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Twist Bioscience
Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck. The company was represented by Leproust at a March 2021 tabletop exercise at the Munich Security Conference simulating an outbreak of weaponized monkeypox. In May 2021, Twist Bioscience and Genome Project-Write launched a new CAD platform for whole genome design. The CAD will automate workflows to enable collaborative efforts critical for scale-up from designing plasmids to megabases A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both DNA ... across entire genomes. References {{Reflist Companies based in South San Francisco, California Amer ...
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Public Company
A public company is a company whose ownership is organized via shares of share capital, stock which are intended to be freely traded on a stock exchange or in over-the-counter (finance), over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listing (finance), listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states and so have associations and formal designations, which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation, though a corporation need not be a public company. In the United Kin ...
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Russell 2000
The Russell 2000 Index is a small-cap U.S. stock market index that makes up the smallest 2,000 stocks in the Russell Index. It was started by the Frank Russell Company in 1984. The index is maintained by FTSE Russell, a subsidiary of the London Stock Exchange Group (LSEG). Overview The Russell 2000 is by far the most common benchmark for mutual funds that identify themselves as "small-cap", while the S&P 500 index is used primarily for large capitalization stocks. It is the most widely quoted measure of the overall performance of small-cap to mid-cap company shares. It is commonly considered an indicator of the U.S. economy due to its focus on small-cap companies in the U.S. market. The index represents approximately 7% of the total market capitalization of the Russell 3000 Index. , the weighted average market capitalization of a company in the index is approximately $3.65 billion and the median market capitalization is approximately $0.99 billion. The market cap ...
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South San Francisco, California
South San Francisco is a city in San Mateo County, California, United States, on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially termed "South City". The population was 66,105 at the 2020 United States census, 2020 census. History Prior to European exploration, the location was populated for more than 5,000 years. The northern San Francisco peninsula was inhabited by the Ramaytush, a linguistic sub-group of the Ohlone people. Their village of Ramaytush#Ramaytush tribes and villages, Urebure on San Bruno Creek was visited by the Gaspar de Portolà expedition in 1769; remains of long-term (5,000+ years) inhabitancy and seasonal encampments have been examined at the Ramaytush#Ramaytush tribes and villages, Siplichiquin and Buckeye shell-mounds on San Bruno Mountain. Charcoal-sampling indicates these ancient sites were actively occupied into the Spanish colonial period (late 1700s). The delta of Colma Creek was formerly an important habitat for t ...
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Biotechnology Companies
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create n ...
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South San Francisco
South San Francisco is a city in San Mateo County, California, United States, on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially termed "South City". The population was 66,105 at the 2020 census. History Prior to European exploration, the location was populated for more than 5,000 years. The northern San Francisco peninsula was inhabited by the Ramaytush, a linguistic sub-group of the Ohlone people. Their village of Urebure on San Bruno Creek was visited by the Gaspar de Portolà expedition in 1769; remains of long-term (5,000+ years) inhabitancy and seasonal encampments have been examined at the Siplichiquin and Buckeye shell-mounds on San Bruno Mountain. Charcoal-sampling indicates these ancient sites were actively occupied into the Spanish colonial period (late 1700s). The delta of Colma Creek was formerly an important habitat for the waterfowl known to be hunted by the Ramaytush in historic times, and archaeologic sites have been re ...
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Synthetic DNA
Synthetic genomics is a nascent field of synthetic biology that uses aspects of genetic modification on pre-existing life forms, or artificial gene synthesis to create new DNA or entire lifeforms. Overview Synthetic genomics is unlike genetic modification in the sense that it does not use naturally occurring genes in its life forms. It may make use of custom designed base pair series, though in a more expanded and presently unrealized sense synthetic genomics could utilize genetic codes that are not composed of the two base pairs of DNA that are currently used by life. The development of synthetic genomics is related to certain recent technical abilities and technologies in the field of genetics. The ability to construct long base pair chains cheaply and accurately on a large scale has allowed researchers to perform experiments on genomes that do not exist in nature. Coupled with the developments in protein folding models and decreasing computational costs the field of synthet ...
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Munich Security Conference
The Munich Security Conference (MSC), formerly Munich Conference on Security Policy, is an annual conference on international security policy that has been held in Munich, Germany, since 1963. Over the past four decades the Munich Security Conference has become the most important independent forum for the exchange of views by international security policy decision-makers. Each year it brings together about 350 senior figures from more than 70 countries around the world to engage in an intensive debate on current and future security challenges. The list of attendees includes Head of state, heads of states, governments and International organization, international organizations, Minister (government), ministers, Member of parliament, members of parliament, high-ranking representatives of Military, armed forces, Scientist, science, civil society, as well as business and Mass media, media. The conference is held annually in February. The venue is the Hotel Bayerischer Hof, Munich, ...
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Monkeypox
Mpox (, ; formerly known as monkeypox) is an infectious viral disease that can occur in humans and other animals. Symptoms include a rash that forms blisters and then crusts over, fever, and lymphadenopathy, swollen lymph nodes. The illness is usually mild, and most infected individuals recover within a few weeks without treatment. The time from incubation period, exposure to the onset of symptoms ranges from three to seventeen days, and symptoms typically last from two to four weeks. However, cases may be severe, especially in children, pregnant women, or people with Immunodeficiency, suppressed immune systems. The disease is caused by the monkeypox virus, a zoonotic virus in the genus ''Orthopoxvirus''. The variola virus, which causes smallpox, is also in this genus. Human-to-human transmission can occur through direct contact with infected skin or body fluids, including sexual contact. People remain infectious from the onset of symptoms until all the lesions have scabbed ...
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Nuclear Threat Initiative
The Nuclear Threat Initiative, generally referred to as NTI, is a non-profit organization located in Washington, D.C. NTI was founded in 2001 by former U.S. Senator Sam Nunn and philanthropist Ted Turner and describes itself as a "a nonprofit, nonpartisan global security organization focused on reducing nuclear, biological, and emerging technology threats imperiling humanity." NTI has four policy programs: the Global Nuclear Policy Program, Nuclear Materials Security, Emerging Tech, and Global Biological Policy and Programs (stylized as NTI , bio). Mission The Nuclear Threat Initiative is a nonprofit, nonpartisan global security organization focused on reducing nuclear, biological, and emerging technology threats imperiling humanity. History NTI was founded in 2001 by former U.S. Senator Sam Nunn and philanthropist Ted Turner. The launch event was held at the National Press Club on January 8, 2001. An event celebrating NTI's 20th anniversary was held on April 12, 2022, with ...
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Genome Project-Write
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondrial DNA, mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplast DNA, chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been Whole-genome sequencing, sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project ...
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Computer-aided Design
Computer-aided design (CAD) is the use of computers (or ) to aid in the creation, modification, analysis, or optimization of a design. This software is used to increase the productivity of the designer, improve the quality of design, improve communications through documentation, and to create a database for manufacturing. Designs made through CAD software help protect products and inventions when used in patent applications. CAD output is often in the form of electronic files for print, machining, or other manufacturing operations. The terms computer-aided drafting (CAD) and computer-aided design and drafting (CADD) are also used. Its use in designing electronic systems is known as ''electronic design automation'' (''EDA''). In mechanical design it is known as ''mechanical design automation'' (''MDA''), which includes the process of creating a technical drawing with the use of computer software. CAD software for mechanical design uses either vector-based graphics to depict t ...
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