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Steffen Mueller
Steffen Mueller is a virologist and was assistant professor at Stony Brook University in New York. Mueller received his Ph.D. in molecular microbiology from Stony Brook University in 2002 in the laboratory of Eckard Wimmer. Mueller is a co-developer of the platform technology dubbed ''SAVE'' (Synthetic Attenuated Virus Engineering), a method to produce weakened synthetic viruses that are permanently prevented from regaining virulence. The method may hold the key to a new class of antiviral, so-called live, or attenuated vaccine An attenuated vaccine (or a live attenuated vaccine, LAV) is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live"). Attenuation takes an infectious agent and alters it so that it becomes harmless or less ...s. Mueller is co-founder and Chief Scientific Officer oCodagenix Inc. a New York-based biotechnology company engaged in the development of vaccines. References {{DEFAULTSORT:Mueller, Steffen America ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virologist
Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the full structure of the tobacco mosaic virus in 1955. Virology began ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stony Brook University
Stony Brook University (SBU), officially the State University of New York at Stony Brook, is a public research university in Stony Brook, New York. Along with the University at Buffalo, it is one of the State University of New York system's two flagship institutions. Its campus consists of 213 buildings on over of land in Suffolk County and it is the largest public university (by area) in the state of New York. Opened in 1957 in Oyster Bay as the State University College on Long Island, the institution moved to Stony Brook in 1962. In 2001, Stony Brook was elected to the Association of American Universities, a selective group of major research universities in North America. It is also a member of the larger Universities Research Association. It is classified among "R1: Doctoral Universities – Very high research activity". Stony Brook University, in partnership with Battelle, manages Brookhaven National Laboratory, a national laboratory of the United States Depa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York (state)
New York, officially the State of New York, is a state in the Northeastern United States. It is often called New York State to distinguish it from its largest city, New York City. With a total area of , New York is the 27th-largest U.S. state by area. With 20.2 million people, it is the fourth-most-populous state in the United States as of 2021, with approximately 44% living in New York City, including 25% of the state's population within Brooklyn and Queens, and another 15% on the remainder of Long Island, the most populous island in the United States. The state is bordered by New Jersey and Pennsylvania to the south, and Connecticut, Massachusetts, and Vermont to the east; it has a maritime border with Rhode Island, east of Long Island, as well as an international border with the Canadian provinces of Quebec to the north and Ontario to the northwest. New York City (NYC) is the most populous city in the United States, and around two-thirds of the state's popul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eckard Wimmer
Eckard Wimmer (born 22 May 1936) is a German American virologist, organic chemist and distinguished professor of molecular genetics and microbiology at Stony Brook University. He is best known for his seminal work on the molecular biology of poliovirus and the first chemical synthesis of a viral genome capable of infection and subsequent production of live viruses. Life and career Eckard Albert Friedrich Wimmer was born on May 22, 1936, in Berlin, Germany. At the onset of World War II, Wimmer at age three lost his father; at age nine, his mother fled together with his two older brothers to Saxony, East Germany, where he finished elementary school and high school. He studied Chemistry at the University of Rostock from 1953 to 1956, and then fled to West Germany to continue his Chemistry studies at University of Göttingen. In 1962 he earned the degree of Doctor rerum naturalium (Dr. rer. nat.) in the Organic Chemistry of natural products under the guidance of Hans Brockmann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virulence
Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism—its ability to cause disease—is determined by its virulence factors. In the specific context of gene for gene systems, often in plants, virulence refers to a pathogen's ability to infect a resistant host. The noun ''virulence'' derives from the adjective ''virulent'', meaning disease severity. The word ''virulent'' derives from the Latin word ''virulentus'', meaning "a poisoned wound" or "full of poison." From an ecological standpoint, virulence is the loss of fitness induced by a parasite upon its host. Virulence can be understood in terms of proximate causes—those specific traits of the pathogen that help make the host ill—and ultimate causes—the evolutionary pressures that lead to virulent traits occurring in a pathogen strain. Virulen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Attenuated Vaccine
An attenuated vaccine (or a live attenuated vaccine, LAV) is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live"). Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent. These vaccines contrast to those produced by "killing" the virus (inactivated vaccine). Attenuated vaccines stimulate a strong and effective immune response that is long-lasting. In comparison to inactivated vaccines, attenuated vaccines produce a stronger and more durable immune response with a quick immunity onset. Attenuated vaccines function by encouraging the body to create antibodies and memory immune cells in response to the specific pathogen which the vaccine protects against. Common examples of live attenuated vaccines are measles, mumps, rubella, yellow fever, and some influenza vaccines. Development Attenuated viruses Viruses may be attenuated using the principles of evolution via serial passage of the virus thro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Virologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
