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Skinny Pig
The Skinny Pig or Skinny is an almost hairless strain of guinea pig. Skinny pigs typically have hair on their muzzles, feet, and legs, but are hairless over the remainder of their bodies. Some of them have a thin covering of fuzzy hair on their backs as well. The Skinny guinea pig is not one of the 13 recognized cavy breeds by the American Cavy Breeders Association. A healthy skinny has skin that is mostly smooth, with some wrinkling around the legs and neck. The body is full with no appearance of spine or ribs. Skinnies can come in a variety of skin colors and patterns, including "Dutch", "Brindle", and "Point coloration, Himalayan". The term ''skinny'' is used for hairless guinea pigs either because it colloquially refers to the exposed skin of the animal, or because it describes their thinner appearance due to their lack of hair. Unique traits The modern strain of skinny guinea pig originated from a cross between haired guinea pigs and a hairless Laboratory strain, lab stra ...
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Canada
Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of countries and dependencies by area, second-largest country by total area, with the List of countries by length of coastline, world's longest coastline. Its Canada–United States border, border with the United States is the world's longest international land border. The country is characterized by a wide range of both Temperature in Canada, meteorologic and Geography of Canada, geological regions. With Population of Canada, a population of over 41million people, it has widely varying population densities, with the majority residing in List of the largest population centres in Canada, urban areas and large areas of the country being sparsely populated. Canada's capital is Ottawa and List of census metropolitan areas and agglomerations in Canada, ...
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Thymus
The thymus (: thymuses or thymi) is a specialized primary lymphoid organ of the immune system. Within the thymus, T cells mature. T cells are critical to the adaptive immune system, where the body adapts to specific foreign invaders. The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. It is made up of two lobes, each consisting of a central medulla and an outer cortex, surrounded by a capsule. The thymus is made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. T cells that successfully develop react appropriately with Major histocompatibility complex, MHC immune receptors of the body (called ''positive selection'') and not against proteins of the body (called ''negative selection''). The thymus is the largest and most active during the neonatal and pre-adolescent periods. By the early teens, the Thymic involuti ...
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Naked Mole Rat
The naked mole-rat (''Heterocephalus glaber''), also known as the sand puppy, is a burrowing rodent native to the Horn of Africa and parts of Kenya, notably in Somali regions. It is closely related to the blesmols and is the only species in the genus ''Heterocephalus''. The naked mole-rat exhibits a highly unusual set of physiological and behavioral traits that allow it to thrive in a harsh underground environment; most notably its being the only mammalian thermoconformer with an almost entirely ectothermic (cold-blooded) form of body temperature regulation, as well as exhibiting eusociality, a complex social structure including a reproductive division of labor, separation of reproductive and non-reproductive castes, and cooperative care of young. The closely related Damaraland mole-rat (''Fukomys damarensis'') is the only other known eusocial mammal. Naked mole-rats lack pain sensitivity in their skin, and have very low metabolic and respiratory rates. The animal also is r ...
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Nude Mouse
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response. These xenografts are commonly used in research to test new methods of imaging and treating tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. Nomenclature The nomenclature for the nude mouse has changed several times since their discovery. Originally they were described as ''nu'' and this was updated to ''Hfh11nu'' when the mutated gene was identified as a mutation in the HNF-3/forkhead homolog 11 gene. Then in 2000, the gene responsible for the mutation was identified as a member of t ...
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Scandinavia
Scandinavia is a subregion#Europe, subregion of northern Europe, with strong historical, cultural, and linguistic ties between its constituent peoples. ''Scandinavia'' most commonly refers to Denmark, Norway, and Sweden. It can sometimes also refer to the Scandinavian Peninsula (which excludes Denmark but includes a part of northern Finland). In English usage, Scandinavia is sometimes used as a synonym for Nordic countries. Iceland and the Faroe Islands are sometimes included in Scandinavia for their Ethnolinguistics, ethnolinguistic relations with Sweden, Norway and Denmark. While Finland differs from other Nordic countries in this respect, some authors call it Scandinavian due to its economic and cultural similarities. The geography of the region is varied, from the Norwegian fjords in the west and Scandinavian mountains covering parts of Norway and Sweden, to the low and flat areas of Denmark in the south, as well as archipelagos and lakes in the east. Most of the population ...
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Caviinae
Caviinae is a subfamily uniting all living members of the family Caviidae with the exception of the maras, capybaras, and '' Kerodon''. The subfamily traditionally contained the guinea pig or cavy-like forms along with the cursorially adapted (running) ''Kerodon''. Molecular results suggest the Caviinae as so defined would be paraphyletic and ''Kerodon'' is more closely related to maras and capybaras than to other caviines.Rowe, D. L. and R. L. Honeycutt. 2002. Phylogenetic relationships, ecological correlates, and molecular evolution within the Cavioidea (Mammalia, Rodentia). Molecular Biology and Evolution, 19:263-277. This led Woods and Kilpatrick (2005) to unite ''Kerodon'' and capybaras into the subfamily Hydrochoerinae within the Caviidae. These studies also suggest '' Microcavia'' and ''Cavia'' are more closely related to one another than either is to '' Galea''. Genera and species *Subfamily Caviinae **†'' Cardiomys'' **†'' Allocavia'' **†'' Palaeocavia'' **†' ...
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Baldwin Guinea Pig
The Baldwin guinea pig is a breed developed from a spontaneous genetic mutation in Carol Miller's show-line of white crested golden agouti. Though born fully furred, Baldwin guinea pigs begin to lose their fur at two to five days of age, starting at the nose and leaving them almost entirely hairless by about two months of age. They retain whiskers and sometimes a few hairs on their feet. Baldwins are known for having skin of a rubbery texture, many wrinkles and large, droopy ears. They come in all colors and patterns that haired guinea pigs come in, such as Dutch, tortoiseshell, broken colors, Himalayan and selfs. Unique traits Hairless guinea pigs are not significantly physiologically different than regular haired guinea pigs, although they need to eat more to maintain body heat. The optimal temperature range for a hairless guinea pig is , which is slightly higher than the optimal temperature range for the haired guinea pig. Their skin has a similar appearance to human skin ...
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Recessive Gene
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and the second is called recessive. This state of having two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes ( autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, there are other forms of dominance, such as incomplete ...
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Werewolf
In folklore, a werewolf (), or occasionally lycanthrope (from Ancient Greek ), is an individual who can shapeshifting, shapeshift into a wolf, or especially in modern film, a Shapeshifting, therianthropic Hybrid beasts in folklore, hybrid wolf–humanlike creature, either purposely or after being placed under a curse or affliction, often a bite or the occasional scratch from another werewolf, with the transformations occurring on the night of a full moon. Early sources for belief in this ability or affliction, called lycanthropy, are Petronius (27–66) and Gervase of Tilbury (1150–1228). The werewolf is a widespread concept in European folklore, existing in many variants, which are related by a common development of a Christianization, Christian interpretation of underlying European folklore developed during the Middle Ages. From the early modern period, werewolf beliefs spread to the New World with colonialism. Belief in werewolves developed in parallel to the belief in Eu ...
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Outcrossing
Out-crossing or out-breeding is the technique of crossing between different breeds. This is the practice of introducing distantly related genetic material into a breeding line, thereby increasing genetic diversity. Outcrossing in animals Outcrossing can be a useful technique in animal breeding. The outcrossing breeder intends to remove the traits by using "new blood." With dominant traits, one can still see the expression of the traits and can remove those traits, whether one outcrosses, line breeds or inbreeds. With recessive traits, outcrossing allows for the recessive traits to migrate across a population. Many traits are Mendelian and therefore exhibit a more complicated intermediate phenotype. The outcrossing breeder then may have individuals that have many deleterious genes that may be expressed by subsequent inbreeding. There is now a gamut of deleterious genes within each individual in many dog breeds. Increasing the variation of genes or alleles within the gene poo ...
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USAMRIID
The United States Army Medical Research Institute of Infectious Diseases (USAMRIID; ) is the United States Army's main institution and facility for defensive research into countermeasures against biological warfare. It is located on Fort Detrick, Maryland, near Washington, D.C., and is a subordinate lab of the United States Army Medical Research and Development Command (USAMRDC), headquartered on the same installation. USAMRIID is the only laboratory of the United States Department of Defense (DoD) equipped to study highly hazardous viruses at Biosafety Level 4 within positive pressure personnel suits. USAMRIID employs both military and civilian scientists as well as highly specialized support personnel, totaling around 800 people. In the 1950s and 1960s, USAMRIID and its predecessor unit pioneered unique, state-of-the-art biocontainment facilities which it continues to maintain and upgrade. Investigators at its facilities frequently collaborate with the Centers for Disea ...
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