Prenylflavonoid
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Prenylflavonoid
Prenylated flavonoids or prenylflavonoids are a sub-class of flavonoids. They are widely distributed throughout the plant kingdom. Some are known to have phytoestrogenic or antioxidant properties. They are given in the list of adaptogens in herbalism. Chemically they have a prenyl group attached to their flavonoid backbone. It is usually assumed that the addition of hydrophobic prenyl groups facilitate attachment to cell membranes. Prenylation may increase the potential activity of its original flavonoid. Monoprenyl isoflavone epoxidase is a key enzyme in fungal ''Botrytis cinerea'' metabolism of prenylated flavonoids. Many prenylflavonoids appear to have anticancer activity in vitro. Prenylchalcones, prenylflavones, prenylflavonols and prenylflavanones are classes of prenylflavonoids. Examples 6-Prenylnaringenin, 6-geranylnaringenin, 8-prenylnaringenin and isoxanthohumol can be found in hops and beer. Of the prenylflavonoids, 8-prenylnaringenin is the most potent phytoes ...
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Cannflavin
Cannflavins are a group of chemical compounds found in ''Cannabis sativa''. Chemically, they are prenylflavonoids and are unrelated to THC and other cannabinoids. Cannflavins A and B were first identified in the 1980s and cannflavin C was identified in 2008. Because cannflavins A and B are inhibitors of prostaglandin E2 production ''in vitro'', the cannflavins have been studied for their potential use as anti-inflammatory agents. Biosynthesis Cannflavins A and B are biosynthesized by prenylation of chrysoeriol Chrysoeriol is a flavone, chemically the 3'-methoxy derivative of luteolin. Related compounds Diosmetin is one of three possible regioisomer In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compo .... References {{reflist Prenylflavonoids ...
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