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Nazi Human Experimentation
Nazi human experimentation was a series of medical experiments on large numbers of prisoners, including children, by Nazi Germany in its concentration camps in the early to mid 1940s, during World War II and the Holocaust. Chief target populations included Romani, Sinti, ethnic Poles, Soviet POWs, disabled Germans, and Jews from across Europe. Nazi physicians and their assistants forced prisoners into participating; they did not willingly volunteer and no consent was given for the procedures. Typically, the experiments were conducted without anesthesia and resulted in death, trauma, disfigurement, or permanent disability, and as such are considered examples of medical torture. At Auschwitz and other camps, under the direction of Eduard Wirths, selected inmates were subjected to various experiments that were designed to help German military personnel in combat situations, develop new weapons, aid in the recovery of military personnel who had been injured, and to advan ...
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Auschwitz Concentration Camp
Auschwitz concentration camp ( (); also or ) was a complex of over 40 concentration and extermination camps operated by Nazi Germany in occupied Poland (in a portion annexed into Germany in 1939) during World War II and the Holocaust. It consisted of Auschwitz I, the main camp (''Stammlager'') in Oświęcim; Auschwitz II-Birkenau, a concentration and extermination camp with gas chambers; Auschwitz III-Monowitz, a labor camp for the chemical conglomerate IG Farben; and dozens of subcamps. The camps became a major site of the Nazis' final solution to the Jewish question. After Germany sparked World War II by invading Poland in September 1939, the '' Schutzstaffel'' (SS) converted Auschwitz I, an army barracks, into a prisoner-of-war camp. The initial transport of political detainees to Auschwitz consisted almost solely of Poles for whom the camp was initially established. The bulk of inmates were Polish for the first two years. In May 1940, German criminals broug ...
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Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium lining a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial tissue factor to plasma factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation (clotting) factors beyond factor VII ( listed below) respond in a cascade to form fibrin strands, which strengthen the platelet plug. Disord ...
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Sulfanilamide
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to previous wars. Sulfanilamide is rarely if ever used systemically due to toxicity and because more effective sulfonamides are available for this purpose. Modern antibiotics have supplanted sulfanilamide on the battlefield; however, sulfanilamide remains in use today in the form of topical preparations, primarily for treatment of vaginal yeast infections mainly vulvovaginitis which is caused by '' Candida albicans''. The term "sulfanilamides" is also sometimes used to describe a family of molecules containing these functional groups. Examples include: * Furosemide, a loop diuretic * Sulfadiazine, an antibiotic * Sulfamethoxazole, an antibio ...
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Jaundice
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. The prevalence of jaundice in adults is rare, while jaundice in babies is common, with an estimated 80% affected during their first week of life. The most commonly associated symptoms of jaundice are itchiness, pale feces, and dark urine. Normal levels of bilirubin in blood are below 1.0  mg/ dl (17  μmol/ L), while levels over 2–3 mg/dl (34–51 μmol/L) typically result in jaundice. High blood bilirubin is divided into two types – unconjugated and conjugated bilirubin. Causes of jaundice vary from relatively benign to potentially fatal. High unconjugated bilirubin may be due to excess red blood cell breakdown, large bruises, genetic conditions s ...
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Epidemic
An epidemic (from Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics of infectious diseases are generally caused by several factors including a significant change in the ecology of the areal population (e.g., increased stress maybe additional reason or increase in the density of a vector species), the introduction of an emerging pathogen to an areal population (by movement of pathogen or host) or an unexpected genetic change that is in the pathogen reservoir. Generally, epidemics concerns with the patterns of infectious disease spread. An epidemic may occur when host immunity to either an established pathogen or newly emerging novel pathogen is suddenly reduced below that found in the endemic equilibrium and the transmission threshold is exceeded. For example, in meningococcal infections, an attack rate in excess of ...
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Medical Ethics
Medical ethics is an applied branch of ethics which analyzes the practice of clinical medicine and related scientific research. Medical ethics is based on a set of values that professionals can refer to in the case of any confusion or conflict. These values include the respect for autonomy, non-maleficence, beneficence, and justice. Such tenets may allow doctors, care providers, and families to create a treatment plan and work towards the same common goal. It is important to note that these four values are not ranked in order of importance or relevance and that they all encompass values pertaining to medical ethics. However, a conflict may arise leading to the need for hierarchy in an ethical system, such that some moral elements overrule others with the purpose of applying the best moral judgement to a difficult medical situation. Medical ethics is particularly relevant in decisions regarding involuntary treatment and involuntary commitment. There are several codes of conduct. ...
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Nuremberg Code
The Nuremberg Code (german: Nürnberger Kodex) is a set of ethical research principles for human experimentation created by the court in '' U.S. v Brandt'', one of the Subsequent Nuremberg trials that were held after the Second World War. Though it was articulated as part of the court's verdict in the trial, the Code would later become significant beyond its original context; in a review written on the 50th anniversary of the ''Brandt'' verdict, Jay Katz writes that "a careful reading of the judgment suggests that he authorswrote the Code for the practice of human experimentation whenever it is being conducted." Background The origin of the Code began in pre–World War II German politics, particularly during the 1930s and 1940s. Starting in the mid-1920s, German physicians, usually proponents of racial hygiene, were accused by the public and the medical society of unethical medical practices. The use of racial hygiene was supported by the German government in order to promote ...
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Doctors' Trial
The Doctors' Trial (officially ''United States of America v. Karl Brandt, et al.'') was the first of 12 trials for war crimes of high-ranking German officials and industrialists that the United States authorities held in their occupation zone in Nuremberg, Germany, after the end of World War II. These trials were held before US military courts, not before the International Military Tribunal, but took place in the same rooms at the Palace of Justice. The trials are collectively known as the " subsequent Nuremberg trials", formally the "Trials of War Criminals before the Nuremberg Military Tribunals" (NMT). Twenty of the twenty-three defendants were medical doctors and were accused of having been involved in Nazi human experimentation and mass murder under the guise of euthanasia. The indictment was filed on 25 October 1946; the trial lasted from 9 December that year until 20 August 1947. Of the 23 defendants, seven were acquitted and seven received death sentences; the remain ...
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Mauthausen-Gusen Concentration Camp
Mauthausen was a Nazi concentration camp on a hill above the market town of Mauthausen (roughly east of Linz), Upper Austria. It was the main camp of a group with nearly 100 further subcamps located throughout Austria and southern Germany. The three Gusen concentration camps in and around the village of St Georgen/Gusen, just a few kilometres from Mauthausen, held a significant proportion of prisoners within the camp complex, at times exceeding the number of prisoners at the Mauthausen main camp. The Mauthausen main camp operated from 8 August 1938, several months after the German annexation of Austria, to 5 May 1945, when it was liberated by the United States Army. Starting with the camp at Mauthausen, the number of subcamps expanded over time. In January 1945, the camps contained roughly 85,000 inmates. As at other Nazi concentration camps, the inmates at Mauthausen and its subcamps were forced to work as slave labour, under conditions that caused many deaths. Mautha ...
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Aribert Heim
Aribert Ferdinand Heim (28 June 191410 August 1992), also known as Dr. Death and Butcher of Mauthausen, was an Austrian ''Schutzstaffel'' (SS) doctor. During World War II, he served at the Mauthausen-Gusen concentration camp in Mauthausen, killing and torturing inmates using various methods, such as the direct injection of toxic compounds into the hearts of his victims. After the war, Heim lived in Cairo, Egypt, under the alias of Tarek Farid Hussein after his conversion to Islam. In February 2009, after years of attempts to locate him, German television network ZDF had found Heim's passport and other documents in Cairo. It was then reported that Heim had died there on 10 August 1992 from complications of rectal cancer, according to testimony by his son Ruediger and lawyer. This information, though set forth by a German court, was questioned by Efraim Zuroff, a leading Nazi hunter of the Simon Wiesenthal Center.
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Josef Mengele
, allegiance = , branch = Schutzstaffel , serviceyears = 1938–1945 , rank = '' SS''-'' Hauptsturmführer'' (Captain) , servicenumber = , battles = , unit = , awards = , commands = , spouse = , children = Rolf Mengele , alma_mater = Josef Rudolf Mengele (; 16 March 19117 February 1979), also known as the Angel of Death (german: Todesengel), was a German (SS) officer and physician during World War II. He is mainly remembered for his actions at the Auschwitz II (Birkenau) concentration camp, where he performed deadly experiments on prisoners, was a member of the team of doctors who selected victims to be killed in the gas chambers, and was one of the doctors who administered the gas. With Red Army troops sweeping through German-occupied Poland, Mengele was transferred from Auschwitz to the Gross-Rosen concentration camp on 17 January 1945, ten days before the arrival of the Soviet forces at ...
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