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Revaxis
The DPT vaccine or DTP vaccine is a class of combination vaccines to protect against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus (lockjaw). The vaccine components include diphtheria and tetanus toxoids, and either killed whole cells of the bacterium that causes pertussis or pertussis antigens. The term toxoid refers to vaccines which use an inactivated toxin produced by the pathogen which they are targeted against to generate an immune response. In this way, the toxoid vaccine generates an immune response which is targeted against the toxin which is produced by the pathogen and causes disease, rather than a vaccine which is targeted against the pathogen itself. The whole cells or antigens will be depicted as either "DTwP" or "DTaP", where the lower-case "w" indicates whole-cell inactivated pertussis and the lower-case "a" stands for "acellular". In comparison to alternative vaccine types, such as live attenuated vaccines, the DTP ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and recognize further and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or alleviate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer). Some vaccines offer full sterilizing immunity, in which infection is prevented. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Side Effects
In medicine, a side effect is an effect of the use of a medicinal drug or other treatment, usually adverse but sometimes beneficial, that is unintended. Herbal and traditional medicines also have side effects. A drug or procedure usually used for a specific effect may be used specifically because of a beneficial side-effect; this is termed " off-label use" until such use is approved. For instance, X-rays have long been used as an imaging technique; the discovery of their oncolytic capability led to their use in radiotherapy for ablation of malignant tumours. Frequency of side effects The World Health Organization and other health organisations characterise the probability of experiencing side effects as: * Very common, ≥ 1⁄10 * Common (frequent), 1⁄10 to 1⁄100 * Uncommon (infrequent), 1⁄100 to 1⁄1000 * Rare, 1⁄1000 to 1⁄10000 * Very rare, < 1⁄10000 The |
DTwP-HepB-Hib Vaccine
DTwP-HepB-Hib vaccine is a 5-in-1 combination vaccine with five individual vaccines conjugated into one. It protects against diphtheria, tetanus, whooping cough, hepatitis B and ''Haemophilus influenzae'' type B, which is generally used in middle- and low-income countries, where polio vaccine is given separately. By 2013, pentavalent vaccines accounted for 100% of the DTP-containing vaccines procured by UNICEF, which supplies vaccines to a large proportion of the world's children. Safety During studies and tests, the conjugated liquid DTPw- HepB- Hib vaccine was found to have positive safety when given as a booster to young children who have been given a vaccination course with another pentavalent booster that requires a change in constitution and was also found to be adequately immunogenic. History In October 2004, the European Medicines Agency granted marketing approval to the pentavalent vaccine Quintanrix, manufactured by GlaxoSmithKline. Quintanrix was voluntarily ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preventive Healthcare
Preventive healthcare, or prophylaxis, is the application of healthcare measures to prevent diseases.Hugh R. Leavell and E. Gurney Clark as "the science and art of preventing disease, prolonging life, and promoting physical and mental health and efficiency. Leavell, H. R., & Clark, E. G. (1979). Preventive Medicine for the Doctor in his Community (3rd ed.). Huntington, NY: Robert E. Krieger Publishing Company. Disease and disability are affected by environmental factors, genetic predisposition, disease agents, and Lifestyle disease, lifestyle choices, and are dynamic processes that begin before individuals realize they are affected. Disease prevention relies on anticipatory actions that can be categorized as primal, primary, secondary, and tertiary prevention. Each year, millions of people die of preventable causes. A 2004 study showed that about half of all deaths in the United States in 2000 were due to preventable behaviors and exposures. Leading causes included cardiovascul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Immunization Technical Advisory Group
National Immunization Technical Advisory Group (NITAG) is an advisory committee composed of multidisciplinary experts responsible for providing information to national governments. This information is used to make evidence-based decisions regarding vaccines and immunization policies. The majority of industrialized countries, as well as some developing countries, have formally established advisory committees to guide their immunization policies, while other countries are working towards establishing such committees. Purpose The primary purpose of a NITAG is to provide technical expertise by offering guidance and recommendations to national policymakers and program managers, enabling them to make evidence-based decisions regarding immunization policies and programs. This may also include recommendations on vaccination schedules, such as the appropriate timing, dosage, and contraindications of vaccines. To ensure that the government gives proper attention to NITAG recommendations, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Advisory Committee On Immunization Practices
The Advisory Committee on Immunization Practices (ACIP) is a National Immunization Technical Advisory Group, committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control of vaccine-preventable diseases in the U.S. civilian population. The ACIP develops written recommendations for routine administration of vaccines to the pediatric and adult populations, along with vaccination schedules regarding appropriate timing, dosage, and contraindications of vaccines. ACIP statements are official federal recommendations for using vaccines and immune globulins in the U.S. and are published by the CDC. ACIP reports directly to the CDC director, although its management and support services are provided by the CDC's National Center for Immunization and Respiratory Diseases. Purpose and Impact The ACIP was established in March 1964 by the US Surgeon General to assist in preventing and controlling communicable diseases, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pertussis Vaccine
Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). There are two main types: whole-cell vaccines and acellular vaccines. The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective. The effectiveness of the vaccines appears to decrease by between 2 and 10% per year after vaccination, with a more rapid decrease with the acellular vaccines. The vaccine is only available in combination with tetanus and diphtheria vaccines (DPT vaccine). Pertussis vaccine is estimated to have saved over 500,000 lives in 2002. Vaccinating the mother during pregnancy may protect the baby. The World Health Organization and the US Centers for Disease Control and Prevention recommend all children be vaccinated for pertussis and that it be included in Vaccination schedule, routine vaccinations. Three doses starting at six weeks of age are typically recommended in young children. Additional doses may be given to older children and adults. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whole-cell Vaccine
Whole-cell vaccines are a type of vaccine that has been prepared in the laboratory from entire cells. Such vaccines simultaneously contain multiple antigens to activate the immune system. They induce antigen-specific T-cell responses. Whole-cell vaccines have been researched in the fields of bacterial infectious disease (as an inactivated vaccine) and cancer (as tumor cells modified to stimulate the immune system by secreting stimulatory molecules). One whole-cell vaccine that sees global use is the whole-cell pertussis vaccine. Against infectious disease Pertussis The causative organism of pertussis is '' Bordetella pertussis''. The whole-cell pertussis vaccine is effective and safe in treating this disease but is also associated with short-term side effects. Depending upon the different ''B. pertussis'' antigens, the immune response produced by the whole-cell vaccine also varies. The pertussis whole-cell vaccine contains inactivated bacterial cells that contain antigens l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (biology)
The cell is the basic structural and functional unit of all life, forms of life. Every cell consists of cytoplasm enclosed within a Cell membrane, membrane; many cells contain organelles, each with a specific function. The term comes from the Latin word meaning 'small room'. Most cells are only visible under a light microscope, microscope. Cells Abiogenesis, emerged on Earth about 4 billion years ago. All cells are capable of Self-replication, replication, protein synthesis, and cell motility, motility. Cells are broadly categorized into two types: eukaryotic cells, which possess a Cell nucleus, nucleus, and prokaryotic, prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular organism, multicellular, such as some algae, plants, animals, and fungi. Eukaryotic cells contain organelles including Mitochondrion, mitochondria, which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proxy (statistics)
In statistics, a proxy or proxy variable is a variable that is not in itself directly relevant, but that serves in place of an unobservable or immeasurable variable. In order for a variable to be a good proxy, it must have a close correlation, not necessarily linear, with the variable of interest. This correlation might be either positive or negative. Proxy variable must relate to an unobserved variable, must correlate with disturbance, and must not correlate with regressors once the disturbance is controlled for. Examples In social sciences, proxy measurements are often required to stand in for variables that cannot be directly measured. This process of standing in is also known as operationalization. Per-capita gross domestic product (GDP) is often used as a proxy for measures of standard of living or quality of life. Montgomery ''et al.'' examine several proxies used, and point out limitations with each, stating "In poor countries, no single empirical measure can be expected ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has 6 regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level. The WHO's purpose is to achieve the highest possible level of health for all the world's people, defining health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." The main functions of the World Health Organization include promoting the control of epidemic and endemic diseases; providing and improving the teaching and training in public health, the medical treatment of disease, and related matters; and promoting the establishment of international standards for biologic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
