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Princess Imoukhuede
Princess Imoukhuede (pronounced I-muh-KWU-e-de) (born 1980) is an American chemical engineer who is a Professor in Bioengineering at the University of Washington as the Hunter and Dorthy Simpson Endowed Chair. She conducts groundbreaking research on angiogenic signaling and vascular biology. Her lab employs quantitative systems biology to understand and control signaling networks driving blood-vessel formation, with the aim of developing treatments for diseases like cancer and cardiovascular disorders. Imoukhuede's work has earned her numerous awards, including the National Science Foundation CAREER Award and the Biomedical Engineering Society Mid-Career Award, and the Illinois Mathematics and Science Academy Distinguished Leadership Award and the 2018 Nano Research Young Innovators Award in Nanobiotechnology, recognizing her significant contributions to scholarship, education, and mentorship. Her first name is 'Princess' however, she holds no royal title or position in any capaci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Washington University In St
Washington most commonly refers to: * George Washington (1732–1799), the first president of the United States * Washington (state), a state in the Pacific Northwest of the United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on Washington, D.C. Washington may also refer to: Places England * Washington Old Hall, ancestral home of the family of George Washington * Washington, Tyne and Wear, a town in the City of Sunderland metropolitan borough * Washington, West Sussex, a village and civil parish Greenland * Cape Washington, Greenland * Washington Land Philippines *New Washington, Aklan, a municipality *Washington, a barangay in Catarman, Northern Samar *Washington, a barangay in Escalante, Negros Occidental *Washington, a barangay in San Jacinto, Masbate *Washington, a barangay in Surigao City United States * Fort Washington (disambiguati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Track And Field
Track and field (or athletics in British English) is a sport that includes Competition#Sports, athletic contests based on running, jumping, and throwing skills. The name used in North America is derived from where the sport takes place, a running track and a grass field for the throwing and some of the jumping events. Track and field is categorized under the umbrella sport of athletics, which also includes road running, cross country running and racewalking. Though the sense of "athletics" as a broader sport is not used in American English, outside of the United States the term ''athletics'' can either be used to mean just its track and field component or the entirety of the sport (adding road racing and cross country) based on context. The foot racing events, which include sprint (running), sprints, middle-distance running, middle- and long-distance running, long-distance events, racewalking, and hurdling, are won by the athlete who completes it in the least time. The jumpin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarah K
Sarah (born Sarai) is a biblical matriarch, prophet, and major figure in Abrahamic religions. While different Abrahamic faiths portray her differently, Judaism, Christianity, and Islam all depict her character similarly, as that of a pious woman, renowned for her hospitality and beauty, the wife of Abraham, and the mother of Isaac. Sarah has her feast day on 1 September in the Catholic Church, 19 August in the Coptic Orthodox Church, 20 January in the LCMS, and 12 and 20 December in the Eastern Orthodox Church. In the Hebrew Bible Family According to Book of Genesis 20:12, in conversation with the Philistine king Abimelech of Gerar, Abraham describes Sarah as both his wife and his half-sister ("my father's daughter, but not my mother's"). Such unions were later explicitly banned in the Book of Leviticus (). However, some commentators identify her as Iscah (Genesis 11:29), a daughter of Abraham's brother Haran.Schwartz, Howard, (1998). ''Reimagining the Bible: The Storytellin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Platelet-derived Growth Factor Receptor
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF subunits -A and -B are important factors regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including cancer. There are two forms of the PDGF-R, alpha and beta each encoded by a different gene. Depending on which growth factor is bound, PDGF-R homo- or heterodimerizes. Mechanism of action The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or hetero dimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. The extracellular region of the receptor consists of five immunoglobulin-like dom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VEGF Receptor
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending on alternative splicing, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR). Inhibitors of VEGFR are used in the treatment of cancer. VEGF Vascular endothelial growth factor (VEGF) is an important signaling protein involved in both vasculogenesis (the formation of the circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). As its name implies, VEGF activity is restricted mainly to cells of the vascular endothelium, although it does have effects on a limited number of other cell types (e.g. stimulation monocyte/macrophage migration). ''In vitro'', VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF also enhances microvascular permeability and is sometimes referred to as vascular permeability factor. Receptor biology All members of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrosine Kinase Receptor
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Mutations in receptor tyrosine kinases lead to activation of a series of signalling cascades which have numerous effects on protein expression. The receptors are generally activated by dimerization and substrate presentation. Receptor tyrosine kinases are part of the larger family of protein tyrosine kinases, encompassing the receptor tyrosine kinase proteins which contain a transmembrane domain, as well as the non-receptor tyrosine kinases which do not possess transmembrane domains. History The first RTKs to be discovered were the EG ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vascular Endothelial Growth Factor
Vascular endothelial growth factor (VEGF, ), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of Cystine knot, cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the ''De novo synthesis, de novo'' formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate such as in hypoxic conditions. Serum concentration of VEGF is high in bronchial asthma and diabetes mellitus. VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoc
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. According to data from the US National Science Foundation, the number of holders of PhD in biological sciences who end up in tenure track has consistently dropped from over 50% in 1973 to less than 20% in 2006. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caltech
The California Institute of Technology (branded as Caltech) is a private university, private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of Institute of Technology (United States), institutes of technology in the United States that are devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery Hale, Arthur Amos Noyes, and Robert Andrews Millikan in the early 20th century. The vocational and preparatory schools were disbanded and spun off in 1910, and the college assumed its present name in 1920. In 1934, Caltech was elected to the Association of American Universities, and the antecedents of NASA's Jet Propulsion Laboratory, which Caltech continues to manage and operate, were established between 1936 and 1943 under ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Förster Resonance Energy Transfer
Förster resonance energy transfer (FRET), fluorescence resonance energy transfer, resonance energy transfer (RET) or electronic energy transfer (EET) is a mechanism describing energy transfer between two light-sensitive molecules (chromophores). A donor chromophore, initially in its electronic excited state, may transfer energy to an acceptor chromophore through nonradiative dipole–dipole coupling. The efficiency of this energy transfer is inversely proportional to the sixth power of the distance between donor and acceptor, making FRET extremely sensitive to small changes in distance. Measurements of FRET efficiency can be used to determine if two fluorophores are within a certain distance of each other. Such measurements are used as a research tool in fields including biology and chemistry. FRET is analogous to Near and far field, near-field communication, in that the radius of interaction is much smaller than the Light, wavelength of light emitted. In the near-field region, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GABA Transporter
GABA transporters (gamma-aminobutyric acid Neurotransmitter transporter, transporters) are a family of neurotransmitter / sodium Symporter, symporters, belonging to the Solute carrier family, solute carrier 6 (SLC6) family. They are found in various regions of the brain in different cell types, such as neurons and astrocytes. These transporters are primarily responsible for the regulation of extracellular GABA concentration during basal and synaptic activity. They are responsible for creating a GABA gradient which is determined by the membrane potential, and the concentration of Na+ and Cl−. They are also present on the plasma membrane of neurons and glia which help define their function of regulation of GABA concentration as they act as the receptors that facilitate recycling of GABA in the extracellular space. GABA transporters are a common target for anticonvulsant drugs against seizure disorders such as epilepsy. Types The GABA transporter group consists of six different tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Collegiate Athletic Association
The National Collegiate Athletic Association (NCAA) is a nonprofit organization that regulates College athletics in the United States, student athletics among about 1,100 schools in the United States, and Simon Fraser University, 1 in Canada. It also organizes the Athletics (physical culture), athletic programs of colleges and helps over 500,000 college student athletes who compete annually in college sports. The headquarters is located in Indianapolis, Indiana. Until the 1956–57 academic year, the NCAA was a single division for all schools. That year, the NCAA split into the NCAA University Division, University Division and the NCAA College Division, College Division. In August 1973, the current three-division system of NCAA Division I, Division I, NCAA Division II, Division II, and NCAA Division III, Division III was adopted by the NCAA membership in a special convention. Under NCAA rules, Division I and Division II schools can offer athletic scholarships to students. Divi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
