Walery Jaworski
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Walery Jaworski
Walery Jaworski (born March 20, 1849 in Florynka – died July 17, 1924 in Kraków) was one of the pioneers of gastroenterology in Poland. In 1899 he described bacteria living in the human stomach that he named ''Vibrio rugula''. He speculated that they were responsible for stomach ulcers, gastric cancer and achylia. It was one of the first observations of Helicobacter pylori. He published those findings in 1899 in a book titled ''Podręcznik chorób żołądka'' (''Handbook of Gastric Diseases'') but it was available only in Polish and went unnoticed. His findings were independently confirmed by Robin Warren and Barry Marshall, who received the Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ... in 2005. References 1849 births 1924 deaths Polish gastroentero ...
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Walery Jaworski
Walery Jaworski (born March 20, 1849 in Florynka – died July 17, 1924 in Kraków) was one of the pioneers of gastroenterology in Poland. In 1899 he described bacteria living in the human stomach that he named ''Vibrio rugula''. He speculated that they were responsible for stomach ulcers, gastric cancer and achylia. It was one of the first observations of Helicobacter pylori. He published those findings in 1899 in a book titled ''Podręcznik chorób żołądka'' (''Handbook of Gastric Diseases'') but it was available only in Polish and went unnoticed. His findings were independently confirmed by Robin Warren and Barry Marshall, who received the Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ... in 2005. References 1849 births 1924 deaths Polish gastroentero ...
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Florynka
Florynka ( rue, Фльоринка, ''Fliorynka'') is a village in southern Poland, in the commune of Grybów, Nowy Sącz County, Lesser Poland Voivodeship. It lies approximately south of Grybów, east of Nowy Sącz, and south-east of the regional capital Kraków. History * 1785 – 745 Greek Catholics, 10 Roman Catholics, the village lands comprised 20.22 km2 * 1840 – 992 Greek Catholics * 1859 – 1205 Greek Catholics * 1879 – 928 Greek Catholics * 1899 – 1150 Greek Catholics * 1926 – 1108 Greek Catholics * 1936 – 228 Greek Catholics – village switched to Orthodoxy, afterwards there were 1246 Orthodox, 57 Roman Catholics and 37 Jews Florynka was the place of origin of the short-lived Lemko-Rusyn Republic from 1918 to 1920. The village was incorporated into the Lemko Apostolic Administration in 1934. The Lemko inhabitants of the village were removed in Operation Vistula in 1947, and scattered to 30 different villages in 6 counties. Church The Saint Michae ...
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Kraków
Kraków (), or Cracow, is the second-largest and one of the oldest cities in Poland. Situated on the Vistula River in Lesser Poland Voivodeship, the city dates back to the seventh century. Kraków was the official capital of Poland until 1596 and has traditionally been one of the leading centres of Polish academic, economic, cultural and artistic life. Cited as one of Europe's most beautiful cities, its Old Town with Wawel Royal Castle was declared a UNESCO World Heritage Site in 1978, one of the first 12 sites granted the status. The city has grown from a Stone Age settlement to Poland's second-most-important city. It began as a hamlet on Wawel Hill and was reported by Ibrahim Ibn Yakoub, a merchant from Cordoba, as a busy trading centre of Central Europe in 985. With the establishment of new universities and cultural venues at the emergence of the Second Polish Republic in 1918 and throughout the 20th century, Kraków reaffirmed its role as a major national academic and ...
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Gastroenterology
Gastroenterology (from the Greek gastḗr- “belly”, -énteron “intestine”, and -logía "study of") is the branch of medicine focused on the digestive system and its disorders. The digestive system consists of the gastrointestinal tract, sometimes referred to as the ''GI tract,'' which includes the esophagus, stomach, small intestine and large intestine as well as the accessory organs of digestion which includes the pancreas, gallbladder, and liver. The digestive system functions to move material through the GI tract via peristalsis, break down that material via digestion, absorb nutrients for use throughout the body, and remove waste from the body via defecation. Physicians who specialize in the medical specialty of gastroenterology are called gastroenterologists or sometimes ''GI doctors''. Some of the most common conditions managed by gastroenterologists include gastroesophageal reflux disease, gastrointestinal bleeding, irritable bowel syndrome, irritable bow ...
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Poland
Poland, officially the Republic of Poland, is a country in Central Europe. It is divided into 16 administrative provinces called voivodeships, covering an area of . Poland has a population of over 38 million and is the fifth-most populous member state of the European Union. Warsaw is the nation's capital and largest metropolis. Other major cities include Kraków, Wrocław, Łódź, Poznań, Gdańsk, and Szczecin. Poland has a temperate transitional climate and its territory traverses the Central European Plain, extending from Baltic Sea in the north to Sudeten and Carpathian Mountains in the south. The longest Polish river is the Vistula, and Poland's highest point is Mount Rysy, situated in the Tatra mountain range of the Carpathians. The country is bordered by Lithuania and Russia to the northeast, Belarus and Ukraine to the east, Slovakia and the Czech Republic to the south, and Germany to the west. It also shares maritime boundaries with Denmark a ...
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Stomach Ulcers
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases. Common causes include the bacteria '' Helicobacter pylori'' and non-steroidal anti-inflammatory drugs (NSAIDs). Other, less common causes include tobacco smoking, stress as a result of other serious health conditions, Behçet's ...
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Gastric Cancer
Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. Lymphomas and mesenchymal tumors may also develop in the stomach. Early symptoms may include heartburn, upper abdominal pain, nausea, and loss of appetite. Later signs and symptoms may include weight loss, yellowing of the skin and whites of the eyes, vomiting, difficulty swallowing, and blood in the stool, among others. The cancer may spread from the stomach to other parts of the body, particularly the liver, lungs, bones, lining of the abdomen, and lymph nodes. The most common cause is infection by the bacterium ''Helicobacter pylori'', which accounts for more than 60% of cases. Certain types of ''H. pylori'' have greater risks than others. Smoking, dietary factors such as pickled vegetables and obesity are other risk factors. About 10% ...
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Achylia
Achlorhydria and hypochlorhydria refer to states where the production of hydrochloric acid in gastric secretions of the stomach and other digestive organs is absent or low, respectively. It is associated with various other medical problems. Signs and symptoms Irrespective of the cause, achlorhydria can result as known complications of bacterial overgrowth and intestinal metaplasia and symptoms are often consistent with those diseases: *gastroesophageal reflux disease *abdominal discomfort *early satiety *weight loss *diarrhea *constipation *abdominal bloating *anemia *stomach infection *malabsorption of food * carcinoma of stomach Since acidic pH facilitates the absorption of iron, achlorhydric patients often develop iron deficiency anemia. Acidic environment of stomach helps conversion of pepsinogen into pepsin, which is highly important in digesting the protein into smaller components, such as a complex protein into simple peptides and amino acids inside the stomach, which are ...
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Helicobacter Pylori
''Helicobacter pylori'', previously known as ''Campylobacter pylori'', is a gram-negative, microaerophilic, spiral (helical) bacterium usually found in the stomach. Its helical shape (from which the genus name, helicobacter, derives) is thought to have evolved in order to penetrate the mucoid lining of the stomach and thereby establish infection. The bacterium was first identified in 1982 by the Australian doctors Barry Marshall and Robin Warren. ''H. pylori'' has been associated with cancer of the mucosa-associated lymphoid tissue in the stomach, esophagus, colon, rectum, or tissues around the eye (termed extranodal marginal zone B-cell lymphoma of the cited organ), and of lymphoid tissue in the stomach (termed diffuse large B-cell lymphoma). ''H. pylori'' infection usually has no symptoms but sometimes causes gastritis (stomach inflammation) or ulcers of the stomach or first part of the small intestine. The infection is also associated with the development of ...
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Robin Warren
John Robin Warren (born 11 June 1937, in Adelaide) is an Australian pathologist, Nobel Laureate and researcher who is credited with the 1979 re-discovery of the bacterium ''Helicobacter pylori'', together with Barry Marshall. The duo proved to the medical community that the bacterium ''Helicobacter pylori (H. pylori)'' is the cause of most peptic ulcers. Early life and education Warren received his M.B.B.S. degree from the University of Adelaide, having completed his high school education at St Peter's College, Adelaide. Career Warren trained at the Royal Adelaide Hospital and became Registrar in Clinical Pathology at the Institute of Medical and Veterinary Science (IMVS), where he worked in laboratory haematology which generated his interest in pathology. In 1963, Warren was appointed Honorary Clinical Assistant in Pathology and Honorary Registrar in Haematology at Royal Adelaide Hospital. Subsequently, he lectured in pathology at Adelaide University, then took up the p ...
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Barry Marshall
Barry James Marshall (born 30 September 1951) is an Australian physician, Nobel Prize Laureate in Physiology or Medicine, Professor of Clinical Microbiology and Co-Director of the Marshall Centre at the University of Western Australia. Marshall and Robin Warren showed that the bacterium '' Helicobacter pylori'' (''H. pylori'') plays a major role in causing many peptic ulcers, challenging decades of medical doctrine holding that ulcers were caused primarily by stress, spicy foods, and too much acid. This discovery has allowed for a breakthrough in understanding a causative link between '' Helicobacter pylori'' infection and stomach cancer. Education and early life Marshall was born in Kalgoorlie, Western Australia and lived in Kalgoorlie and Carnarvon until moving to Perth at the age of eight. His father held various jobs, and his mother was a nurse. He is the eldest of four siblings. He attended Newman College for his secondary education and the University of Western Au ...
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Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Ec ...
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