Rhadinovirus
''Rhadinovirus'' (synonyms: ''Rhadinoviridae'' and gamma-2 herpesviruses) is a genus of viruses in the order '' Herpesvirales'', in the family '' Herpesviridae'', in the subfamily '' Gammaherpesvirinae''. Humans and other mammals serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, caused by '' Human gammaherpesvirus 8'' (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). The term rhadino comes from the Latin fragile, referring to the tendency of the viral genome to break apart when it is isolated. Species The genus consists of the following 12 species: * ''Ateline gammaherpesvirus 2'' * ''Ateline gammaherpesvirus 3'' * ''Bovine gammaherpesvirus 4'' * ''Cricetid gammaherpesvirus 2'' * '' Human gammaherpesvirus 8'' * ''Macacine gammaherpesvirus 5'' * ''Macacine gammaherpesvirus 8'' * ''Macacine gammaherpesvirus 11'' * ''Mac ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Human Gammaherpesvirus 8
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is ''Human gammaherpesvirus 8'', or HHV-8 in short. Like other herpesviruses, its informal names are used interchangeably with its formal ICTV name. This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients, as well as primary effusion lymphoma, HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome. It is one of seven currently known human cancer viruses, or oncoviruses. Even after so many years of discovery of KSHV/HHV8, there is no known cure for KSHV associated tumorigenesis. History In 1872, Moritz Kaposi described a blood vessel tumor (originally called "idiopathic multiple pigmented sarcoma of the skin") that has since been eponymously named Kaposi's sarcoma (KS). KS was at first thought to be an uncommon tumor of Jewish and Mediterranean popul ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery w ... of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is ofte ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Macacine Gammaherpesvirus 8
''Macacine gammaherpesvirus 8'' (McHV-8) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Squirrel Monkey
Squirrel monkeys are New World monkeys of the genus ''Saimiri''. ''Saimiri'' is the only genus in the subfamily Saimirinae. The name of the genus is of Tupi origin (''sai-mirím'' or ''çai-mbirín'', with ''sai'' meaning 'monkey' and ''mirím'' meaning 'small') and was also used as an English name by early researchers. Squirrel monkeys live in the tropical forests of Central and South America in the canopy layer. Most species have parapatric or allopatric ranges in the Amazon, while ''S. oerstedii'' is found disjunctly in Costa Rica and Panama. There are two main groups of squirrel monkeys recognized. They are differentiated based on the shape of the white coloration above the eyes. In total there are 5 recognized species. Squirrel monkeys have short and close fur colored black at the shoulders, yellow or orange fur along the back and extremities, and white on the face. Squirrel monkeys have determined breeding seasons which involve large fluctuations in hormones and there ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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New World Monkey
New World monkeys are the five families of primates that are found in the tropical regions of Mexico, Central and South America: Callitrichidae, Cebidae, Aotidae, Pitheciidae, and Atelidae. The five families are ranked together as the Ceboidea (), the only extant superfamily in the parvorder Platyrrhini (). Platyrrhini is derived from the Greek for "broad nosed", and their noses are flatter than those of other simians, with sideways-facing nostrils. Monkeys in the family Atelidae, such as the spider monkey, are the only primates to have prehensile tails. New World monkeys' closest relatives are the other simians, the Catarrhini ("down-nosed"), comprising Old World monkeys and apes. New World monkeys descend from African simians that colonized South America, a line that split off about 40 million years ago. Evolutionary history About 40 million years ago, the Simiiformes infraorder split into the parvorders Platyrrhini (New World monkeys) and Catarrhini ( apes and O ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fibroblast
A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, produces the structural framework ( stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals. Structure Fibroblasts have a branched cytoplasm surrounding an elliptical, speckled nucleus having two or more nucleoli. Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum. Inactive fibroblasts (called fibrocytes) are smaller, spindle-shaped, and have a reduced amount of rough endoplasmic reticulum. Although disjointed and scattered when they have to cover a large space, fibroblasts, when crowded, often locally align in parallel clusters. Unlike the epithelial cells lining the body structures, fibroblasts do not form flat monolayers and are not restricted by a polarizing attachment to a basal lamina on one side, although they may contribute to basal lamina components in so ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Saimiriine Gammaherpesvirus 2
''Saimiriine gammaherpesvirus 2'' (SaHV-2) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales''. See also * HSUR (''Herpesvirus saimiri'' U RNAs) * Squirrel monkey Squirrel monkeys are New World monkeys of the genus ''Saimiri''. ''Saimiri'' is the only genus in the subfamily Saimirinae. The name of the genus is of Tupi origin (''sai-mirím'' or ''çai-mbirín'', with ''sai'' meaning 'monkey' and ''mirím'' ... (''Saimiri'') References External links * Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Murid Gammaherpesvirus 7
''Murid gammaherpesvirus 7'' is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Murid Gammaherpesvirus 4
''Murid gammaherpesvirus 4'' (MuHV-4) is a species of virus in the genus ''Rhadinovirus''. It is a member of the subfamily ''Gammaherpesvirinae'' in the family ''Herpesviridae''. This species infects mice via the nasal passages and causes an acute infectious mononucleosis-like syndrome with elevated levels of leukocytes, and shifts in the relative proportion of lymphocytes along with the appearance of atypical mononuclear cells. ''Murid gammaherpesvirus 4'' currently serves as a model for study of human gammaherpesvirus pathogenesis Pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. The word comes from Greek πάθος ''pat .... Strains Seven strains of ''Murid gammaherpesvirus 4'' have been isolated, including the following six: * MuHV-Šum * MuHV-60 * MuHV-68 * MuHV-72 * MuHV-76 * MuHV-4556 References {{Taxon ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Macacine Gammaherpesvirus 12
''Macacine gammaherpesvirus 12'' (McHV-12) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Macacine Gammaherpesvirus 11
''Macacine gammaherpesvirus 11'' (McHV-11) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cricetid Gammaherpesvirus 2
''Cricetid gammaherpesvirus 2'' (CrHV-2) is a species of virus in the genus ''Rhadinovirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References Gammaherpesvirinae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |