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Smaug (protein)
Smaug is a RNA-binding protein in ''Drosophila'' that helps in maternal to zygotic transition (MZT). The protein is named after the fictional character Smaug, the dragon in J.R.R. Tolkien's 1937 novel ''The Hobbit''. The MZT ends with the midblastula transition (MBT), which is defined as the first developmental event in ''Drosophila'' that depends on zygotic mRNA. In ''Drosophila'', the initial developmental events are controlled by maternal mRNAs like ''Hsp83'', '' nanos'', ''string'', ''Pgc'', and ''cyclin B'' mRNA. Degradation of these mRNAs, which is expected to terminate maternal control and enable zygotic control of embryogenesis, happens at interphase of nuclear division cycle 14. During this transition smaug protein targets the maternal mRNA for destruction using miRs. Thus activating the zygotic genes. Smaug is expected to play a role in expression of three miRNAs – ''miR-3, miR-6, miR-309'' and ''miR-286'' during MZT in ''Drosophila''. Among them smaug dependent exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Translation Control Of Nanos MRNA By Smaug Protein
Translation is the communication of the Meaning (linguistic), meaning of a #Source and target languages, source-language text by means of an Dynamic and formal equivalence, equivalent #Source and target languages, target-language text. The English language draws a terminology, terminological distinction (which does not exist in every language) between ''translating'' (a written text) and ''Language interpretation, interpreting'' (oral or Sign language, signed communication between users of different languages); under this distinction, translation can begin only after the appearance of writing within a language community. A translator always risks inadvertently introducing source-language words, grammar, or syntax into the target-language rendering. On the other hand, such "spill-overs" have sometimes imported useful source-language calques and loanwords that have enriched target languages. Translators, including early translators of sacred texts, have helped shape the very l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
