Streptomycetaceae
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Streptomycetaceae
The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the first antibiotic against tuberculosis. Genomics Sequence alignments of actinomycetotal genomes have led to the identification of three conserved signature indels which are unique to the order Streptomycetales. The enzyme PBGD contains a four-amino-acid insertion which is present in all ''Streptomyces'' species and ''Kitasatospora setae'', but not any other Actinomycetota. Similarly, a one- amino-acid insertion is present in a conserved region of adenylate kinase and is found in all ''Streptomyces'' species and '' K. setae'', but is not found in any other Actinomycetota. Five conserved signature proteins have also been identified which are present in various sequenced ''Streptomyces'' species, but not in ''K. setae''; however, as the comple ...
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Streptomyces
''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Streptomycetes are characterised by a complex secondary metabolism. They produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomycin, streptomycin, cypemycin, grisemycin, bottromycins and chloramphenicol). The antibiotic streptomycin takes its name directly from ''Streptomyces''. Streptomycetes are infrequent pathogens, though infections in humans, such as mycetoma, can be caused by '' S. somaliensis'' and '' S. sudanensis'', and in plants can be caused by ' ...
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Streptomycineae
The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the first antibiotic against tuberculosis. Genomics Sequence alignments of actinomycetotal genomes have led to the identification of three conserved signature indels which are unique to the order Streptomycetales. The enzyme PBGD contains a four-amino-acid insertion which is present in all ''Streptomyces'' species and ''Kitasatospora setae'', but not any other Actinomycetota. Similarly, a one- amino-acid insertion is present in a conserved region of adenylate kinase and is found in all ''Streptomyces'' species and '' K. setae'', but is not found in any other Actinomycetota. Five conserved signature proteins have also been identified which are present in various sequenced ''Streptomyces'' species, but not in ''K. setae''; however, as the complete ...
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Streptacidiphilus
''Streptacidiphilus'' is an Actinobacteria genus in the family Streptomycetaceae The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the firs .... References Streptomycineae Bacteria genera {{actinobacteria-stub ...
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Kitasatospora
''Kitasatospora'' is an Actinobacteria genus in the family Streptomycetaceae The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the firs .... The genus name comes from Shibasaburo Kitasato, a Japanese bacteriologist. Species ''Kitasatospora'' comprises the following genera: * '' K. aburaviensis'' (Nishimura et al. 1957) Labeda et al. 2017 * '' K. acidiphila'' Kim et al. 2020 * '' K. albolonga'' (Tsukiura et al. 1964) Labeda et al. 2017 * '' K. arboriphila'' Groth et al. 2004 * '' K. atroaurantiaca'' (Nakagaito et al. 1993) Li et al. 2009 * '' K. aureofaciens'' (Duggar 1948) Labeda et al. 2017 * '' K. azatica'' corrig. (Nakagaito et al. 1993) Zhang et al. 1997 * '' K. cheerisanensis'' Chung et al. 1999 * '' K. cineracea'' Tajima et al. 2001 * '' K. cinereorecta'' (Terekhova and Preobrazhens ...
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Yinghuangia
''Yinghuangia'' is an Actinobacteria genus in the family Streptomycetaceae The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the firs .... References Streptomycineae Bacteria genera {{actinobacteria-stub ...
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Streptomyces Thermoautotrophicus
''Streptomyces thermoautotrophicus'' is a thermophilic bacterium species from the genus of ''Streptomyces ''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, ...''. ''Streptomyces thermoautotrophicus'' was claimed to be diazotrophic and to produce a new kind of nitrogenase, but new evidence suggests that it can't fix N2 gas. See also * List of Streptomyces species References Further reading * * * External linksType strain of ''Streptomyces thermoautotrophicus'' at Bac''Dive'' - the Bacterial Diversity Metadatabase thermoautotrophicus Bacteria described in 1991 {{Streptomyces-stub ...
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Embleya
''Embleya'' is an genus of Actinomycetota in the family Streptomycetaceae The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the firs .... References Streptomycineae Bacteria genera {{actinobacteria-stub ...
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Porphobilinogen Deaminase
Porphobilinogen deaminase (hydroxymethylbilane synthase, or uroporphyrinogen I synthase) is an enzyme () that in humans is encoded by the HMBS gene. Porphobilinogen deaminase is involved in the third step of the heme biosynthetic pathway. It catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane while releasing four ammonia molecules: :4 porphobilinogen + H2O \rightleftharpoons hydroxymethylbilane + 4 NH3 Structure and function Functionally, porphobilinogen deaminase catalyzes the loss of ammonia from the porphobilinogen monomer (deamination) and its subsequent polymerization to a linear tetrapyrrole, which is released as hydroxymethylbilane: The structure of 40-42 kDa porphobilinogen deaminase, which is highly conserved amongst organisms, consists of three domains. Domains 1 and 2 are structurally very similar: each consisting of five beta-sheets and three alpha helices in humans. Domain 3 is positioned between the oth ...
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Catenulisporales
The ''Catenulisporales'' are an order of bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am .... References Actinomycetia Bacteria orders {{actinobacteria-stub ...
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Outgroup (cladistics)
In cladistics or phylogenetics, an outgroup is a more distantly related group of organisms that serves as a reference group when determining the evolutionary relationships of the ingroup, the set of organisms under study, and is distinct from sociological outgroups. The outgroup is used as a point of comparison for the ingroup and specifically allows for the phylogeny to be rooted. Because the polarity (direction) of character change can be determined only on a rooted phylogeny, the choice of outgroup is essential for understanding the evolution of traits along a phylogeny. History Although the concept of outgroups has been in use from the earliest days of cladistics, the term "outgroup" is thought to have been coined in the early 1970s at the American Museum of Natural History. Prior to the advent of the term, various other terms were used by evolutionary biologists, including "exgroup", "related group", and "outside groups". Choice of outgroup The chosen outgroup is hypothes ...
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Catenulisporineae
The ''Catenulisporales'' are an order of bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometr .... References Actinomycetia Bacteria orders {{actinobacteria-stub ...
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