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Splashed White
Splashed white or splash is a horse coat color pattern in the " overo" group of spotting patterns that produces pink-skinned, white markings. Many splashed whites have very modest markings, while others have the distinctive "dipped in white paint" pattern. Blue eyes are a hallmark of the pattern, and splash may account for otherwise "solid" blue-eyed horses. Splashed white occurs in a variety of geographically divergent breeds, from Morgans in North America to Kathiawari horses in India. The splashed white pattern is also associated with Hearing impairment, congenital deafness, though most splashed whites have normal hearing. Splashed white can be caused by multiple variants across two different genes, for which genetic testing is available. Characteristics The splashed white pattern is characterized by the appearance of having been dipped, feet-first, into white paint. Blue eyes An eye is a sensory organ that allows an organism to perceive visual information. It dete ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chestnut Splash White
The chestnuts are the deciduous trees and shrubs in the genus ''Castanea'', in the beech family Fagaceae. The name also refers to the edible nut (fruit), nuts they produce. They are native to temperate climate, temperate regions of the Northern Hemisphere. Description Chestnut trees are of moderate growth rate (for the Chinese chestnut tree) to fast-growing for American and European species. Their mature heights vary from the smallest species of chinkapins, often shrubby,''Chestnuts, Horse-Chestnuts, and Ohio Buckeyes'' . In Yard and Garden Brief, Horticulture department at University of Minnesota. to the giant of past American forests, ''American chestnut, C. dentata'' that could reach . Between these extremes are found the Japanese chestnut (''Castanea crenata, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cropout
A cropout, crop-out or crop out is a horse with body spots, including pinto or leopard complex spotting, or "high white" horse markings, with a sire and dam who both appeared to have been solid-colored. There are several variations in the definition, depending on the breed registry involved. There are multiple genetic reasons that may cause a horse to be a cropout. Sometimes solid-colored horses throw cropouts because some spotting patterns are recessive genes that are not necessarily expressed unless the relevant allele is inherited from both parents. Other times a gene may be a dominant or incomplete dominant but so minimally expressed that the horse looks solid but can pass flashy color on to its offspring. The term originally came about because excess white in certain breeds was considered an undesirable trait and such foals were deemed ineligible for registration, making them grade horses of little economic value. However, many people liked the flashy color, others sou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Finnhorse
The Finnhorse or Finnish Horse ( , literally "horse of Finland"; , literally "finnish cold-blood") is a horse breed with both riding horse and draught horse influences and characteristics, and is the only breed developed fully in Finland. In English it is sometimes called the Finnish Universal, as the Finns consider the breed capable of fulfilling all of Finland's horse needs, including agricultural and forestry work, harness racing, and riding. In 2007, the breed was declared the official national horse breed of Finland. The Finnhorse is claimed to be among the fastest and most versatile "coldblood" breeds in the world. In Finland, the term "universal horse" is used to describe the Finnhorse and breeds such as the Fjord horse that are relatively small with a body type that is heavy for a riding horse but light for a draught. There are four separate sections within the Finnhorse stud book, each with different goals: to develop a heavier working horse, a lighter trotter ty ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PAX3
The PAX3 (paired box gene 3) gene encodes a member of the paired box or Pax genes, PAX family of transcription factors. The PAX family consists of nine human (PAX1-PAX9) and nine mouse (Pax1-Pax9) members arranged into four subfamilies. Human PAX3 and mouse Pax3 are present in a subfamily along with the highly homologous human PAX7 and mouse Pax7 genes. The human PAX3 gene is located in the 2q36.1 chromosomal region, and contains 10 exons within a 100 kb region. Transcript splicing Alternative splicing and processing generates multiple PAX3 isoforms that have been detected at the mRNA level. PAX3e is the longest isoform and consists of 10 exons that encode a 505 amino acid protein. In other mammalian species, including mouse, the longest mRNAs correspond to the human PAX3c and PAX3d isoforms, which consist of the first 8 or 9 exons of the PAX3 gene, respectively. Shorter PAX3 isoforms include mRNAs that skip exon 8 (PAX3g and PAX3h) and mRNAs containing 4 or 5 exons (PAX3a and P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microphthalmia-associated Transcription Factor
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the ''MITF'' gene. MITF is a basic helix-loop-helix leucine zipper transcription factor involved in lineage-specific pathway regulation of many types of cells including melanocytes, osteoclasts, and mast cells. The term "lineage-specific", since it relates to MITF, means genes or traits that are only found in a certain cell type. Therefore, MITF may be involved in the rewiring of signaling cascades that are specifically required for the survival and physiological function of their normal cell precursors. MITF, together with transcription factor EB ( TFEB), TFE3 and TFEC, belong to a subfamily of related bHLHZip proteins, termed the MiT-TFE family of transcription factors. The factors are able to form stable DNA-binding homo- and heterodimers. The gene that encodes for MITF resides at the ''mi'' locus in mice, and its protu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reine De Since, Jument Splash White Overo
Reine is the administrative centre of Moskenes Municipality in Nordland county, Norway. The fishing village is located on the island of Moskenesøya in the Lofoten archipelago, above the Arctic Circle, about southwest of the city of Tromsø. Reine Church is located in the village. The village has a population (2023) of 297 and a population density of . The '' Lofotposten'' newspaper is published in Svolvær and it covers news all over Lofoten, including Moskenes Municipality. Overview Reine has been a trading post since 1743. It was also a centre for the local fishing industry with a fleet of boats and facilities for fish processing and marketing. There was also a little light industry. In December 1941, the Germans burnt part of Reine in reprisal for a raid on the Lofoten Islands by British troops. Today, tourism is important, and despite its remote location, many thousands of people visit annually. The village is situated on a promontory just off the European route E10 hig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brainstem Auditory Evoked Potentials
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the body back to the brai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Cell
Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates, and in the lateral line organ of fishes. Through mechanotransduction, hair cells detect movement in their environment. In mammals, the auditory hair cells are located within the spiral organ of Corti on the thin basilar membrane in the cochlea of the inner ear. They derive their name from the tufts of stereocilia called ''hair bundles'' that protrude from the apical surface of the cell into the fluid-filled cochlear duct. The stereocilia number from fifty to a hundred in each cell while being tightly packed together and decrease in size the further away they are located from the kinocilium. Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. Damage to these hair cells results in decreased hearing sensitivity, and because the inner ear hair cells cannot regenerate, this damag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanocyte
Melanocytes are melanin-producing neural-crest, neural crest-derived cell (biology), cells located in the bottom layer (the stratum basale) of the skin's epidermis (skin), epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart found in many mammals and birds. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against Ultraviolet, UV radiation. Melanocytes also have a role in the immune system. Function Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the human skin, skin, human eye, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Deafness
Hearing loss is a partial or total inability to hear. Hearing loss may be present at birth or acquired at any time afterwards. Hearing loss may occur in one or both ears. In children, hearing problems can affect the ability to acquire spoken language, and in adults it can create difficulties with social interaction and at work. Hearing loss can be temporary or permanent. Hearing loss related to age usually affects both ears and is due to cochlear hair cell loss. In some people, particularly older people, hearing loss can result in loneliness. Hearing loss may be caused by a number of factors, including: genetics, ageing, exposure to noise, some infections, birth complications, trauma to the ear, and certain medications or toxins. A common condition that results in hearing loss is chronic ear infections. Certain infections during pregnancy, such as cytomegalovirus, syphilis and rubella, may also cause hearing loss in the child. Hearing loss is diagnosed when hearing tes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
APHA Mare2
The acronym APHA may refer to: *American Paint Horse Association, a horse breed registry *American Pharmacists Association (APhA) *American Public Health Association ** APHA color, a color standard named for the American Public Health Association *Animal and Plant Health Agency The Animal and Plant Health Agency (APHA), formerly known as the Animal Health and Veterinary Laboratories Agency (AHVLA), is an executive agency of the Department for Environment, Food and Rural Affairs (Defra) of the United Kingdom. It was f ..., an executive agency of DEFRA, UK *'' Apha'', a genus of moths in the family Eupterotidae {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
