No Free Lunch (organization)
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No Free Lunch (organization)
No Free Lunch was a US-based advocacy organization holding that marketing methods employed by drug companies influence the way doctors and other healthcare providers prescribe medications.Tayal U (2004-05-15)''No free lunch'' ''BMJ Careers''. Retrieved on 2007-10-06. The group did outreach to convince physicians to refuse to accept gifts, money, or hospitality from pharmaceutical companies because it claims that these gifts create a conflict of interest for providers. The group also advocated for less involvement of drug companies in medical education and practice in a variety of other ways. History The organization was founded in 2000 by Bob Goodman,O'Reilly KB (2006-01-16)Buy your own lunch: No chance of reciprocity: One doctor's crusade against gifts from the drug industry has grown into a small, but vocal, group ''American Medical News''. American Medical Association. Retrieved on 2007-10-06. an internist from New York City.Ewing A (2005-04-18)ACP and No Free Lunch: Setting t ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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Healthy Skepticism
Healthy Skepticism Inc is an international non-profit organisation whose main aim is to "improve health by reducing harm from misleading drug promotion". Healthy Skepticism was founded in 1983 with the name Medical Lobby for Appropriate Marketing (MaLAM). It was begun by an Australian medical student, Peter R. Mansfield, who had the idea for the organisation during his final year elective in Bangladesh in 1982. MaLAM initially focused on campaigning against questionable marketing practices in developing countries. These included the promotion of appetite stimulants, tonics and anabolic steroids to parents of malnourished children. MaLAM was modelled on Amnesty International and wrote open letters to the international headquarters of pharmaceutical companies questioning them about specific advertisements. MaLAM letters were signed by supporters around the world and contributed to many improvements in drug marketing, several products being removed from the market and many adv ...
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Pharmaceuticals Policy
Pharmaceutical policy is a branch of health policy that deals with the development, provision and use of medications within a health care system. It embraces drugs (both brand name and generic), biologics (products derived from living sources, as opposed to chemical compositions), vaccines and natural health products. Funding of research in the life sciences In many countries, an agency of the national government (in the U.S. the NIH, in the U.K. the MRC, and in India the DST) funds university researchers to study the causes of disease, which in some cases leads to the development of discoveries which can be transferred to pharmaceutical companies and biotechnology companies as a basis for drug development. By setting its budget, its research priorities and making decisions about which researchers to fund, there can be a significant impact on the rate of new drug development and on the disease areas in which new drugs are developed. For example, a major investment by the NIH int ...
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There Ain't No Such Thing As A Free Lunch
"There ain't no such thing as a free lunch" (alternatively, "There is no such thing as a free lunch" or other variants) is a popular adage communicating the idea that it is impossible to get something for nothing. The acronyms TANSTAAFL, TINSTAAFL, and TNSTAAFL are also used. The phrase was in use by the 1930s, but its first appearance is unknown. The "free lunch" in the saying refers to the formerly common practice in American bars of offering a "free lunch" in order to entice drinking customers. The phrase and the acronym are central to Robert A. Heinlein's 1966 science-fiction novel ''The Moon Is a Harsh Mistress'', which helped popularize it. The free-market economist Milton Friedman also increased its exposure and useSafire, William, ''The New York Times'', 2-14-199"On Language; Words Left Out in the Cold" /ref> by paraphrasing it as the title of a 1975 book,Friedman, Milton, ''There's No Such Thing as a Free Lunch'', Open Court Publishing Company, 1975. . and it is used in ...
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Robert Heinlein
Robert Anson Heinlein (; July 7, 1907 – May 8, 1988) was an American science fiction author, aeronautical engineer, and naval officer. Sometimes called the "dean of science fiction writers", he was among the first to emphasize scientific accuracy in his fiction, and was thus a pioneer of the subgenre of hard science fiction. His published works, both fiction and non-fiction, express admiration for competence and emphasize the value of critical thinking. His plots often posed provocative situations which challenged conventional social mores. His work continues to have an influence on the science-fiction genre, and on modern culture more generally. Heinlein became one of the first American science-fiction writers to break into mainstream magazines such as ''The Saturday Evening Post'' in the late 1940s. He was one of the best-selling science-fiction novelists for many decades, and he, Isaac Asimov, and Arthur C. Clarke are often considered the "Big Three" of English-language sci ...
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No Free Lunch Theorem
In mathematical folklore, the "no free lunch" (NFL) theorem (sometimes pluralized) of David Wolpert and William Macready appears in the 1997 "No Free Lunch Theorems for Optimization".Wolpert, D.H., Macready, W.G. (1997),No Free Lunch Theorems for Optimization, ''IEEE Transactions on Evolutionary Computation'' 1, 67. Wolpert had previously derived no free lunch theorems for machine learning (statistical inference).Wolpert, David (1996),The Lack of ''A Priori'' Distinctions between Learning Algorithms, ''Neural Computation'', pp. 1341–1390. The name alludes to the saying "there ain't no such thing as a free lunch", that is, there are no easy shortcuts to success. In 2005, Wolpert and Macready themselves indicated that the first theorem in their paper "state that any two optimization algorithms are equivalent when their performance is averaged across all possible problems".Wolpert, D.H., and Macready, W.G. (2005) "Coevolutionary free lunches", ''IEEE Transactions on Evolutionary ...
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Milton Friedman
Milton Friedman (; July 31, 1912 – November 16, 2006) was an American economist and statistician who received the 1976 Nobel Memorial Prize in Economic Sciences for his research on consumption analysis, monetary history and theory and the complexity of stabilization policy. With George Stigler and others, Friedman was among the intellectual leaders of the Chicago school of economics, a neoclassical school of economic thought associated with the work of the faculty at the University of Chicago that rejected Keynesianism in favor of monetarism until the mid-1970s, when it turned to new classical macroeconomics heavily based on the concept of rational expectations. Several students, young professors and academics who were recruited or mentored by Friedman at Chicago went on to become leading economists, including Gary Becker, Robert Fogel, Thomas Sowell and Robert Lucas Jr. Friedman's challenges to what he called "naive Keynesian theory" began with his interpretation ...
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Inverse Benefit Law
The inverse benefit law states that the ratio of benefits to harms among patients taking new drugs tends to vary inversely with how extensively a drug is marketed. Two Americans, Howard Brody and Donald Light, have defined the inverse benefit law, inspired by Tudor Hart's inverse care law. A drug effective for a serious disorder is less and less effective as it is promoted for milder cases and for other conditions for which the drug was not approved. Although effectiveness becomes more diluted, the risks of harmful side effects persist, and thus the benefit-harm ratio worsens as a drug is marketed more widely. The inverse benefit law highlights the need for comparative effectiveness research and other reforms to improve evidence-based prescribing. State of affairs The law is manifested through 6 basic marketing strategies: * reducing thresholds for diagnosing disease, * relying on surrogate endpoints, * exaggerating safety Safety is the state of being "safe", the cond ...
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Pharmaceutical Research And Manufacturers Of America
Pharmaceutical Research and Manufacturers of America (PhRMA, pronounced ), formerly known as the Pharmaceutical Manufacturers Association, is a trade group representing companies in the pharmaceutical industry in the United States. Founded in 1958, PhRMA lobbies on behalf of pharmaceutical companies. PhRMA is headquartered in Washington, DC. The organization has lobbied fiercely against allowing Medicare to negotiate drug prices for Medicare recipients. At the state level, the organization has lobbied to prevent price limits and greater price transparency for drugs. PhRMA has given substantial dark money donations to right-wing advocacy groups such as the American Action Network (which lobbied heavily against the Affordable Care Act), the Koch brothers' Americans for Prosperity and Grover Norquist's Americans for Tax Reform, while rarely providing some donations to centrist or moderately right-leaning groups such as Center Forward. Membership Leadership George A. Scangos, ...
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Ray Moynihan
Ray Moynihan is an Australian researcher, health journalist, documentary-maker and author. Employed for many years as an investigative journalist at the Australian Broadcasting Corporation, he has also worked for the Australian Financial Review and is currently a visiting editor at the British Medical Journal and a conjoint lecturer at the University of Newcastle. He was also a correspondent for Radio New Zealand. His stories regularly appear in the BMJ, The Australian, Crikey and the ABC.in Australia. Moynihan is a prolific public speaker. Early life and Career Ray Moynihan grew up in Brisbane, Queensland and on graduating from the University of Queensland, worked as a reporter at community radio station 4ZZZ. He joined ABC Radio News Brisbane in the mid 1980s as a reporter, staying with the organisation for over a decade in a variety of roles including the presenter of investigative radio program 'Background Briefing,' reporter for JJJ and the '7.30 Report' and as researc ...
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Pharmaceutical Marketing
Many countries have measures in place to limit advertising by pharmaceutical companies. Pharmaceutical company spending on marketing generally exceeds that of its research budget. In Canada, $1.7 billion was spent in 2004 to market drugs to physicians; in the United States, $21 billion was spent in 2002. In 2005, money spent on pharmaceutical marketing in the United States was estimated at $29.9 billion with one estimate as high as $57 billion. When the U.S. numbers are broken down, 56% was free samples, 25% was pharmaceutical sales representative "detailing" (promoting drugs directly to) physicians, 12.5% was direct to user advertising, 4% on detailing to hospitals, and 2% on journal ads. There is some evidence that marketing practices can negatively affect both patients and the health care profession. To health care providers Marketing to health-care providers takes three main forms: activity by pharmaceutical sales representatives, provision of drug samples, and sponsoring ...
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