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T-maze
In behavioral science, a T-maze (or the variant Y-maze) is a simple forked passage used in animal cognition experiments.Olton, D.S. (1979). Mazes, maps, and memory. ''American Psychologist'', 34, 583–596). It is shaped like the letter T (or Y), providing the subject, typically a rodent, with a straightforward choice. T-mazes are used to study how the rodents function with memory and spatial learning through applying various stimuli. Starting in the early 20th century, rodents were used in experiments such as the T-maze. These concepts of T-mazes are used to assess rodent behavior. The different tasks, such as left-right discrimination and forced alternation, are mainly used with rodents to test reference and working memory. Apparatus The T-maze is one of a group of various mazes of differing sizes and many shapes. It is one of the most simple, consisting of just two turns – right or left. The maze is only able to be altered by blocking one of the two paths. The basis b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morris Water Navigation Task
The Morris water navigation task, also known as the Morris water maze (not to be confused with '' water maze''), is a behavioral procedure mostly used with rodents. It is widely used in behavioral neuroscience to study spatial learning and memory. It enables learning, memory, and spatial working to be studied with great accuracy, and can also be used to assess damage to particular cortical regions of the brain. It is used by neuroscientists to measure the effect of neurocognitive disorders on spatial learning and possible neural treatments, to test the effect of lesions to the brain in areas concerned with memory, and to study how age influences cognitive function and spatial learning. The task is also used as a tool to study drug-abuse, neural systems, neurotransmitters, and brain development. Overview The basic procedure for the Morris water navigation task is that the rat is placed in a large circular pool and is required to find an invisible or visible platform that allo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elevated Plus Maze
The elevated plus maze (EPM) is a test measuring anxiety in laboratory animals that usually uses Animal testing on rodents, rodents as a Drug discovery#Screening and design, screening test for putative anxiolytic or anxiogenic compounds and as a general research tool in neurobiology, neurobiological anxiety research such as PTSD and Traumatic brain injury, TBI. The model is based on the test animal's aversion to open spaces and tendency to be thigmotaxis, thigmotaxic. In the EPM, this anxiety is expressed by the animal spending more time in the enclosed arms. The validity of the model has been criticized as non-classical clinical anxiolytics produce mixed results in the EPM test. Despite this, the model is still commonly used for screening putative anxiolytics and for general research into the brain mechanisms of anxiety. Method The test uses an elevated, plus-shaped (+) apparatus with two open and two enclosed arms. The behavioral model is based on the general aversion of roden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
202109 T Maze Test Mouse Placed In One Arm With Food
1 (one, unit, unity) is a number, numeral, and glyph. It is the first and smallest positive integer of the infinite sequence of natural numbers. This fundamental property has led to its unique uses in other fields, ranging from science to sports, where it commonly denotes the first, leading, or top thing in a group. 1 is the unit of counting or measurement, a determiner for singular nouns, and a gender-neutral pronoun. Historically, the representation of 1 evolved from ancient Sumerian and Babylonian symbols to the modern Arabic numeral. In mathematics, 1 is the multiplicative identity, meaning that any number multiplied by 1 equals the same number. 1 is by convention not considered a prime number. In digital technology, 1 represents the "on" state in binary code, the foundation of computing. Philosophically, 1 symbolizes the ultimate reality or source of existence in various traditions. In mathematics The number 1 is the first natural number after 0. Each natural number, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus
The hippocampus (: hippocampi; via Latin from Ancient Greek, Greek , 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system. The hippocampus plays important roles in the Memory consolidation, consolidation of information from short-term memory to long-term memory, and in spatial memory that enables Navigation#Navigation in spatial cognition, navigation. In humans, and other primates the hippocampus is located in the archicortex, one of the three regions of allocortex, in each cerebral hemisphere, hemisphere with direct neural projections to, and reciprocal indirect projections from the neocortex. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Behavioural Sciences
Behavioural science is the branch of science concerned with human behaviour.Hallsworth, M. (2023). A manifesto for applying behavioural science. ''Nature Human Behaviour'', ''7''(3), 310-322. While the term can technically be applied to the study of behaviour amongst all living organisms, it is nearly always used with reference to humans as the primary target of investigation (though animals may be studied in some instances, e.g. invasive techniques). The behavioural sciences sit in between the conventional natural sciences and social studies in terms of scientific rigor. It encompasses fields such as psychology, neuroscience, linguistics, and economics.Sanders, M., Snijders, V., & Hallsworth, M. (2018). Behavioural science and policy: where are we now and where are we going?. ''Behavioural Public Policy'', ''2''(2), 144-167. Scope The behavioural sciences encompass both natural and social scientific disciplines, including various branches of psychology, neuroscience and bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oasis Maze
{{Short description, Test used in spatial memory research The oasis maze is a spatial memory task used in psychology and neuroscience research and is the dry version of the Morris water navigation task. It is a land-based spatial memory task in which a thirsty rat uses distal spatial cues to search an open field for a specific location (Oasis) containing water. The maze consists of an enclosed space (usually the same shape and dimensions of the space used in the Morris water maze) in which a small amount of water is hidden. A thirsty rat is then placed in the maze and learns where the water is by trial and error Trial and error is a fundamental method of problem-solving characterized by repeated, varied attempts which are continued until success, or until the practicer stops trying. According to W.H. Thorpe, the term was devised by C. Lloyd Morgan ( .... The maze tests memory by allowing the researcher to record the rat's performance on this task after it is learned and vario ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barnes Maze
The Barnes maze is a tool used in psychological laboratory experiments to measure spatial learning and memory. The test was first developed by Carol A. Barnes, Dr. Carol Barnes in 1979. The test subjects are usually rodents such as lab mouse, mice or lab rats, which either serve as a Scientific control, control or may have some Genetics, genetic variable or deficiency present in them which will cause them to react to the maze differently. The basic function of Barnes maze is to measure the ability of a mouse to learn and remember the location of a target zone using a configuration of distal visual cues located around the testing area. This noninvasive task is useful for evaluating novel chemical entities for their effects on cognition as well as identifying cognitive deficits in transgenic strains of rodents that model for disease such as Alzheimer's disease. It is also used by neuroscientists to determine whether there is a causative effect after mild traumatic brain injury on learni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spatial Navigation
In computing, spatial navigation is the ability to navigate between focusable elements, such as hyperlinks and form controls, within a structured document or user interface according to the spatial location. This method is widely used in application software like computer games. In the past Web browsers have used tabbing navigation to change the focus within an interface, by pressing the tab key of a computer keyboard to focus on the next element (or to focus on the previous one). The order is based on that in the source document. For HTML without any style, this method usually works as the spatial location of the element is in the same order of the source document. However, with the introduction of style via presentational attributes or style sheets such as CSS, this type of navigation is being used less often. Spatial navigation uses the arrow keys (with one or more modifier key held) to navigate on the "2D plane" of the interface. For example, pressing the "up" arrow k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Temporal Lobe
The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's temples. Structure The temporal lobe consists of structures that are vital for declarative or long-term memory. Declarative (denotative) or explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). The medial temporal lobe structures are critical for long-term memory, and include the hippocampal formation, perirhinal cortex, parahippocampal, and entorhinal neocortical regions. The hippocampus is critical for memory formation, and the surrounding medial temporal cortex is currently theorized to be critical f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Short-term Memory
Short-term memory (or "primary" or "active memory") is the capacity for holding a small amount of information in an active, readily available state for a short interval. For example, short-term memory holds a phone number that has just been recited. The duration of short-term memory (absent rehearsal or active maintenance) is estimated to be on the order of seconds. The commonly cited capacity of 7 items, found in Miller's Law, has been superseded by 4±1 items. In contrast, long-term memory holds information indefinitely. Short-term memory is not the same as working memory, which refers to structures and processes used for temporarily storing and manipulating information. Stores The idea of separate memories for short-term and long-term storage originated in the 19th century. A model of memory developed in the 1960s assumed that all memories are formed in one store and transfer to other stores after a small period of time. This model is referred to as the "modal model", mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Behavioral Science
Behavioural science is the branch of science concerned with Human behavior, human behaviour.Hallsworth, M. (2023). A manifesto for applying behavioural science. ''Nature Human Behaviour'', ''7''(3), 310-322. While the term can technically be applied to the study of behaviour amongst all living organisms, it is nearly always used with reference to humans as the primary target of investigation (though animals may be studied in some instances, e.g. invasive techniques). The behavioural sciences sit in between the conventional Natural science, natural sciences and social studies in terms of scientific rigor. It encompasses fields such as psychology, Behavioral neuroscience, neuroscience, linguistics, and Behavioral economics, economics.Sanders, M., Snijders, V., & Hallsworth, M. (2018). Behavioural science and policy: where are we now and where are we going?. ''Behavioural Public Policy'', ''2''(2), 144-167. Scope The behavioural sciences encompass both natural and social scientif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radial Arm Maze
The radial arm maze was designed by Olton and Samuelson in 1976 to measure spatial learning and memory in rats. The original apparatus consists of eight equidistantly spaced arms, each about 4 feet long, and all radiating from a small circular central platform (later versions have used as few as three and as many as 48 arms). At the end of each arm there is a food site, the contents of which are not visible from the central platform. Two types of memory that are assessed during the performance in this task are reference memory and working memory. Reference memory is assessed when the rats only visit the arms of the maze which contains the reward. The failure to do so will result in reference memory error. Working memory is assessed when the rats enter each arm a single time. Re-entry into the arms would result in a working memory error. The design ensures that, after checking for food at the end of each arm, the rat is always forced to return to the central platform before making ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
