these proteins are the histones. Aided by chaperone proteins, the histones bind to and condense the DNA molecule to maintain its integrity. These eukaryotic chromosomes display a complex three-dimensional structure that has a significant role in transcriptional regulation. Normally, chromosomes are visible under a light microscope only during the metaphase of cell division, where all chromosomes are aligned in the center of the cell in their condensed form. Before this stage occurs, each chromosome is duplicated ( S phase), and the two copies are joined by a centromere—resulting in either an X-shaped structure if the centromere is located equatorially, or a two-armed structure if the centromere is located distally; the jo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monotreme
Monotremes () are mammals of the order Monotremata. They are the only group of living mammals that lay eggs, rather than bearing live young. The extant monotreme species are the platypus and the four species of echidnas. Monotremes are typified by structural differences in their brains, jaws, digestive tract, reproductive tract, and other body parts, compared to the more common mammalian types. Although they are different from other living mammals in that they lay eggs, female monotremes are like other mammals in that they nurse their young with milk. Monotremes have been considered by some authors to be members of Australosphenida, a clade that contains extinct mammals from the Jurassic and Cretaceous of Madagascar, South America, and Australia, but this categorization is disputed and their taxonomy is under debate. All extant species of monotremes are indigenous to Australia and New Guinea, although they were also present during the Late Cretaceous and Paleocene epochs in s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Platypus
The platypus (''Ornithorhynchus anatinus''), sometimes referred to as the duck-billed platypus, is a semiaquatic, egg-laying mammal endemic to eastern Australia, including Tasmania. The platypus is the sole living representative or monotypic taxon of its family Ornithorhynchidae and genus ''Ornithorhynchus'', though a number of related species appear in the fossil record. Together with the four species of echidna, it is one of the five extant species of monotremes, mammals that lay eggs instead of giving birth to live young. Like other monotremes, the platypus has a sense of electrolocation, which it uses to detect prey in cloudy water. It is one of the few species of venomous mammals, as the male platypus has a spur on the hind foot that delivers an extremely painful venom. The unusual appearance of this egg-laying, duck-billed, beaver-tailed, otter-footed mammal at first baffled European naturalists. In 1799, the first scientists to examine a preserved platypus bod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theria
Theria ( or ; ) is a scientific classification, subclass of mammals amongst the Theriiformes. Theria includes the eutherians (including the Placentalia, placental mammals) and the metatherians (including the marsupials) but excludes the egg-laying monotremes and various extinct mammals evolving prior to the common ancestor of placentals and marsupials. Characteristics Therians give birth to live young without a shelled egg (biology), egg. This is possible thanks to key proteins called Syncytin-1, syncytins which allow exchanges between the mother and its offspring through a placenta, even Marsupial#Reproductive system, rudimental ones such as in marsupials. Genetic studies have suggested a viral origin of syncytins through the Endogenous retrovirus, endogenization process. The marsupials and the placentals evolved from a common therian ancestor that gave live birth by suppressing the mother's immune system. While the marsupials continued to give birth to an underdeveloped fe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wolffian Duct
The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that plays a critical role in the formation of male reproductive organs. The duct is named after Caspar Friedrich Wolff, a German physiologist and embryologist who first described it in 1759. During embryonic development, the mesonephric ducts form as a part of the urogenital system. Structure The mesonephric duct connects the primitive kidney, the '' mesonephros'', to the cloaca. It also serves as the primordium for male urogenital structures including the epididymides, vasa deferentia, and seminal vesicles. Development In both males and females, the mesonephric ducts develop into the trigone of urinary bladder, a part of the bladder wall, but the sexes differentiate in other ways during development of the urinary and reproduc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Testosterone
Testosterone is the primary male sex hormone and androgen in Male, males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of androgenic hair, body hair. It is associated with increased aggression, sex drive, Dominance hierarchy, dominance, courtship display, and a wide range of behavioral characteristics. In addition, testosterone in both sexes is involved in health and well-being, where it has a significant effect on overall mood, cognition, social and sexual behavior, metabolism and energy output, the cardiovascular system, and in the prevention of osteoporosis. Insufficient levels of testosterone in men may lead to abnormalities including frailty, accumulation of adipose fat tissue within the body, anxiety and depression, sexual performance issues, and bone loss. Excessiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred Jost
Alfred Jost (1916–1991) was a French endocrinologist, and an early researcher in the field of fetal endocrinology. He is known for his discovery of the Müllerian inhibitor, now called anti-Müllerian hormone (AMH) or Müllerian inhibiting substance (MIS). His research demonstrated how hormones affect the development of male and female sex characteristics. Career Jost was a professor at the University of Paris, and was head of the Department of Comparative Physiology there in 1972. Jost was known for applying surgical methods to fetal endocrinology. He also taught many pre-doctoral students. Research During the 1950s and 1960s Jost studied the mechanism of somatic sex differentiation; his research showed that male characteristics must be imposed on the fetus by the testicular hormones testosterone and AMH, and that in the absence or inactivity of these hormones, the fetus becomes phenotypically female.However, this has been discredited by recent studies. Jost also stud ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trisomy X
Trisomy X, also known as triple X syndrome and characterized by the karyotype 47,XXX, is a chromosome disorder in which a female has an extra copy of the X chromosome. It is relatively common and occurs in 1 in 1,000 females, but is rarely diagnosed; fewer than 10% of those with the condition know they have it. Those who have symptoms can have learning disabilities, mild dysmorphic features such as hypertelorism (wide-spaced eyes) and clinodactyly (incurved little fingers), early menopause, and increased height. As the symptoms of trisomy X are often not serious enough to prompt a karyotype test, many cases of trisomy X are diagnosed before birth via prenatal screening tests such as amniocentesis. Most females with trisomy X live normal lives, although their socioeconomic status is reduced compared to the general population. Trisomy X occurs via a process called nondisjunction, in which normal cell division is interrupted and produces gametes with too many or too few chromosomes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Turner Syndrome
Turner syndrome (TS), commonly known as 45,X, or 45,X0,Also written as 45,XO. is a chromosomal disorder in which cells of females have only one X chromosome instead of two, or are partially missing an X chromosome (sex chromosome monosomy) leading to the complete or partial deletion of the pseudoautosomal regions (PAR1, PAR2) in the affected X chromosome. Typically, people have two sex chromosomes (XX for females or XY for males). The chromosomal abnormality is often present in just some cells, in which case it is known as Turner syndrome with mosaicism. 45,X0 with mosaicism can occur in males or females, but Turner syndrome without mosaicism only occurs in females. Signs and symptoms vary among those affected but often include additional skin folds on the neck, arched palate, low-set ears, low hairline at the nape of the neck, short stature, and lymphedema of the hands and feet. Those affected do not normally develop menstrual periods or mammary glands without hormone trea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
XYY Syndrome
XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. There are usually few symptoms. These may include being taller than average and an increased risk of learning disabilities. The person is generally otherwise normal, including typical rates of fertility. The condition is generally not inherited but rather occurs as a result of a random event during sperm development. Diagnosis is by a chromosomal analysis, but most of those affected are not diagnosed within their lifetime. There are 47 chromosomes, instead of the usual 46, giving a 47,XYY karyotype. Treatment may include speech therapy or extra help with schoolwork, and outcomes are generally positive. The condition occurs in about 1 in 1,000 male births. Many people with the condition are unaware that they have it. The condition was first described in 1961. Signs and symptoms Physical traits People with the 47,XYY karyotype have an increased growth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Klinefelter Syndrome
Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly where a male has an extra X chromosome. These complications commonly include infertility and small, poorly functioning testicles (if present). These symptoms are often noticed only at puberty, although this is one of the most common chromosomal disorders. The birth prevalence of KS in the State of Victoria, Australia was estimated to be 223 per 100,000 males. It is named after American endocrinologist Harry Klinefelter, who identified the condition in the 1940s, along with his colleagues at Massachusetts General Hospital. The syndrome is defined by the presence of at least one extra X chromosome in addition to a Y chromosome, yielding a total of 47 or more chromosomes rather than the usual 46. Klinefelter syndrome occurs randomly. The extra X chromosome comes from the father and mother nearly equally. An older mother may have a slightly increased risk of a child with KS. The syndrome is diagnosed by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
