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Phenolphthalein
Phenolphthalein ( ) is a chemical compound with the formula C20 H14 O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in acid–base titrations. For this application, it turns colorless in acidic solutions and pink in basic solutions. It belongs to the class of dyes known as phthalein dyes. Phenolphthalein is slightly soluble in water and usually is dissolved in alcohols for use in experiments. It is a weak acid, which can lose H+ ions in solution. The nonionized phenolphthalein molecule is colorless and the double deprotonated phenolphthalein ion is fuchsia. Further loss of proton in higher pH occurs slowly and leads to a colorless form. Phenolphthalein ion in concentrated sulfuric acid is orange red due to sulfonation. Uses pH indicator Phenolphthalein's common use is as an indicator in acid-base titrations. It also serves as a component of universal indicator, together with methyl red ...
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Phenolphthalein Reaction
Phenolphthalein ( ) is a chemical compound with the formula C20 H14 O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in acid–base titrations. For this application, it turns colorless in acidic solutions and pink in basic solutions. It belongs to the class of dyes known as phthalein dyes. Phenolphthalein is slightly soluble in water and usually is dissolved in alcohols for use in experiments. It is a weak acid, which can lose H+ ions in solution. The nonionized phenolphthalein molecule is colorless and the double deprotonated phenolphthalein ion is fuchsia. Further loss of proton in higher pH occurs slowly and leads to a colorless form. Phenolphthalein ion in concentrated sulfuric acid is orange red due to sulfonation. Uses pH indicator Phenolphthalein's common use is as an indicator in acid-base titrations. It also serves as a component of universal indicator, together with methyl red, b ...
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Phenolsulfonphthalein
Phenol red (also known as phenolsulfonphthalein or PSP) is a pH indicator frequently used in cell biology laboratories. Chemical structure and properties Phenol red exists as a red crystal that is stable in air. Its solubility is 0.77 grams per liter (g/L) in water and 2.9 g/L in ethanol.''Merck Index'', 11th ed., 7213 Phenolsulfonphtalein It is a weak acid with p''K''a = 8.00 at . A solution of phenol red is used as a pH indicator, often in cell culture. Its color exhibits a gradual transition from yellow ( λmax = 443 nm) to red (λmax = 570 nm) over the pH range 6.8 to 8.2. Above pH 8.2, phenol red turns a bright pink (fuchsia) color.''Merck Index'', 13th ed., 7329 PhenolsulfonphthaleinBeilstein 5-19-03-00457 In crystalline form, and in solution under very acidic conditions (low pH), the compound exists as a zwitterion as in the structure shown above, with the sulfate group negatively charged, and the ketone group carrying an additional proton. This form is ...
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Universal Indicator
__FORCETOC__ A universal indicator is a pH indicator made of a solution of several compounds that exhibits several smooth colour changes over a wide range pH values to indicate the acidity or alkalinity of solutions. Although there are several commercially available universal pH indicators, most are a variation of a formula patented by Yamada in 1933. Details of this patent can be found in ''Chemical Abstracts''. Experiments with Yamada's universal indicator are also described in the ''Journal of Chemical Education''. A universal indicator is usually composed of water, 1-propanol, phenolphthalein, sodium hydroxide, methyl red, bromothymol blue, sodium bisulfite, and thymol blue. The colours that indicate the pH of a solution, after adding a universal indicator, are The colours from yellow to red indicate an acidic solution, colours blue to violet indicate an alkaline solution and a green colour indicates that a solution is neutral. Wide-range pH test papers with distinc ...
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Phthalein Dyes
Phthalein dyes are a class of dyes mainly used as pH indicators, due to their ability to change colors depending on pH. They are formed by the reaction of phthalic anhydride with various phenols. They are a subclass of triarylmethane dyes. Common phthalein dyes include: *Bromothymol blue *Bromocresol green *Bromocresol purple * Cresol Red * ''o''-Cresolphthalein * Chlorophenol red * Dixylenolphthalein * Guaiacolphthalein * α-Naphtholphthalein * Phenolphthalein * Phenolsulfonphthalein * Tetrabromophenolphthalein * Thymol blue * Thymolphthalein * Xylenolphthalein See also *Triarylmethane dye Triarylmethane dyes are synthetic organic compounds containing triphenylmethane backbones. As dyes, these compounds are intensely colored. They are produced industrially as dyes. Families Triarylmethane dyes can be grouped into families accordin ... References Triarylmethane dyes Phthalides {{organic-compound-stub ...
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Acid–base Titration
An acid–base titration is a method of quantitative analysis for determining the concentration of an acid or base by exactly neutralizing it with a standard solution of base or acid having known concentration. A pH indicator is used to monitor the progress of the acid–base reaction. If the acid dissociation constant (p''K''a) of the acid or base dissociation constant (p''K''b) of base in the analyte solution is known, its solution concentration (molarity) can be determined. Alternately, the p''K''a can be determined if the analyte solution has a known solution concentration by constructing a titration curve. Alkalimetry and acidimetry Alkalimetry and acidimetry are a kind of volumetric analysis in which the fundamental reaction is a neutralization reaction. Acidimetry is the specialized analytic use of acid-base titration to determine the concentration of a basic (synonymous to alkaline) substances using standard acid. Alkalimetry, is the same concept of specialized analyt ...
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Base (chemistry)
In chemistry, there are three definitions in common use of the word base, known as Arrhenius bases, Brønsted bases, and Lewis bases. All definitions agree that bases are substances that react with acids, as originally proposed by G.-F. Rouelle in the mid-18th century. In 1884, Svante Arrhenius proposed that a base is a substance which dissociates in aqueous solution to form Hydroxide ions OH−. These ions can react with hydrogen ions (H+ according to Arrhenius) from the dissociation of acids to form water in an acid–base reaction. A base was therefore a metal hydroxide such as NaOH or Ca(OH)2. Such aqueous hydroxide solutions were also described by certain characteristic properties. They are slippery to the touch, can taste bitter and change the color of pH indicators (e.g., turn red litmus paper blue). In water, by altering the autoionization equilibrium, bases yield solutions in which the hydrogen ion activity is lower than it is in pure water, i.e., the water ...
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