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Vinod Scaria
Dr Vinod Scaria FRSB, FRSPH (born 9 March 1981) is an Indian biologist, medical researcher pioneering in Precision Medicine and Clinical Genomics in India. He is best known for sequencing the first Indian genome. He was also instrumental in the sequencing of The first Sri Lankan Genome, analysis of the first Malaysian Genome sequencing and analysis of the Wild-type strain of Zebrafish and the IndiGen programme on Genomics for Public Health in India. He is presently the Chief Data Officer at Karkinos Healthcare and an adjunct professor at the IIT Kanpur. He was previously a senior scientist at CSIR Institute of Genomics and Integrative Biology and an adjunct faculty at Indraprastha Institute of Information Technology, Delhi. He along with his colleague and collaborator Sridhar Sivasuubu are widely regarded as the pioneers in the area of clinical genomics in India. They are also the co-founders of the Genomics for Understanding Rare Diseases India Alliance Network (GUaRDIAN) a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mbinga
Mbinga is a town and ward in the Ruvuma Region of southwestern Tanzania. It is located along the A19 road The A19 is a major road in England running approximately parallel to and east of the A1 road (Great Britain), A1 road. Although the two roads meet at the northern end of the A19, the two roads originally met at the southern end of the A19 in ..., to the northeast of Ndengo and southwest of Kigonsera. References Wards of Ruvuma Region {{Ruvuma-geo-stub de:Mbinga sw:Wilaya ya Mbinga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IIT Kanpur
The Indian Institute of Technology Kanpur (IIT- Kanpur or IIT-K) is a public institute of technology located in Kanpur, Uttar Pradesh, India. As an Indian Institute of Technology (IIT), it was declared an Institute of National Importance by the Government of India under the Institutes of Technology Act. IIT Kanpur has been occasionally ranked among the best academic institutions in India. As of January 2025, at least 17 Padma Shri, 4 Padma Bhushan, 1 Padma Vibhushan, and 33 Shanti Swarup Bhatnagar Prize recipients have been affiliated with IIT Kanpur as alumni or faculty members. History IIT Kanpur was established by an Act of Parliament in 1960 by the Government of India. The institute was started in December 1959 in a room in the canteen building of the Harcourt Butler Technological University at Agricultural Gardens in Kanpur. In 1963, the institute moved to its present location, on the Grand Trunk Road near Kalyanpur locality in Kanpur district. The campus, which is p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Translational Medicine
The ''Journal of Translational Medicine'' is a peer-reviewed open-access medical journal published by BioMed Central since 2003. The editor-in-chief is Francesco Marincola. According to the ''Journal Citation Reports'', the journal had a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 8.440. References External links * General medical journals Creative Commons Attribution-licensed journals BioMed Central academic journals Academic journals established in 2003 English-language journals Translational medicine {{General-medical-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PeerJ
''PeerJ'' is an open access peer-reviewed scientific mega journal covering research in the biological and medical sciences. It officially launched in June 2012, started accepting submissions on December 3, 2012, and published its first articles on February 12, 2013. In 2024, the firm was acquired by traditional research publisher Taylor & Francis. Overview PeerJ was originally published by a company of the same name that was co-founded by CEO Jason Hoyt (formerly at Mendeley) and publisher Peter Binfield (formerly at '' PLOS One''), with initial financial backing of US$950,000 from O'Reilly Media's O'Reilly AlphaTech Ventures, and later funding from Sage Publishing. The firm is a member of CrossRef, CLOCKSS, ORCID, and the Open Access Scholarly Publishers Association. The company's offices are in Corte Madera (California, USA), and London (England, UK). Submitted research is judged solely on scientific and methodological soundness (as at '' PLoS ONE''), with a facility f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MRNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein. mRNA is created during the process of Transcription (biology), transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and the ribosome creates the protein utilizing amino acids carried by transfer RNA (tRNA). This process is known as Translation (biology), translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of geneti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Silencer
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include catalytic RNA molecules, also called ribozymes. They are sometimes described as a ''type'' of enzyme rather than being ''like'' an enzyme, but even in the decades s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zebrafish
The zebrafish (''Danio rerio'') is a species of freshwater ray-finned fish belonging to the family Danionidae of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a " tropical fish" although it is both tropical and subtropical). The zebrafish is an important and widely used vertebrate model organism in scientific research, particularly developmental biology, but also gene function, oncology, teratology, and drug development, in particular pre-clinical development. It is also notable for its regenerative abilities, and has been modified by researchers to produce many transgenic strains. Taxonomy The zebrafish is a derived member of the genus '' Brachydanio'', of the family Cyprinidae. It has a sister-group relationship with '' Danio aesculapii''. Zebrafish are also closely related to the genus '' Devario'', as demonstrated by a phylogenetic tree of close species. Distri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIV Virus
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, the average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. In most cases, HIV is a sexually transmitted infection and occurs by contact with or transfer of blood, pre-ejaculate, semen, and vaginal fluids. Non-sexual transmission can occur from an infected mother to her infant during pregnancy, during childbirth by exposure to her blood or vaginal fluid, and through breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. Research has shown (for both same-sex and opposite-sex couples) that HIV is not contagious duri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Micro-RNA
Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in messenger RNA (mRNA) molecules, then silence said mRNA molecules by one or more of the following processes: * Cleaving the mRNA strand into two pieces. * Destabilizing the mRNA by shortening its poly(A) tail. * Reducing translation of the mRNA into proteins. In cells of humans and other animals, miRNAs primarily act by destabilizing the mRNA. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short stem-loops (hairpins), whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Biology
Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and data science, the field also has foundations in applied mathematics, molecular biology, cell biology, chemistry, and genetics. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via Punched card, punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting relevant information. Per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
