|
PLHIV
HIV-positive people, seropositive people or people who live with HIV are people infected with the human immunodeficiency virus (HIV), a retrovirus which if untreated may progress to acquired immunodeficiency syndrome (AIDS). According to estimates by the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS), 38.4 million people were infected with HIV at the end of 2021. That same year, some 1.5 million people became newly infected, and 650,000 died of AIDS-related causes, including 98,000 children. More than two-thirds of new HIV infections are in sub-Saharan Africa. Testing and awareness Infection with HIV is determined by an HIV test. As of 2021, 85% of all people living with HIV knew their status. The Joint United Nations Program on HIV/AIDS (UNAIDS), Amnesty International, the Global Network of Sex Work Projects and the Global Network of People Living with HIV/AIDS, have all condemned forced HIV testing actions as infringements on hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serophobia
Discrimination against people with HIV/AIDS or serophobia is the prejudice, fear, rejection, and stigmatization of people with HIV/AIDS ( PLHIV people living with HIV/AIDS). Marginalized, at-risk groups such as members of the LGBTQ+ community, intravenous drug users, and sex workers are most vulnerable to facing HIV/AIDS discrimination. The consequences of societal stigma against PLHIV are quite severe, as HIV/AIDS discrimination actively hinders access to HIV/AIDS screening and care around the world. Moreover, these negative stigmas become used against members of the LGBTQ+ community in the form of stereotypes held by physicians. HIV/AIDS discrimination takes many forms such as blood donation restrictions on at-risk populations, compulsory HIV testing without prior consent, violations of confidentiality within healthcare settings, and targeted violence against persons living with HIV. While current conversations tend to center around HIV/AIDS in the United States, the disease is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People With HIV/AIDS
HIV-positive people, seropositive people or people who live with HIV are people infected with the human immunodeficiency virus (HIV), a retrovirus which if untreated may progress to acquired immunodeficiency syndrome (AIDS). According to estimates by the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS), 38.4 million people were infected with HIV at the end of 2021. That same year, some 1.5 million people became newly infected, and 650,000 died of AIDS-related causes, including 98,000 children. More than two-thirds of new HIV infections are in sub-Saharan Africa. Testing and awareness Infection with HIV is determined by an HIV test. As of 2021, 85% of all people living with HIV knew their status. The Joint United Nations Program on HIV/AIDS (UNAIDS), Amnesty International, the Global Network of Sex Work Projects and the Global Network of People Living with HIV/AIDS, have all condemned forced HIV testing actions as infringements ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cell Transplant
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells. HSCT may be autologous (the patient's own stem cells are used), syngeneic (stem cells from an identical twin), or allogeneic (stem cells from a donor). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma, leukemia, some types of lymphoma and immune deficiencies. In these cases, the recipient's immune system is usually suppressed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serostatus
Serostatus refers to the presence or absence of a serological Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given mi ... marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity. HIV/AIDS The term serostatus is commonly used in HIV/AIDS prevention efforts. In the late 20th and early 21st centuries, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease. Autoimmune disease Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation. Study of seronegative patient populations has led to the identification of additional autoantibodies that could p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of HIV-positive People
This is a categorized, alphabetical list of people who are known to have been infected with the human immunodeficiency virus (HIV), the pathogen that causes AIDS, including those who have died. AIDS is a pandemic. Since the beginning of the epidemic, 84.2 million 4.0–113.0 millionpeople have been infected with the HIV virus and about 40.1 million 3.6–48.6 millionpeople have died of HIV. Globally, 38.4 million 3.9–43.8 millionpeople were living with HIV at the end of 2021. An estimated 0.7% .6-0.8%of adults aged 15–49 years worldwide are living with HIV, although the burden of the epidemic continues to vary considerably between countries and regions. The WHO African Region remains most severely affected, with nearly 1 in every 25 adults (3.4%) living with HIV and accounting for more than two-thirds of the people living with HIV worldwide. HIV is spread primarily by unprotected sex (including vaginal, anal, and oral sex), contaminated blood transfusions, hypod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tom Hanks
Thomas Jeffrey Hanks (born July 9, 1956) is an American actor and filmmaker. Known for both his comedic and dramatic roles, he is one of the most popular and recognizable film stars worldwide, and is regarded as an American cultural icon. Hanks is ranked as the fourth-highest-grossing American film actor. His List of awards and nominations received by Tom Hanks, numerous awards include two Academy Awards, seven Primetime Emmy Awards, Emmy Awards, and four Golden Globe Awards; he has also been nominated for five BAFTA Awards and a Tony Award. He received the AFI Life Achievement Award in 2002, the Kennedy Center Honors, Kennedy Center Honor in 2014, the Presidential Medal of Freedom in 2016, and the Golden Globe Cecil B. DeMille Award in 2020. Hanks rose to fame with leading roles in comedies: ''Splash (film), Splash'' (1984), ''The Money Pit'' (1986), ''Big (film), Big'' (1988), and ''A League of Their Own'' (1992). He won two consecutive Academy Awards for Academy Award for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia (film)
''Philadelphia'' is a 1993 American legal drama film directed and produced by Jonathan Demme, written by Ron Nyswaner, and starring Tom Hanks and Denzel Washington. Filmed on location in its namesake city, it tells the story of attorney Andrew Beckett (Hanks) who comes to ask a personal injury attorney, Joe Miller (Washington), to help him sue his former law firm, who fired him after discovering he was gay and that he had AIDS. The cast also features Jason Robards, Mary Steenburgen, Antonio Banderas, and Joanne Woodward. ''Philadelphia'' is one of the first mainstream Hollywood films not only to explicitly address HIV/AIDS and homophobia, but also to portray gay people in a positive light. It premiered in Los Angeles on December 14, 1993 in a benefit for the AIDS Project, and opened in limited release on December 22, before expanding into wide release on January 14, 1994. It grossed $206.7 million worldwide, becoming the 9th highest-grossing film of 1993. The film w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Washington Post
''The Washington Post'', locally known as ''The'' ''Post'' and, informally, ''WaPo'' or ''WP'', is an American daily newspaper published in Washington, D.C., the national capital. It is the most widely circulated newspaper in the Washington metropolitan area and has a national audience. As of 2023, the ''Post'' had 130,000 print subscribers and 2.5 million digital subscribers, both of which were the List of newspapers in the United States, third-largest among U.S. newspapers after ''The New York Times'' and ''The Wall Street Journal''. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. In 1933, financier Eugene Meyer (financier), Eugene Meyer purchased it out of bankruptcy and revived its health and reputation; this work was continued by his successors Katharine Graham, Katharine and Phil Graham, Meyer's daughter and son-in-law, respectively, who bought out several rival publications. The ''Post ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Long-term Nonprogressor
Long-term nonprogressors (LTNPs), are individuals infected with HIV, who maintain a CD4 count greater than 500 without antiretroviral therapy with a detectable viral load. Many of these patients have been HIV positive for 30 years without progressing to the point of needing to take medication in order not to develop AIDS. They have been the subject of a great deal of research, since an understanding of their ability to control HIV infection may lead to the development of immune therapies or a therapeutic vaccine. The classification "Long-term non-progressor" is not permanent, because some patients in this category have gone on to develop AIDS. Long-term nonprogressors typically have viral loads under 10,000 copies /mL blood, do not take antiretrovirals, and have CD4+ counts within the normal range. Most people with HIV not on medication have viral loads which are much higher. It is estimated that around 1 in 500 people with HIV are long-term nonprogressors. Without the symptom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retrovirus
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. After invading a host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus ''retro'' (backward). The new DNA is then retroviral integration, incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along with the cell's own genes, producing the proteins required to assemble new copies of the virus. Many retroviruses cause serious diseases in humans, other mammals, and birds. Retroviruses have many subfamilies in three basic groups. * Oncovirus, Oncoretroviruses (cancer-causing retroviruses) include human T-lymphotropic virus (HTLV) causing a type of leuk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
