Nikola P. Pavletich
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Nikola P. Pavletich
Nikola Panayot Pavletich is the former chair of structural biology at Memorial Sloan Kettering Cancer Center. Education Pavletich received his BS in chemistry from Caltech in 1988 and his PhD in molecular biology and genetics from Johns Hopkins University School of Medicine in 1991. He did a postdoc at MIT with Carl Pabo. Career He joined the faculty at Sloan Kettering in 1993 and was named chair of the Structural Biology Program in 2003. He has been an HHMI investigator since 1997. His laboratory researches malignant cell growth and DNA damage contributing to the development of cancer. DNA damage repair is a significant factor in whether a cell will become cancerous after genetic insult. Some of his major focuses have been the mTOR pathway and BRCA1. His lab uses x-ray crystallography to determine how proteins interact. Awards * 1994 – Pew Scholar * 1995 – Beckman Young Investigators Award * 1999 – MIT Innovators under 35 * 2000 – AACR Award for Outstanding Achieveme ...
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Structural Biology
Structural biology is a field that is many centuries old which, and as defined by the Journal of Structural Biology, deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every level of organization. Early structural biologists throughout the 19th and early 20th centuries were primarily only able to study structures to the limit of the naked eye's visual acuity and through magnifying glasses and light microscopes. In the 20th century, a variety of experimental techniques were developed to examine the 3D structures of biological molecules. The most prominent techniques are X-ray crystallography, nuclear magnetic resonance, and electron microscopy. Through the discovery of X-rays and its applications to protein crystals, structural biology was revolutionized, as now scientists could obtain the three-dimensional structures of biological molecules in atomic detail. Likewise, NMR spectroscopy allowed information about p ...
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Paul Marks Prize For Cancer Research
The Paul Marks Prize for Cancer Research is awarded by the Memorial Sloan Kettering Cancer Center to recognize cancer researchers who are making significant contributions to the understanding of cancer or are improving the treatment of the disease through basic or clinical research. The prize is awarded biennially to up to three recipients aged 45 or younger, who are selected by a panel of investigators from leading research institutions. Each presents his or her work at a scientific symposium at Memorial Sloan Kettering Cancer Center, receives a medal and shares a cash award of $150,000. The prize is named after Paul A. Marks, President Emeritus of the Memorial Sloan Kettering Cancer Center. Prizewinners SourceMemorial Sloan Kettering Cancer Center*2021 Ralph J. DeBerardinis, Sun Hur, Charles Swanton *2019 Nathanael Gray, Joshua Mendell, Christopher Vakoc *2017 Gad Getz, Chuan He, Aviv Regev *2015 Bradley Bernstein, Howard Y. Chang, and Daniel Durocher *2013 Simon J. Bou ...
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Members Of The United States National Academy Of Sciences
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * Church membership, belonging to a local Christian congregation, a Christian denomination and the universal Church * Member, a participant in a club or learned society A learned society (; also learned academy, scholarly society, or academic association) is a ...
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Fellows Of The American Academy Of Arts And Sciences
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses *Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: *Grant Fellows Grant Fellows (April 13, 1865 – July 16, 1929) was an American jurist. Born in Hudson Township, Lenawee County, Michigan, Fellows went to Hudson High School in Hudson, Michigan. Fellows studied la ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Cancer Researchers
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of a ce ...
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Institute Of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Sciences (NAS), National Academy of Engineering (NAE), and the National Research Council (NRC). The National Academy of Medicine provides national and international advice on issues relating to health, medicine, health policy, and biomedical science. It aims to provide unbiased, evidence-based, and authoritative information and advice concerning health and science policy to policy-makers, professionals, leaders in every sector of society, and the public at large. Operating outside the framework of the U.S. federal government, it relies on a volunteer workforce of scientists and other experts, operating under a formal peer-review system. As a national academy, the organization a ...
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American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, ''Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commercial s ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve ''pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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AACR Award For Outstanding Achievement In Cancer Research
The American Association for Cancer Research gives several annual awards for significant contributions to the field of cancer research. AACR Award for Lifetime Achievement in Cancer Research This award recognizes prodigious scientists that have made profound contributions to the field of cancer research. * 2018: Joseph R. Bertino * 2017: Mina Bissell * 2016: Robert A. Weinberg * 2015: Mario R. Capecchi * 2014: Douglas Hanahan * 2013: Harold L. Moses * 2012: Beatrice Mintz * 2011: Susan Band Horwitz * 2010: Janet D. Rowley * 2009: Joseph F. Fraumeni, Jr. * 2008: Harald zur Hausen * 2007: Donald Metcalf * 2006: Bernard Fisher * 2005: Alfred G. Knudson, Jr. * 2004: Emil Frei III AACR Award for Outstanding Achievement in Cancer Research This award recognizes the outstanding research of investigators under the age of 40. * This award has not been given since 2016. * 2016: Franziska Michor * 2015: Christopher R. Vakoc * 2014: Nima Sharifi * 2013: Roger S. Lo * 2012: Yibin ...
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