Thomas Nettleton
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Thomas Nettleton
Thomas Nettleton (1683–1742) was an English physician who carried out some of the earliest systematic programmes of smallpox inoculation and who went on to statistical investigation of the outcomes. Little is known of Nettleton other than that he was a physician in Halifax Yorkshire. By 1722, Nettleton was aware of several early accounts of inoculation when a smallpox outbreak occurred in his area. He went on to inoculate at least sixty people and reported the results in 1724. However, it was only later that year that he considered the difference in mortality between those who had received the smallpox inoculation and those who had not. It was his letter to James Jurin James Jurin FRS FRCP (baptised 15 December 168429 March 1750) was an English scientist and physician, particularly remembered for his early work in capillary action and in the epidemiology of smallpox vaccination. He was a staunch proponent o ... that motivated Jurin himself to gather further data an ...
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England
England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe by the North Sea to the east and the English Channel to the south. The country covers five-eighths of the island of Great Britain, which lies in the North Atlantic, and includes over 100 smaller islands, such as the Isles of Scilly and the Isle of Wight. The area now called England was first inhabited by modern humans during the Upper Paleolithic period, but takes its name from the Angles, a Germanic tribe deriving its name from the Anglia peninsula, who settled during the 5th and 6th centuries. England became a unified state in the 10th century and has had a significant cultural and legal impact on the wider world since the Age of Discovery, which began during the 15th century. The English language, the Anglican Church, and Engli ...
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their ...
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Smallpox Vaccine
The smallpox vaccine is the first vaccine to be developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the 20th century. From 1958 to 1977, the World Health Organization (WHO) conducted a global vaccination campaign that eradicated smallpox, making it the only human disease to be eradicated. Although routine smallpox vaccination is no longer performed on the general public, the vaccine is still being produced to guard against bioterrorism, biological warfare, and monkeypox.Anderson MG, Frenkel LD, Homann S, and Guffey J. (2003), "A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values"; ''Pediatr Infect Dis J'';22(12): 1093–96; discussion 1096–98. The term ''vaccine'' derives from the Latin ...
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Statistics
Statistics (from German: '' Statistik'', "description of a state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of surveys and experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey samples. Representative sampling assures that inferences and conclusions can reasonably extend from the sample to the population as a whole. An ...
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Halifax, West Yorkshire
Halifax () is a minster and market town in the Metropolitan Borough of Calderdale in West Yorkshire, England. It is the commercial, cultural and administrative centre of the borough, and the headquarters of Calderdale Council. In the 15th century, the town became an economic hub of the old West Riding of Yorkshire, primarily in woollen manufacture. Halifax is the largest town in the wider Calderdale borough. Halifax was a thriving mill town during the industrial revolution. Toponymy The town's name was recorded in about 1091 as ''Halyfax'', from the Old English ''halh-gefeaxe'', meaning "area of coarse grass in the nook of land". This explanation is preferred to derivations from the Old English ''halig'' (holy), in ''hālig feax'' or "holy hair", proposed by 16th-century antiquarians. The incorrect interpretation gave rise to two legends. One concerned a maiden killed by a lustful priest whose advances she spurned. Another held that the head of John the Baptist was buried her ...
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Yorkshire
Yorkshire ( ; abbreviated Yorks), formally known as the County of York, is a historic county in northern England and by far the largest in the United Kingdom. Because of its large area in comparison with other English counties, functions have been undertaken over time by its subdivisions, which have also been subject to periodic reform. Throughout these changes, Yorkshire has continued to be recognised as a geographic territory and cultural region. The name is familiar and well understood across the United Kingdom and is in common use in the media and the military, and also features in the titles of current areas of civil administration such as North Yorkshire, South Yorkshire, West Yorkshire and the East Riding of Yorkshire. Within the borders of the historic county of Yorkshire are large stretches of countryside, including the Yorkshire Dales, North York Moors and Peak District national parks. Yorkshire has been nicknamed "God's Own Country" or "God's Own County" by its i ...
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Royal College Of Surgeons Of Edinburgh
The Royal College of Surgeons of Edinburgh (RCSEd) is a professional organisation of surgeons. The College has seven active faculties, covering a broad spectrum of surgical, dental, and other medical practices. Its main campus is located on Nicolson Street, Edinburgh, within the Surgeons' Hall, designed by William Henry Playfair, and adjoining buildings. The main campus includes a skills laboratory, the Surgeons' Hall Museums, a medical and surgical library, and a hotel. A second office was opened in Birmingham (UK) in 2014 and an international office opened in Kuala Lumpur, Malaysia, in 2018. It is one of the oldest surgical corporations in the world and traces its origins to 1505, when the Barber Surgeons of Edinburgh were formally incorporated as a craft of Edinburgh. The Barber-Surgeons of Dublin was the first medical corporation in Ireland or Britain, having been incorporated in 1446 (by Royal Decree of Henry VI). RCSEd represents members and fellows across the UK ...
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Mortality Rate
Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time. Mortality rate is typically expressed in units of deaths per 1,000 individuals per year; thus, a mortality rate of 9.5 (out of 1,000) in a population of 1,000 would mean 9.5 deaths per year in that entire population, or 0.95% out of the total. It is distinct from " morbidity", which is either the prevalence or incidence of a disease, and also from the incidence rate (the number of newly appearing cases of the disease per unit of time). An important specific mortality rate measure is the crude death rate, which looks at mortality from all causes in a given time interval for a given population. , for instance, the CIA estimates that the crude death rate globally will be 7.7 deaths per 1,000 people in a population per year. In a generic form, mortality rates can be seen as calculated using ...
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James Jurin
James Jurin FRS FRCP (baptised 15 December 168429 March 1750) was an English scientist and physician, particularly remembered for his early work in capillary action and in the epidemiology of smallpox vaccination. He was a staunch proponent of the work of Sir Isaac Newton and often used his gift for satire in Newton's defence. Early life Jurin's father was John Jurin, a London dyer. His mother was John's wife Dorcas Cotesworth. He was educated at Christ's Hospital where he won a scholarship to Trinity College, Cambridge, graduating BA in 1705, and being elected fellow the following year. Becoming the ''protégé'' of the master of Trinity, Richard Bentley, Jurin became tutor to Mordecai Cary, travelling with him internationally. Jurin achieved his MA in 1709 and became headteacher of the Royal Grammar School, Newcastle. Jurin became a frequent public speaker on mathematics and the work of Sir Isaac Newton. Jurin returned to Cambridge in 1715 to study medicine, becoming MD ...
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1683 Births
Events January–March * January 5 – The Brandenburger—African Company, of the German state of Brandenburg, signs a treaty with representatives of the Ahanta tribe (in what is now Ghana), to establish the fort and settlement of Groß Friedrichsburg, in honor of Frederick William, Elector of Brandenburg. The location is later renamed Princes Town, also called Pokesu. * January 6 – The tragic opera '' Phaëton'', written by Jean-Baptiste Lully and Philippe Quinault, is premiered at the Palace of Versailles. * January 27 – Gove's Rebellion breaks out in the Province of New Hampshire in North America as a revolt against the Royal Governor, Edward Cranfield. Most of the participants, and their leader Edward Gove, are arrested. Gowe is convicted of treason but pardoned three years later. * February 7 – The opera '' Giustino'' by Giovanni Legrenzi and about the life of the Byzantine Emperor Justin, premieres in Venice. * March 14 – Agen ...
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1742 Deaths
Year 174 ( CLXXIV) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Gallus and Flaccus (or, less frequently, year 927 ''Ab urbe condita''). The denomination 174 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Empress Faustina the Younger accompanies her husband, Marcus Aurelius, on various military campaigns and enjoys the love of the Roman soldiers. Aurelius gives her the title of ''Mater Castrorum'' ("Mother of the Camp"). * Marcus Aurelius officially confers the title ''Fulminata'' ("Thundering") to the Legio XII Fulminata. Asia * Reign in India of Yajnashri Satakarni, Satavahana king of the Andhra. He extends his empire from the center to the north of India. By topic Art and Science * ''Meditations'' by Marcus Aurelius is ...
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