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The Skin I Live In
''The Skin I Live In'' () is a 2011 Spanish psychological thriller film written and directed by Pedro Almodóvar, starring Antonio Banderas, Elena Anaya, Marisa Paredes, Jan Cornet and Roberto Álamo. It is based on Thierry Jonquet's 1984 novel ''Mygale'', first published in French and then in English under the title ''Tarantula''. Almodóvar has described the film as "a horror story without screams or frights". The film was the first collaboration in 21 years between Almodóvar and Banderas since '' Tie Me Up! Tie Me Down!'' (1990). It premiered in May 2011 in competition at the 64th Cannes Film Festival, and won Best Film Not in the English Language at the 65th BAFTA Awards. It was also nominated for the Golden Globe Award for Best Foreign Language Film and 16 Goya Awards. Plot Plastic surgeon Robert Ledgard is successful in cultivating an artificial skin resistant to burns and insect bites, which he calls "Gal", that he says he has been testing on athymic mice. Pre ...
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In My Skin (film)
''In My Skin'' (French language, French: ''Dans ma peau'') is a 2002 New French Extremity Horror film, horror film written by, directed by, and starring Marina de Van. It details the downward mental spiral of Esther, a woman (played by de Van) who engages in increasingly destructive acts of self-harm, self-mutilation following an accident that injures her leg at a party. Plot One night, whilst attending a house party with colleagues, Esther (Marina de Van), a marketing professional in Paris, hurts her leg in the backyard on some industrial supplies. Alone when it happens, she doesn't even realize she has been hurt until much later, briefly inspecting the injury in an upstairs bathroom. After the party, Esther visits a doctor (Adrian de Van) who patches her up and wonders why she didn't initially feel the injury. Esther wonders too, but seems unconcerned about any cosmetic damage. He asks her jokingly, "Are you sure it's your leg?" The next day, while taking a bath, Esther be ...
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2011 Cannes Film Festival
The 64th Cannes Film Festival took place from 11 to 22 May 2011. American actor Robert De Niro served as the president of the jury for the main competition. American filmmaker Terrence Malick won the Palme d'Or, the festival's top prize, for the drama film '' The Tree of Life''. The festival opened with '' Midnight in Paris'' by Woody Allen, and closed with '' Beloved'' by Christophe Honoré. Mélanie Laurent hosted the opening and closing ceremonies. Italian film director Bernardo Bertolucci was presented with the third Honorary Award at the opening ceremony of the festival. Jailed Iranian film directors Jafar Panahi and Mohammad Rasoulof were honoured at the festival. '' Goodbye'' by Rasoulof and Panahi's '' This Is Not a Film'' were screened at the festival. For the first time ever, four female directors were featured in the main competition: Australian filmmaker Julia Leigh, Japanese filmmaker Naomi Kawase, Scottish filmmaker Lynne Ramsay and French filmmaker M ...
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Posttraumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a mental disorder that develops from experiencing a Psychological trauma, traumatic event, such as sexual assault, domestic violence, child abuse, warfare and its associated traumas, natural disaster, traffic collision, or other threats on a person's life or well-being. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress (medicine), distress to Psychological trauma, trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event and can include triggers such as misophonia. Young children are less likely to show distress, but instead may express their memories through play (activity), play. Most people who experience traumatic events do not develop PTSD. People who experience interpersonal violence such as rape, other sexual ...
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Transgenesis
Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Gene delivery must reach the genome of the host cell to induce gene expression. Successful gene delivery requires the foreign gene delivery to remain stable within the host cell and can either integrate into the genome or replicate independently of it. This requires foreign DNA to be synthesized as part of a vector, which is designed to enter the desired host cell and deliver the transgene to that cell's genome. Vectors utilized as the method for gene delivery can be divided into two categories, recombinant viruses and synthetic vectors (viral and non-viral). In complex multicellular eukaryotes (more specifically Weissmanists), if the transgene is incorporated into the host's germline cells, the resulting host cell can pass the transgene to its progeny. If the transgene is incorporated into somatic cells, the transgene will stay with the somatic cell line, and thus its ...
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Athymic Mice
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response. These xenografts are commonly used in research to test new methods of imaging and treating tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. Nomenclature The nomenclature for the nude mouse has changed several times since their discovery. Originally they were described as ''nu'' and this was updated to ''Hfh11nu'' when the mutated gene was identified as a mutation in the HNF-3/forkhead homolog 11 gene. Then in 2000, the gene responsible for the mutation was identified as a member of t ...
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Artificial Skin
Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans. The term was used in the late 1970s and early 1980s to describe a new treatment for massive burns. It was later discovered that treatment of deep skin wounds in adult animals and humans with this scaffold induces regeneration of the dermis. It has been developed commercially under the name Integra and is used in massively burned patients, during plastic surgery of the skin, and in treatment of chronic skin wounds. Alternatively, the term "artificial skin" sometimes is used to refer to skin-like tissue grown in a laboratory, although this technology is still quite a way away from being viable for use in the medical field. 'Artificial skin' can also refer to flexible semiconductor materials that can sense touch for those with prosthetic limbs (also experimental). Background The skin is the largest organ in the human body. Skin is made up of three layers, the epidermis, dermis and t ...
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Goya Awards
The Goya Awards () are Spain's main national annual film awards. They are presented by the Academy of Cinematographic Arts and Sciences of Spain. The first ceremony was held in 1987, a year after the founding of the Academy of Cinematographic Arts and Sciences, at the Lope de Vega Theatre (Madrid), Teatro Lope de Vega in Madrid. They have since been also held in other Spanish cities (Barcelona, Seville, Málaga, Valencia, Valladolid, and Granada). History To reward the best Spanish films of each year, the Spanish Academy of Motion Pictures and Arts decided to create the Goya Awards. The Goya Awards are Spain's main national film awards, considered by many in Spain, and internationally, to be the Spanish equivalent of the American Academy Awards. The inaugural ceremony took place on March 17, 1987, at the Lope de Vega Theatre (Madrid), Lope de Vega theatre in Madrid. From the 2nd edition until 1995, the awards were held at the Palacio de Congresos (Madrid), Palacio de Congresos ...
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Golden Globe Award For Best Foreign Language Film
The Golden Globe Award for Best Foreign Language Film is a Golden Globe Award presented by Dick Clark Productions to reward theatrically-released feature film not in the English language. It was first introduced at the 7th Golden Globe Awards for the 1949 film year as Best Foreign-Language Foreign Film, and would return to be awarded yearly from the 1957 film year onwards; from 1948 to 1972, it existed alongside the Best English-Language Foreign Film category, which was intended for English-language films made outside the United States. The two categories were fused into Best Foreign Language Film in 1973, now rewarding any non-American films regardless of language; this was reversed in 1986 when it was renamed to Best Foreign Language Film, although this last change also made American films in non-English language eligible, such as winners '' Letters from Iwo Jima'' and '' Minari''. The award was originally an equivalent to the pre-existent Best English-Language Foreign Film ...
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65th British Academy Film Awards
The 65th British Academy Film Awards, more commonly known as the BAFTAs, were held on 12 February 2012 at the Royal Opera House in London, honouring the best national and foreign films of 2011 in film, 2011. Presented by the British Academy of Film and Television Arts, accolades are handed out for the best feature-length film and documentaries of any nationality that were screened at British cinemas in 2011. The nominations were announced on 17 January 2012 by actor Daniel Radcliffe and actress Holliday Grainger. ''The Artist (film), The Artist'' won seven awards out of its twelve nominations, including Best Film, Best Director for Michel Hazanavicius, and Best Actor for Jean Dujardin. Meryl Streep won Best Actress for ''The Iron Lady (film), The Iron Lady''. Christopher Plummer won Best Supporting Actor for ''Beginners'' and Octavia Spencer won Best Supporting Actress for ''The Help (film), The Help''. ''Tinker Tailor Soldier Spy (film), Tinker Tailor Soldier Spy'', directed by ...
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BAFTA Award For Best Film Not In The English Language
The BAFTA Award for Best Film Not in the English Language is a film award given annually by the British Academy of Film and Television Arts and presented at the British Academy Film Awards. The award was first given at the 36th British Academy Film Awards, recognising the films of 1982, and until 1990 was known as the Best Foreign Language Film. Prior to this, films recorded in a language other than English were often recognised in the category BAFTA Award for Best Film, known between 1949 and 1969 as Best Film from any Source, also, in the 1980s there were only European films that the language originally recorded spoken in the film is not English, except '' Ran'', between winners and nominees films in this category. In the following lists, the titles and names in bold with a gold background are the winners and recipients respectively; those not in bold are the nominees. The years given are those in which the films under consideration were released, not the year of the ceremony, ...
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New York (magazine)
''New York'' is an American biweekly magazine concerned with life, culture, politics, and style generally, with a particular emphasis on New York City. Founded by Clay Felker and Milton Glaser in 1968 as a competitor to ''The New Yorker'' and ''The New York Times Magazine'', it was brasher in voice and more connected to contemporary city life and commerce, and became a cradle of New Journalism. Over time, it became more national in scope, publishing many noteworthy articles about American culture by writers such as Tom Wolfe, Jimmy Breslin, Nora Ephron, Pete Hamill, Jacob Weisberg, Michael Wolff (journalist), Michael Wolff, John Heilemann, Frank Rich, and Rebecca Traister. It was among the first "lifestyle magazines" meant to appeal to both male and female audiences, and its format and style have been emulated by many American regional and city publications. ''New York'' in its earliest days focused almost entirely on coverage of its namesake city, but beginning in the 1970s, ...
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Tie Me Up! Tie Me Down!
''Tie Me Up! Tie Me Down!'' (, , "Tie Me!") is a 1989 Spanish black romantic comedy film co-written and directed by Pedro Almodóvar, starring Victoria Abril and Antonio Banderas alongside Loles León, Francisco Rabal, Julieta Serrano, María Barranco, and Rossy de Palma. The plot follows a recently released psychiatric patient who kidnaps an actress in order to make her fall in love with him. He believes his destiny is to marry her and father her children. The film was highly successful with both critics and audiences in Spain. Its United States release was entangled in controversy, instrumental in the implementation by the MPAA of a new rating category, NC-17, for films of an explicit nature that were previously categorized as pornographic due to the X rating. Plot Ricky, a 23-year-old psychiatric patient, has been deemed cured and is released from a psych hospital. Until then, he has been the lover of the hospital's female director. An orphan, free, and alone, his go ...
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