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SARS-CoV-2 Delta Variant
The Delta variant (B.1.617.2) was a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India in late 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021. The World Health Organization (WHO) indicated in June 2021 that the Delta variant was becoming the dominant strain globally. It has mutations in the gene encoding the SARS-CoV-2 spike protein causing the substitutions T478K, P681R and L452R, which are known to affect transmissibility of the virus as well as whether it can be neutralised by antibodies for previously circulating variants of the COVID-19 virus. In August 2021, Public Health England (PHE) reported secondary attack rate in household contacts of non-travel or unknown cases for Delta to be 10.8% ''vis-à-vis'' 10.2% for the Alpha variant; the case fatality rate for those 386,835 people with Delta is 0.3%, where 46% of the cases and 6% of the deaths are unvaccinated and below 50 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deltacoronavirus
''Deltacoronavirus'' (Delta-CoV) is one of the four genera ('' Alpha-'', '' Beta-'', '' Gamma-'', and ''Delta-'') of coronaviruses. It is in the subfamily ''Orthocoronavirinae'' of the family ''Coronaviridae''. They are enveloped, positive-sense, single-stranded RNA viruses. Deltacoronaviruses infect mostly birds and some mammals. While the alpha and beta genera are derived from the bat viral gene pool, the gamma and delta genera are derived from the avian and pig viral gene pools. Recombination appears to be common among deltacoronaviruses.Lau SKP, Wong EYM, Tsang CC, Ahmed SS, Au-Yeung RKH, Yuen KY, Wernery U, Woo PCY. Discovery and Sequence Analysis of Four Deltacoronaviruses from Birds in the Middle East Reveal Interspecies Jumping with Recombination as a Potential Mechanism for Avian-to-Avian and Avian-to-Mammalian Transmission. J Virol. 2018 Jul 17;92(15):e00265-18. doi: 10.1128/JVI.00265-18. Print 2018 Aug 1. PMID 29769348 Recombination occurs frequently in the v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Variant Of Concern
The term variant of concern (VOC) for SARS-CoV-2, which causes COVID-19, is a category used for variants of the virus where mutations in their spike protein receptor binding domain (RBD) substantially increase binding affinity (e.g., N501Y) in RBD-hACE2 complex (genetic data), while also being linked to rapid spread in human populations (epidemiological data). Before this, an emerging variant may have been labeled a variant of interest, or in some countries a variant under investigation. During or after fuller assessment as a variant of concern the variant is typically assigned to a lineage in the PANGOLIN nomenclature system and to clades in the Nextstrain and GISAID systems. During the COVID-19 pandemic, the SARS-CoV-2 virus has been observed to mutate, with certain combinations of specific point mutations proving to be more concerning than others. This was principally for reasons of transmissibility and virulence, and also with regard to the possible emergence of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clade
A clade (), also known as a monophyletic group or natural group, is a group of organisms that are monophyletic – that is, composed of a common ancestor and all its lineal descendants – on a phylogenetic tree. Rather than the English term, the equivalent Latin term ''cladus'' (plural ''cladi'') is often used in taxonomical literature. The common ancestor may be an individual, a population, or a species (extinct or extant). Clades are nested, one in another, as each branch in turn splits into smaller branches. These splits reflect evolutionary history as populations diverged and evolved independently. Clades are termed monophyletic (Greek: "one clan") groups. Over the last few decades, the cladistic approach has revolutionized biological classification and revealed surprising evolutionary relationships among organisms. Increasingly, taxonomists try to avoid naming taxa that are not clades; that is, taxa that are not monophyletic. Some of the relationships between org ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In New Zealand
The COVID-19 pandemic in New Zealand is part of COVID-19 pandemic, the ongoing pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The first case of the disease in New Zealand was reported on 28 February 2020. , the country has had a total of 2,062,384 cases (2,027,981 confirmed and 34,403 probable). 2,288 people have died as a result of the virus, with cases recorded in all twenty district health board (DHB) areas. The pandemic first peaked in early April 2020, with 89 new cases recorded per day and 929 active cases. Cases peaked again in October 2021 with 134 new cases reported on 22 October. A total of 7,274,347 COVID tests have been carried out . In response to the first outbreak in late February 2020, the New Zealand Government closed the country's borders and imposed lockdown restrictions. A four-tier #Alert level system, alert level system was introduced on 21 March 2020 to manage the outbreak within New Zealand. Sin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Australia
The COVID-19 pandemic in Australia is part of the ongoing worldwide pandemic of the coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The first confirmed case in Australia was identified on 25 January 2020, in Victoria, when a man who had returned from Wuhan, Hubei Province, China, tested positive for the virus. , Australia has reported over 9,588,977 cases, over 9,224,255 recoveries, and 12,200 deaths. Victoria's second wave having the highest fatality rate per case. In March 2020, the Australian government established the intergovernmental National Cabinet and declared a human biosecurity emergency in response to the outbreak. Australian borders were closed to all non-residents on 20 March, and returning residents were required to spend two weeks in supervised quarantine hotels from 27 March. Many individual states and territories also closed their borders to varying degrees, with some remaining closed until late 2020, and contin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In The United States
The COVID-19 pandemic in the United States is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United States, it has resulted in confirmed cases with all-time deaths, the most of any country, and the twentieth-highest per capita worldwide. The COVID-19 pandemic ranks first on the list of disasters in the United States by death toll; it was the third-leading cause of death in the U.S. in 2020, behind heart disease and cancer. From 2019 to 2020, U.S. life expectancy dropped by 3years for Hispanic and Latino Americans, 2.9years for African Americans, and 1.2years for white Americans. These effects persisted as U.S. deaths due to COVID-19 in 2021 exceeded those in 2020, and life expectancy continued to fall from 2020 to 2021. On December 31, 2019, China announced the discovery of a cluster of pneumonia cases in Wuhan. The first American case was reported on January 20, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Asia
The COVID-19 pandemic began in Asia in Wuhan, Hubei, China, and has spread widely through the continent. As of , at least one case of COVID-19 had been reported in every country in Asia except Turkmenistan. The Asian countries with the highest numbers of confirmed coronavirus cases are India, South Korea, Turkey, Vietnam, and Iran. Despite being the first area of the world hit by the outbreak, the early wide-scale response of some Asian states, particularly Bhutan, Singapore, Taiwan, and Vietnam has allowed them to fare comparatively well. China was criticised for initially minimising the severity of the outbreak, but its wide-scale response has largely contained the disease since March 2020. As of July 2021, the highest numbers of deaths are recorded in India, Indonesia, Iran, and Turkey, each with more than 90,000 deaths and more than 900,000 deaths combined. However, the death toll in Iran and Indonesia are claimed to be much higher than the official figures. Per capita, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Africa
The COVID-19 pandemicpandemic was confirmed to have spread to Africa on 14 February 2020, with the first confirmed case announced in Egypt. The first confirmed case in sub-Saharan Africa was announced in Nigeria at the end of February 2020. Within three months, the virus had spread throughout the continent, as Lesotho, the last African sovereign state to have remained free of the virus, reported a case on 13 May 2020. By 26 May, it appeared that most African countries were experiencing community transmission, although testing capacity was limited. Most of the identified imported cases arrived from Europe and the United States rather than from China where the virus originated. In early June 2021, Africa faced a third wave of COVID infections with cases rising in 14 countries. By 4 July the continent recorded more than 251,000 new Covid cases, a 20% increase from the prior week and a 12% increase from the January peak. More than sixteen African countries, including Malawi and S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Europe
The global COVID-19 pandemic arrived in Europe with its first confirmed case in Bordeaux, France, on 24 January 2020, and subsequently spread widely across the continent. By 17 March 2020, every country in Europe had confirmed a case, and all have reported at least one death, with the exception of Vatican City. Italy was the first European country to experience a major outbreak in early 2020, becoming the first country worldwide to introduce a national lockdown. By 13 March 2020, the World Health Organization (WHO) declared Europe the epicentre of the pandemic and it remained so until the WHO announced it was overtaken by South America on 22 May. By 18 March 2020, lockdowns introduced in Europe affected more than 250 million people. Despite deployment of COVID-19 vaccines, Europe became the pandemic's epicentre once again in late 2021. On 11 January 2022, Dr. Hans Kluge, the WHO Regional Director for Europe said, "more than 50 percent of the population in the region w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In South Africa
The COVID-19 pandemic in South Africa is part of the ongoing pandemic of coronavirus disease 2019 ( COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2). On 5 March 2020, Minister of Health Zweli Mkhize had confirmed the spread of the virus to South Africa, with the first known patient being a male citizen who tested positive upon his return from Italy. On 15 March 2020, the President of South Africa, Cyril Ramaphosa, declared a national state of disaster, and announced measures such as immediate travel restrictions and the closure of schools from 18 March. On 17 March, the ''National Coronavirus Command Council'' was established, "to lead the nation's plan to contain the spread and mitigate the negative impact of the coronavirus". On 23 March, a national lockdown was announced, starting on 27 March 2020. The first local death from the disease was reported on 27 March 2020. On 21 April, a 500 billion rand stimulus was announced in r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In The United Kingdom
The COVID-19 pandemic in the United Kingdom is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United Kingdom, it has resulted in confirmed cases, and is associated with deaths. The virus began circulating in the country in early 2020, arriving primarily from travel elsewhere in Europe. Various sectors responded, with more widespread public health measures incrementally introduced from March 2020. The first wave was at the time one of the world's largest outbreaks. By mid-April the peak had been passed and restrictions were gradually eased. A second wave, with a new variant that originated in the UK becoming dominant, began in the autumn and peaked in mid-January 2021, and was deadlier than the first. The UK started a COVID-19 vaccination programme in early December 2020. Generalised restrictions were gradually lifted and were mostly ended by August 2021. A third wave, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Fiji
The COVID-19 pandemic in Fiji is part of the ongoing worldwide pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The first case of the disease in Fiji was reported on 19 March 2020 in Lautoka. , the country has had a total of 55,009 cases as of which 2,417 are currently active and 702 deaths, with cases reported on all divisions of the country. Apart from the COVID-19 deaths, 621 COVID-19 positive patients have died from pre-existing non-COVID-19 related illnesses. In March 2021, Fiji became the first Pacific island country to receive COVID-19 vaccines through the COVAX initiative with frontline workers and first responders the first to be vaccinated. As of 2 January 2022, more than 600,000 (98%) Fijians have received their first jab of the vaccine and almost 560,000 (92%) Fijians have received their second jab and are fully vaccinated. To date, only the AstraZeneca vaccine, Moderna vaccine and the Pfizer BioNTech vaccine h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
