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Startle Response
In animals, including humans, the startle response is a largely unconscious defensive response to sudden or threatening stimuli, such as sudden noise or sharp movement, and is associated with negative affect.Rammirez-Moreno, David. "A computational model for the modulation of the prepulse inhibition of the acoustic startle reflex". ''Biological Cybernetics'', 2012, p. 169 Usually the onset of the startle response is a startle reflex reaction. The startle reflex is a brainstem reflectory reaction (reflex) that serves to protect vulnerable parts, such as the back of the neck (whole-body startle) and the eyes (eyeblink) and facilitates escape from sudden stimuli. It is found across many different species, throughout all stages of life. A variety of responses may occur depending on the affected individual's emotional state, body posture, preparation for execution of a motor task, or other activities. The startle response is implicated in the formation of specific phobias. Startl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Affect (psychology)
Affect, in psychology, refers to the underlying experience of feeling, emotion or mood. History The modern conception of affect developed in the 19th century with Wilhelm Wundt. The word comes from the German ''Gefühl'', meaning "feeling." A number of experiments have been conducted in the study of social and psychological affective preferences (i.e., what people like or dislike). Specific research has been done on preferences, attitudes, impression formation, and decision-making. This research contrasts findings with recognition memory (old-new judgments), allowing researchers to demonstrate reliable distinctions between the two. Affect-based judgments and cognitive processes have been examined with noted differences indicated, and some argue affect and cognition are under the control of separate and partially independent systems that can influence each other in a variety of ways ( Zajonc, 1980). Both affect and cognition may constitute independent sources of effects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moro Reflex
The Moro reflex is an infantile reflex that develops between 28 and 32 weeks of gestation and disappears at 3–6 months of age. It is a response to a sudden loss of support and involves three distinct components: # spreading out the arms ( abduction) # pulling the arms in (adduction) # crying (usually) It is distinct from the startle reflex. Unlike the startle reflex, the Moro reflex does not decrease with repeated stimulation. The primary significance of the Moro reflex is in evaluating integration of the central nervous system. Eliciting the Moro reflex Ernst Moro elicited the Moro reflex by slapping the pillow on both sides of the infant's head. Other methods have been used since then, including rapidly lowering the infant (while supported) to a sudden stop and pinching the skin of the abdomen. Today, the most common method is the head drop, where the infant is supported in both hands and tilted suddenly so the head is a few centimeters lower than the level of the body. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of The American Academy Of Child & Adolescent Psychiatry
The ''Journal of the American Academy of Child and Adolescent Psychiatry'' is a peer-reviewed medical journal covering pediatric psychiatry. It is published by Elsevier and is the official journal of the American Academy of Child and Adolescent Psychiatry. The editor-in-chief is Douglas Novins. According to the ''Journal Citation Reports'', its 2014 impact factor is 7.26, ranking it first among 119 journals in the category "Pediatrics". It is abstracted and indexed in MEDLINE/PubMed, and Science Citation Index. Call for retraction The group Healthy Skepticism has accused the journal of having published an article, in 2001, that misrepresented the results of an industry-sponsored clinical trial, study 329. The study examined the use of paroxetine Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fight-or-flight Response
The fight-or-flight or the fight-flight-or-freeze response (also called hyperarousal or the acute stress response) is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival. It was first described by Walter Bradford Cannon. His theory states that animals react to threats with a general discharge of the sympathetic nervous system, preparing the animal for fighting or fleeing. More specifically, the adrenal medulla produces a hormonal cascade that results in the secretion of catecholamines, especially norepinephrine and epinephrine. The hormones estrogen, testosterone, and cortisol, as well as the neurotransmitters dopamine and serotonin, also affect how organisms react to stress. The hormone osteocalcin might also play a part. This response is recognised as the first stage of the general adaptation syndrome that regulates stress responses among vertebrates and other organisms. Name Originally understood as the fight-o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Journal Of Neuroscience
''The Journal of Neuroscience'' is a weekly peer-reviewed scientific journal published by the Society for Neuroscience. It covers empirical research on all aspects of neuroscience. Its editor-in-chief is Marina Picciotto (Yale University). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 6.167. History The journal was established in 1981 and issues appeared monthly; as its popularity grew it switched to a biweekly schedule in 1996 and then to a weekly in July 2003. Themes Main themes Articles appear within one of the following five sections of the journal: * Cellular/Molecular * Development/Plasticity/Repair * Systems/Circuits * Behavioral/Cognitive * Neurobiology of Disease The journal has revised its sections over the years. In 2004, it added the Neurobiology of Disease section due to the growing number of papers on this subject. In January 2013, the journal split the section Behavioral/Systems/Cognitive into two sections, Systems/Circu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anterior Cingulate Cortex
In the human brain The human brain is the central organ (anatomy), organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the act ..., the anterior cingulate cortex (ACC) is the frontal part of the cingulate cortex that resembles a "collar" surrounding the frontal part of the corpus callosum. It consists of Brodmann areas Brodmann area 24, 24, Brodmann area 32, 32, and Brodmann area 33, 33. It is involved in certain higher-level functions, such as attention allocation, pavlovian conditioning, reward anticipation, decision-making, ethics and morality, impulse control (e.g. performance monitoring and error detection), and emotion. Anatomy The anterior cingulate cortex can be divided anatomically based on cognitive (Dorsum (biology), dorsal), and emotional (ventral) components. The dorsal part of the ACC is connected with the prefrontal corte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stria Terminalis
The stria terminalis (or terminal stria) is a structure in the brain consisting of a band of fibers running along the lateral margin of the ventricular surface of the thalamus. Serving as a major output pathway of the amygdala, the stria terminalis runs from its centromedial division to the ventromedial nucleus of the hypothalamus. Anatomy The stria terminalis covers the superior thalamostriate vein, marking a line of separation between the thalamus and the caudate nucleus as seen upon gross dissection of the ventricles of the brain, viewed from the superior aspect. The stria terminalis extends from the region of the interventricular foramina to the temporal horn of the lateral ventricle, carrying fibers from the amygdala to the septal nuclei, hypothalamic, and thalamic areas of the brain. It also carries fibers projecting from these areas back to the amygdala. Bed nucleus of the stria terminalis (BNST) The activity of the bed nucleus of the stria terminalis correlate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus
The hippocampus (via Latin from Greek , ' seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located in the allocortex, with neural projections into the neocortex in humans, as well as primates. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In humans, it contains two main interlocking parts: the hippocampus proper (also called ''Ammon's horn''), and the dentate gyrus. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; short-term memory loss and disorientation are included among the early symptoms. Damage to the hippocampus can also result f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amygdala
The amygdala (; plural: amygdalae or amygdalas; also '; Latin from Greek, , ', 'almond', 'tonsil') is one of two almond-shaped clusters of nuclei located deep and medially within the temporal lobes of the brain's cerebrum in complex vertebrates, including humans. Shown to perform a primary role in the processing of memory, decision making, and emotional responses (including fear, anxiety, and aggression), the amygdalae are considered part of the limbic system. The term "amygdala" was first introduced by Karl Friedrich Burdach in 1822. Structure The regions described as amygdala nuclei encompass several structures of the cerebrum with distinct connectional and functional characteristics in humans and other animals. Among these nuclei are the basolateral complex, the cortical nucleus, the medial nucleus, the central nucleus, and the intercalated cell clusters. The basolateral complex can be further subdivided into the lateral, the basal, and the accessory basal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The European Journal Of Neuroscience
The ''European Journal of Neuroscience'' is a biweekly peer-reviewed scientific journal covering all aspects of neuroscience. It was established in 1989 with Ray Guillery (then at the University of Oxford) as the founding editor-in-chief. The editor-in-chief is John J. Foxe (University of Rochester) The journal is published by Wiley-Blackwell on behalf of the Federation of European Neuroscience Societies. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 3.386. Authors can elect to have accepted articles published as open access. EJN adopted transparent peer-review in January 2017. Sections Articles will appear within one of the five sections of the journal: * Molecular and Synaptic Mechanisms * Systems Neuroscience * Behavioural Neuroscience * Cognitive Neuroscience * Clinical and Translational Neuroscience Features EJN also publishespecialanissues related to topical issue in neuroscience. Editors-in-chief The following persons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PET Scan
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. For example, -FDG is commonly used to detect cancer, NaF is widely used for detecting bone formation, and oxygen-15 is sometimes used to measure blood flow. PET is a common imaging technique, a medical scintillography technique used in nuclear medicine. A radiopharmaceutical — a radioisotope attached to a drug — is injected into the body as a tracer. When the radiopharmaceutical undergoes beta plus decay, a positron is emitted, and when the positron collides with an ordinary electron, the two particles annihilate and gamma rays are emitted. These gamma rays are detec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
