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Syndros
The International Nonproprietary Name Dronabinol, also known as delta-9-tetrahydrocannabinol, or under the trade names Marinol, Syndros, Reduvo and Adversa, is a generic name for the molecule of delta-9-tetrahydrocannabinol in the pharmaceutical context. It has indications as an appetite stimulant, antiemetic, and sleep apnea reliever and is approved by the FDA as safe and effective for HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting only. Dronabinol is the principal psychoactive constituent enantiomer form, (−)-''trans''-Δ9-tetrahydrocannabinol, found in cannabis. Dronabinol does not include any other tetrahydrocannabinol (THC) isomers or any cannabidiol. Medical uses Appetite stimulant and anti-emetic Dronabinol is used to stimulate appetite and therefore weight gain in patients with HIV/AIDS and cancer. It is also used to treat chemotherapy-induced nausea and vomiting. Analgesic Dronabinol demonstrated analgesic efficacy in a majority of stud ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetrahydrocannabinol
Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term ''THC'' usually refers to the Delta-9-THC isomer with chemical name (−)-''trans''-Δ9-tetrahydrocannabinol. THC is a lipid found in cannabis and, like most pharmacologically active secondary metabolites of plants, it is assumed to be involved in the plant's evolutionary adaptation, putatively against insect predation, ultraviolet light, and environmental stress. THC was first discovered and isolated by Israeli chemist Raphael Mechoulam in Israel in 1964. It was found that, when smoked, THC is absorbed into the bloodstream and travels to the brain, attaching itself to endocannabinoid receptors located in the cerebral cortex, cerebellum, and basal ganglia. These are the parts of the brain responsible for thinking, memory, pleasure, coordina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. Some antiemetics previously thought to cause birth defects appear safe for use by pregnant women in the treatment of morning sickness and the more serious hyperemesis gravidarum. __TOC__ Types * 5-HT3 receptor antagonists block serotonin receptors in the central nervous system and gastrointestinal tract. As such, they can be used to treat post-operative and cytotoxic drug nausea & vomiting. However, they can also cause constipation or diarrhea, dry mouth, and fatigue. ** Dolasetron (Anzemet) can be administered in tablet form or in an injection. ** Granisetron (Kytril, Sancuso) can be administered in tablet (Kytril), oral solution (Kytril), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Enforcement Administration
The Drug Enforcement Administration (DEA; ) is a Federal law enforcement in the United States, United States federal law enforcement agency under the U.S. Department of Justice tasked with combating drug trafficking and distribution within the U.S. It is the lead agency for domestic enforcement of the Controlled Substances Act, sharing concurrent jurisdiction with the Federal Bureau of Investigation, the U.S. Immigration and Customs Enforcement, and U.S. Customs and Border Protection although the DEA has sole responsibility for coordinating and pursuing U.S. drug investigations both domestically and abroad. The DEA has an DEA Office of National Security Intelligence, intelligence unit that is also a member of the United States Intelligence Community, U.S. Intelligence Community. While the unit is part of the DEA chain-of-command, it also reports to the Director of National Intelligence. History and mandate The Drug Enforcement Administration was established on July 1, 1973, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coalition For Rescheduling Cannabis
The Coalition for Rescheduling Cannabis is a U.S. organization founded c. 2002 to support removal of marijuana from Schedule I of the Controlled Substances Act. The group was organized immediately after the U.S. Court of Appeals denied the ''High Times''/Jon Gettman petition to reschedule cannabis, ruling that the petitioners were not sufficiently injured to have standing to challenge the Drug Enforcement Administration's interpretation of the scientific record in federal court. On October 8, 2002, the Coalition filed a new petition to have cannabis rescheduled under federal law. The Coalition has recently filed a Petition for Writ of Mandamus. Carl Olsen of Iowans for Medical Marijuana, a former Coalition member, has filed a motion to intervene. The organizations comprising the Coalition are: * American Alliance for Medical Cannabis * Americans for Safe Access *California NORML *Drug Policy Forum of Texas *Jon Gettman *''High Times'' * Los Angeles Cannabis Resource Center *Nati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jon Gettman
Jon B. Gettman (born August 20, 1957) is a marijuana rights activist, a leader of the Coalition for Rescheduling Cannabis, and a former head of the National Organization for the Reform of Marijuana Laws. He has a PhD in public policy and regional economic development from George Mason University and is a longtime contributor to ''High Times'' magazine. Gettman filed a petition in 1995 to remove cannabis from Schedule I of the Controlled Substances Act that was eventually denied. A second petition was filed in 2002, with the Coalition for Rescheduling Cannabis, that remains under review by the Department of Health and Human Services. Gettman frequently publishes on the marijuana industry and is an Associate Professor of Criminology and Criminal Justice at Shenandoah University in Virginia. Education Gettman received a BA in Anthropology from the Catholic University of America and a MS in Justice, specializing in drug policy, from American University. He holds a PhD in public poli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Removal Of Cannabis From Schedule I Of The Controlled Substances Act
In the United States, the removal of cannabis from Schedule I of the Controlled Substances Act is a proposed legal and administrative change in cannabis-related law at the federal level. It has been proposed repeatedly since 1972. The category is the most tightly restricted category reserved for drugs that have "no currently accepted medical use.” Background Schedule I is the only category of controlled substances not allowed to be prescribed by a physician. Under ', drugs must meet three criteria in order to be placed in Schedule I: # The drug or other substance has a high potential for abuse. # The drug or other substance has no currently accepted medical use in treatment in the United States. # There is a lack of accepted safety for use of the drug or other substance under medical supervision. In 1970, Congress placed cannabis into Schedule I on the advice of Assistant Secretary of Health Roger O. Egeberg. His letter to Harley O. Staggers, Chairman of the House Committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heroin
Heroin, also known as diacetylmorphine and diamorphine among other names, is a potent opioid mainly used as a recreational drug for its euphoric effects. Medical grade diamorphine is used as a pure hydrochloride salt. Various white and brown powders sold illegally around the world as heroin have variable "cuts". Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin. Heroin is used medically in several countries to relieve pain, such as during childbirth or a heart attack, as well as in opioid replacement therapy. It is typically injected, usually into a vein, but it can also be smoked, snorted, or inhaled. In a clinical context, the route of administration is most commonly intravenous injection; it may also be given by intramuscular or subcutaneous injection, as well as orally in the form of tablets. The onset of effects is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cocaine
Cocaine (from , from , ultimately from Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly used recreationally for its euphoric effects. It is primarily obtained from the leaves of two Coca species native to South America, '' Erythroxylum coca'' and '' Erythroxylum novogranatense''. After extraction from coca leaves and further processing into cocaine hydrochloride (powdered cocaine), the drug is often snorted, applied topically to the mouth, or dissolved and injected into a vein. It can also then be turned into free base form (crack cocaine), in which it can be heated until sublimated and then the vapours can be inhaled. Cocaine stimulates the reward pathway in the brain. Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. Physical effects may include a fast heart rate, sweating, and dilated pupils. High doses can result in high blood pressure or high body temperature. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Controlled Substances Act
The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated. It was passed by the 91st United States Congress as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970 and signed into law by President Richard Nixon. The Act also served as the national implementing legislation for the Single Convention on Narcotic Drugs. The legislation created five schedules (classifications), with varying qualifications for a substance to be included in each. Two federal agencies, the Drug Enforcement Administration (DEA) and the Food and Drug Administration (FDA), determine which substances are added to or removed from the various schedules, although the statute passed by Congress created the initial listing. Congress has sometimes scheduled other substances through legislation such as the Hillory J. Farias and Samantha Reid Date- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Psychoactive Drugs
The ''Journal of Psychoactive Drugs'' is a peer-reviewed medical journal on psychoactive drugs. It was established in 1967 by David E. Smith and is currently published five times per year by Taylor & Francis. It was previously titled ''Journal of Psychedelic Drugs'' until 1980. It was the first journal established in the United States to focus on psychoactive drug use, and continues to introduce groundbreaking work in topics such as drug use and criminality, therapeutic communities, dual diagnosis, psychotherapy/counseling, methadone maintenance treatment, and culturally-relevant substance abuse treatment. According to the ''Journal Citation Reports'', the journal has a 2016 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 1.740. References External links ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FAAAT
For Alternative Approaches to Addiction, Think & do tank (FAAAT or FAAAT think & do tank) is an international non-profit organization working on drug policy, created in 2015 and based in Paris, France. The organization focuses on research and advocacy related to policy alternatives in the field of addiction, drug use and substance abuse, claiming to foster civil society participation in policymaking at the international level. According to its mission statement, FAAAT supports "Transparent and measurable drug policies framed by fundamental rights, grounded on sustainable development, enforcing empowerment, social justice and health" and "supports the development of a legally controlled market for cannabis." The organization is present at both the local and international levels. Background FAAAT's vision is that, from the local up to the international level, public policies related to controlled drugs should be transparent and measurable, framed by the Fundamental human ri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
