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Takaki Kanehiro
Baron was a Japanese naval physician. Early life Born in Hyūga Province (present-day Miyazaki Prefecture) as the son of a '' samurai'' retainer to the Satsuma domain, Takaki studied Chinese medicine as a youth and served as a medic in the Boshin War. He later studied western medical science under British doctor William Willis (in Japan 1861–1881). Takaki entered the Imperial Japanese Navy as a medical officer in 1872. He was sent to Great Britain for medical studies in 1875, and interned at St Thomas's Hospital Medical School now part of King's College London in London. He returned to Japan in 1880. Work on beriberi At the time, beriberi (considered endemic to Japan) was a serious problem on warships and was affecting naval efficiency. Takaki knew that beriberi was not common among Western navies. He also noticed that Japanese naval officers, whose diet consisted of various types of vegetables and meat, rarely suffered from beriberi. On the other hand, the disease ...
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Hyūga Province
was an old province of Japan on the east coast of Kyūshū, corresponding to the modern Miyazaki Prefecture. Nussbaum, Louis-Frédéric. (2005). "''Hyūga''" in . It was sometimes called or . Hyūga bordered on Bungo, Higo, Ōsumi, and Satsuma Province. The ancient capital was near Saito. History In the ''Kojiki'' and the '' Nihon Shoki'', Hyūga is called of Tsukushi-no-shima (Kyushu), along the provinces of Tsukushi, Toyo and Hi. In the 3rd month of the 6th year of the '' Wadō'' era (713), the land of Hyūga was administratively separated from Ōsumi Province (大隅国). In that same year, Empress Genmei's ''Daijō-kan'' continued to organize other cadastral changes in the provincial map of the Nara period. Titsingh, Isaac. (1834). During the Sengoku period, the area was often divided into a northern fief around Agata castle (near modern Nobeoka), and a southern fief around Obi castle, near modern Nichinan. The southern fief was held by the Shimazu clan ...
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Beriberi
Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, resulting in a fast heart rate, shortness of breath, and leg swelling. Dry beriberi affects the nervous system, resulting in numbness of the hands and feet, confusion, trouble moving the legs, and pain. A form with loss of appetite and constipation may also occur. Another type, acute beriberi, found mostly in babies, presents with loss of appetite, vomiting, lactic acidosis, changes in heart rate, and enlargement of the heart. Risk factors include a diet of mostly white rice, alcoholism, dialysis, chronic diarrhea, and taking high doses of diuretics. In rare cases, it may be due to a genetic condition that results in difficulties absorbing thiamine found in food. Wernicke encephalopathy and Korsakoff syndrome are forms of dry beri ...
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Russo-Japanese War
The Russo-Japanese War ( ja, 日露戦争, Nichiro sensō, Japanese-Russian War; russian: Ру́сско-япóнская войнá, Rússko-yapónskaya voyná) was fought between the Empire of Japan and the Russian Empire during 1904 and 1905 over rival imperialism, imperial ambitions in Manchuria and the Korean Empire. The major theatres of military operations were located in Liaodong Peninsula and Shenyang, Mukden in Southern Manchuria, and the Yellow Sea and the Sea of Japan. Russia sought a Port#Warm-water port, warm-water port on the Pacific Ocean both for its navy and for maritime trade. Vladivostok remained ice-free and operational only during the summer; Lüshunkou, Port Arthur, a naval base in Liaodong Province leased to Russia by the Qing dynasty of China from 1897, was operational year round. Russia had pursued an expansionist policy east of the Urals, in Siberia and the Russian Far East, Far East, since the reign of Ivan the Terrible in the 16th century. Since th ...
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Tokyo Imperial University
, abbreviated as or UTokyo, is a public research university located in Bunkyō, Tokyo, Japan. Established in 1877, the university was the first Imperial University and is currently a Top Type university of the Top Global University Project by the Japanese government. UTokyo has 10 faculties, 15 graduate schools and enrolls about 30,000 students, about 4,200 of whom are international students. In particular, the number of privately funded international students, who account for more than 80%, has increased 1.75 times in the 10 years since 2010, and the university is focusing on supporting international students. Its five campuses are in Hongō, Komaba, Kashiwa, Shirokane and Nakano. It is considered to be the most selective and prestigious university in Japan. As of 2021, University of Tokyo's alumni, faculty members and researchers include seventeen prime ministers, 18 Nobel Prize laureates, four Pritzker Prize laureates, five astronauts, and a Fields Medalist. History ...
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Imperial Japanese Army
The was the official ground-based armed force of the Empire of Japan from 1868 to 1945. It was controlled by the Imperial Japanese Army General Staff Office and the Ministry of the Army, both of which were nominally subordinate to the Emperor of Japan as supreme commander of the army and the Imperial Japanese Navy. Later an Inspectorate General of Aviation became the third agency with oversight of the army. During wartime or national emergencies, the nominal command functions of the emperor would be centralized in an Imperial General Headquarters (IGHQ), an ad hoc body consisting of the chief and vice chief of the Army General Staff, the Minister of the Army, the chief and vice chief of the Naval General Staff, the Inspector General of Aviation, and the Inspector General of Military Training. History Origins (1868–1871) In the mid-19th century, Japan had no unified national army and the country was made up of feudal domains (''han'') with the Tokugawa shogunate (''b ...
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Infectious Disease
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. '' Mycobacterium tube ...
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Nutrition
Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient nutrients causes malnutrition. Nutritional science is the study of nutrition, though it typically emphasizes human nutrition. The type of organism determines what nutrients it needs and how it obtains them. Organisms obtain nutrients by consuming organic matter, consuming inorganic matter, absorbing light, or some combination of these. Some can produce nutrients internally by consuming basic elements, while some must consume other organisms to obtain preexisting nutrients. All forms of life require carbon, energy, and water as well as various other molecules. Animals require complex nutrients such as carbohydrates, lipids, and proteins, obtaining them by consuming other organisms. Humans have developed agriculture and cooking to repla ...
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidat ...
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Vitamin B1
Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient, that cannot be made in the body. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids. Food sources of thiamine include whole grains, legumes, and some meats and fish. Grain processing removes much of the vitamin content, so in many countries cereals and flours are enriched with thiamine. Supplements and medications are available to treat and prevent thiamine deficiency and disorders that result from it include beriberi and Wernicke encephalopathy. They are also used to treat maple syrup urine disease and Leigh syndrome. Supplements and medications are typically taken by mouth, but may also be given by intravenous or intramuscular injection. Thiamine supplements are generally well tolerated. Allergic reactions, including ...
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Nutritional Deficiency
Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is "a deficiency, excess, or imbalance of energy, protein and other nutrients" which adversely affects the body's tissues and form. Malnutrition is not receiving the correct amount of nutrition. Malnutrition is increasing in children under the age of five due to providers who cannot afford or do not have access to adequate nutrition. Malnutrition is a category of diseases that includes undernutrition and overnutrition. Undernutrition is a lack of nutrients, which can result in stunted growth, wasting, and underweight. A surplus of nutrients causes overnutrition, which can result in obesity. In some developing countries, overnutrition in the form of obesity is beginning to appear within the same communities as undernutrition. Most clinical studies use the term 'malnutrition' to refer to undernutrition. However, the use of 'malnutrition' instead of 'undern ...
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Jakarta
Jakarta (; , bew, Jakarte), officially the Special Capital Region of Jakarta ( id, Daerah Khusus Ibukota Jakarta) is the capital city, capital and list of Indonesian cities by population, largest city of Indonesia. Lying on the northwest coast of Java, the world's list of islands by population, most populous island, Jakarta is the list of cities in ASEAN by population, largest city in Southeast Asia and serves as the diplomatic capital of ASEAN. The city is the economic, cultural, and political centre of Indonesia. It possesses a province-level status and has a population of 10,609,681 as of mid 2021.Badan Pusat Statistik, Jakarta, 2022. Although Jakarta extends over only , and thus has the smallest area of any Provinces of Indonesia, Indonesian province, its Jakarta metropolitan area, metropolitan area covers , which includes the satellite cities Bogor, Depok, Tangerang, South Tangerang, and Bekasi, and has an estimated population of 35 million , making it the List of m ...
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Christiaan Eijkman
Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with Sir Frederick Hopkins, he received the Nobel Prize for Physiology or Medicine in 1929 for the discovery of vitamins. Biography Early life and education Christiaan Eijkman was born on 11 August 1858, at Nijkerk, Netherlands as the seventh child of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His elder brother Johann Frederik Eijkman (1851–1915) was also a chemist. A year later, in 1859, the Eijkman family moved to Zaandam, where his father was appointed head of a newly founded school for advanced elementary education. It was here that Christiaan and his brothers received their early education. In 1875, after taking his preliminary examinations, Eijkman became a student at the Military Medical School o ...
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