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Saglin
Saglin is a protein produced by the salivary glands of mosquitoes. It is thought that this protein allows the malarial sporozoite to bind to the salivary glands, allowing invasion.Okulate ''et al.'' 2007 ''Identification and molecular characterization of a novel protein Saglin as a target of monoclonal antibodies affecting salivary gland infectivity of Plasmodium sporozoites'' It is currently under investigation as a potential drug target to help control transmission of the disease by controlling transmission in the vector Vector most often refers to: *Euclidean vector, a quantity with a magnitude and a direction *Vector (epidemiology), an agent that carries and transmits an infectious pathogen into another living organism Vector may also refer to: Mathematic ....The Saglin Project http://bioquest.org/oakwood2008/2008/08/this-is-the-saglin-project/ References {{reflist Proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mosquitoes
Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small Diptera, flies within the family Culicidae (from the Latin ''culex'' meaning "gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "little fly". Mosquitoes have a slender segmented body, one pair of wings, one pair of halteres, three pairs of long hair-like legs, and elongated mouthparts. The mosquito life cycle consists of egg, larva, pupa, and adult stages. Eggs are laid on the water surface; they hatch into Motility, motile larvae that feed on aquatic algae and organic material. These larvae are important food sources for many freshwater animals, such as Dragonfly, dragonfly nymphs, many fish, and some birds such as ducks. The adult females of most species have tube-like mouthparts (called a proboscis) that can pierce the skin of a Host (biology), host and Hematophagy, feed on blood, which contains protein and iron needed to produce eggs. Thousands of mosquito ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malarial
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be sprea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vector (epidemiology)
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen to another living organism; agents regarded as vectors are organisms, such as parasites or microbes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected a mosquito. Arthropods Arthropods form a major group of pathogen vectors with mosquitoes, flies, sand flies, lice, fleas, ticks, and mites transmitting a huge number of pathogens. Many such vectors are haematophagous, which feed on blood at some or all stages of their lives. When the insects feed on blood, the pathogen enters the blood stream of the host. This can happen in different ways. The '' Anopheles'' mosquito, a vector for malaria, filariasis, and various arthropod-borne-viruses ( arboviruses), inserts its delicate mouthpart under the skin and feeds on its host's blood. The parasites the mosquito carries are usually located in its sal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
