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TRF Component Layout
TRF may refer to: Medicine and Science * Terminal restriction fragments, used in measuring telomere length * Thyrotropin-releasing factor, a peptide hormone secreted by the hypothalamus * Time-restricted feeding, a type of intermittent fasting * Transfer RNA-derived fragment * TERF1, Telomeric repeat-binding factor 1 (also known as TRF1) Places * Sandefjord Airport, Torp, Norway, IATA code * Thief River Falls, Minnesota, USA Organisations * Tactical recognition flash, UK armed forces * Texas Renaissance Festival, USA * Thoroughbred Retirement Foundation, racehorse rescue organization * TRF (group), a J-pop group * Regional Federal Courts (Portuguese: '), Brazilian Federal appellate courts * The Resistance Front, a separatist group in Indian Kashmir Other * Tuned radio frequency receiver, a type of radio * Trinidadian Creole Trinidadian Creole is an creole language commonly spoken throughout the island of Trinidad in Trinidad and Tobago. It is distinct from Tobagoni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Telomere
A telomere (; ) is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes (see #Sequences, Sequences). Telomeres are a widespread genetic feature most commonly found in eukaryotes. In most, if not all species possessing them, they protect the terminal regions of DNA, chromosomal DNA from progressive degradation and ensure the integrity of linear chromosomes by preventing DNA repair systems from mistaking the very ends of the DNA strand for a double-strand break. Discovery The existence of a special structure at the ends of chromosomes was independently proposed in 1938 by Hermann Joseph Muller, studying the fruit fly ''Drosophila melanogaster'', and in 1939 by Barbara McClintock, working with maize. Muller observed that the ends of irradiated fruit fly chromosomes did not present alterations such as deletions or inversions. He hypothesized the presence of a protective cap, which he coined "telomeres", from the Greek ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thyrotropin-releasing Factor
Thyrotropin-releasing hormone (TRH) is a hypophysiotropic hormone produced by neurons in the hypothalamus that stimulates the release of thyroid-stimulating hormone (TSH) as well as prolactin from the anterior pituitary. TRH has been used clinically in diagnosis of hyperthyroidism, and for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans. Its pharmaceutical form is called protirelin (INN) (). Physiology Synthesis and release TRH is synthesized within parvocellular neurons of the paraventricular nucleus of the hypothalamus. It is translated as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Gln-His-Pro-Gly-, with both ends of the sequence flanked by Lys-Arg or Arg-Arg sequences. To produce the mature form, a series of enzymes are required. First, a protease cleaves to the C-terminal side of the flanking Lys-Arg or Arg-Arg. Second, a carboxypeptidase removes the Lys/Arg residues leaving Gly as the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time-restricted Feeding
Intermittent fasting is any of various meal timing schedules that cycle between voluntary fasting (or reduced calorie intake) and non-fasting over a given period. Methods of intermittent fasting include alternate-day fasting, periodic fasting, such as the 5:2 diet, and daily time-restricted eating. Intermittent fasting has been studied to find whether it can reduce the risk of diet-related diseases, such as metabolic syndrome. A 2019 review concluded that intermittent fasting may help with obesity, insulin resistance, dyslipidemia, hypertension, and inflammation. There is preliminary evidence that intermittent fasting is generally safe. Adverse effects of intermittent fasting have not been comprehensively studied, leading some academics to point out its risk as a dietary fad. The US National Institute on Aging states that there is insufficient evidence to recommend intermittent fasting, and encourages speaking to one's healthcare provider about the benefits and risks before ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfer RNA
Transfer ribonucleic acid (tRNA), formerly referred to as soluble ribonucleic acid (sRNA), is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes). In a cell, it provides the physical link between the genetic code in messenger RNA (mRNA) and the amino acid sequence of proteins, carrying the correct sequence of amino acids to be combined by the protein-synthesizing machinery, the ribosome. Each three-nucleotide codon in mRNA is complemented by a three-nucleotide anticodon in tRNA. As such, tRNAs are a necessary component of translation, the biological synthesis of new proteins in accordance with the genetic code. Overview The process of translation starts with the information stored in the nucleotide sequence of DNA. This is first transformed into mRNA, then tRNA specifies which three-nucleotide codon from the genetic code corresponds to which amino acid. Each mRNA codon is recognized by a particular type of tRNA, which docks to it along ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TERF1
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the ''TERF1'' gene. Gene The human TERF1 gene is located in the chromosome 8 at 73,921,097-73,960,357 bp. Two transcripts of this gene are alternatively spliced products. The TERF1 gene is also known as TRF, PIN2 (Proteinase Inhibitor 2), TRF1, t-TRF1 and h-TRF1-AS. Protein The protein structure contains a C-terminal Myb motif, a dimerization domain (TERF homology) near its N-terminus and an acidic N-terminus. Subcellular distribution The cellular distribution of this DNA binding protein features the nucleoplasm, chromosomes, a telomeric region, a nuclear telomere cap complex, the cytoplasm, the spindle, the nucleus and a nucleolus and a nuclear chromosome. Function TERF 1 gene encodes a telomere specific protein which is a component of the telomere's shelterin nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sandefjord Airport, Torp
Sandefjord Airport, Torp (; ) is a minor international airport located northeast of Sandefjord and south of Oslo in Norway. The airport features a runway aligned 18/36. Torp partially serves as a regional airport for Vestfold and in part as a low-cost airport for Eastern Norway and the capital, Oslo. Widerøe have a base at Torp, serving both domestic and shorter international flights. It also sees scheduled flights by airBaltic, Ryanair, Wizz Air, Scandinavian Airlines, and Norwegian Air Shuttle. As of 2021, it was the second-largest airport in eastern Norway in terms of flights after Rygge shut down in 2016. The airport was built largely with NATO funding as one of several bases to be used by the United States Air Force in case of war. Construction started in 1953 and the airport was opened on 2 July 1956. By then, the military interest in the airport had dwindled. Civilian flights commenced in 1958, and in 1960, a municipal airport company was established to run a civili ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thief River Falls, Minnesota
Thief River Falls, sometimes abbreviated as TRF, is a city and county seat of Pennington County in the northwest portion of the U.S. state of Minnesota. The population was 8,749 at the 2020 census. History Thief River Falls takes its name from a geographic feature, the falls of the Red Lake River at its confluence with the Thief River. The name of the river is a loose translation of the Ojibwe phrase ''Gimood-akiwi ziibi'', literally, the "Stolen-land river" or "Thieving-land river", which originated when a band of Dakota Indians occupied a secret encampment along the river, hence "stealing" the land, before being discovered and routed by the neighboring Ojibwe. In the Treaty of Old Crossing of 1863, the ''Moose Dung's Indian Reservation'' was established on the west bank of the Thief River, at its confluence with Red Lake River. This Indian Reservation was dissolved in 1904 and their population incorporated as part of the Red Lake Band of Chippewa. Thief River Falls marke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tactical Recognition Flash
Tactical recognition flash (TRF) is the British military term for a coloured patch worn on the right arm of combat clothing by members of the British Army, Royal Navy and Royal Air Force. A TRF serves to quickly Combat identification, identify the regiment or corps of the wearer, in the absence of a cap badge. It is similar to, but distinct from, the DZ Flashes worn by members of Airborne Forces. TRFs should not be confused with formation signs or insignia, which are used to denote the formation (usually Brigade Insignia of the British Army, brigade or Divisional Insignia of the British Army, division or a higher headquarters) and are worn in addition to TRFs by a member of any regiment or corps serving in that formation. Army Royal Armoured Corps Army Air Corps Infantry Adjutant General's Corps Overseas Forces Historic Royal Air Force Cadet Forces Tactical Recognition Flashes are not to be worn by Cadet Force Adult Volunteers (CFAVs) or cadets ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Texas Renaissance Festival
The Texas Renaissance Festival (dubbed the Ren Fest) is an annual Renaissance fair located in Todd Mission, Texas, Todd Mission, Texas, about 55 miles northwest of Houston. The Texas Renaissance Festival (TRF) started in 1974 on the location of an old strip mining site. The festival claims to be "the nation’s largest Renaissance theme park." As of 2017, the festival sits on 55 acres of land, and offers over 200 acres of camping facilities to patrons. The festival regularly draws over half a million guests annually, making it the largest Renaissance festival in the country by attendance. History The TRF was founded in 1974 by brothers, David and George Coulam, on an abandoned strip mining site in what is now Todd Mission, Texas. At the time, it spanned fifteen acres, with three stages featuring small improvisational, improv theatre groups, and merchants selling their goods on blankets. The opening year saw a turn-out of 33,000. The fair has since grown to an annual attendance ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
