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Noreen Murray
Noreen Elizabeth, Lady Murray (; 26 February 1935 – 12 May 2011) was an English molecular geneticist who helped pioneer recombinant DNA technology (genetic engineering) by creating a series of bacteriophage lambda vectors into which genes could be inserted and expressed in order to examine their function. During her career she was recognised internationally as a pioneer and one of Britain's most distinguished and highly respected molecular geneticists. Until her 2001 retirement she held a personal chair in molecular genetics at the University of Edinburgh.. She was president of the Genetical Society, vice president of the Royal Society, and a member of the UK Science and Technology Honours Committee. Education Noreen Parker was brought up in the village of Read, Lancashire, then from the age of five in Bolton-le-Sands. She was educated at Lancaster Girls' Grammar School, at King's College London ( BSc), and received her PhD from the University of Birmingham in 1959 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lancashire
Lancashire ( , ; abbreviated Lancs) is the name of a Historic counties of England, historic county, Ceremonial County, ceremonial county, and non-metropolitan county in North West England. The boundaries of these three areas differ significantly. The non-metropolitan county of Lancashire was created by the Local Government Act 1972. It is administered by Lancashire County Council, based in Preston, Lancashire, Preston, and twelve district councils. Although Lancaster, Lancashire, Lancaster is still considered the county town, Preston is the administrative centre of the non-metropolitan county. The ceremonial county has the same boundaries except that it also includes Blackpool and Blackburn with Darwen, which are unitary authorities. The historic county of Lancashire is larger and includes the cities of Manchester and Liverpool as well as the Furness and Cartmel peninsulas, but excludes Bowland area of the West Riding of Yorkshire transferred to the non-metropolitan county ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vector (molecular Biology)
In molecular cloning, a vector is any particle (e.g., plasmids, cosmids, Lambda phages) used as a vehicle to artificially carry a foreign nucleic sequence – usually DNA – into another cell, where it can be replicated and/or expressed. A vector containing foreign DNA is termed recombinant DNA. The four major types of vectors are plasmids, viral vectors, cosmids, and artificial chromosomes. Of these, the most commonly used vectors are plasmids. Common to all engineered vectors have an origin of replication, a multicloning site, and a selectable marker. The vector itself generally carries a DNA sequence that consists of an insert (in this case the transgene) and a larger sequence that serves as the "backbone" of the vector. The purpose of a vector which transfers genetic information to another cell is typically to isolate, multiply, or express the insert in the target cell. All vectors may be used for cloning and are therefore cloning vectors, but there are also vect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Motor Neurone Disease
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most common type of motor neuron diseases. Early symptoms of ALS include stiff muscles, muscle twitches, and gradual increasing weakness and muscle wasting. ''Limb-onset ALS'' begins with weakness in the arms or legs, while ''bulbar-onset ALS'' begins with difficulty speaking or swallowing. Half of the people with ALS develop at least mild difficulties with thinking and behavior, and about 15% develop frontotemporal dementia. Most people experience pain. The affected muscles are responsible for chewing food, speaking, and walking. Motor neuron loss continues until the ability to eat, speak, move, and finally the ability to breathe is lost. ALS eventually causes paralysis and early death, usually from respiratory failure. Most cases of ALS (a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
King's Buildings
The King's Buildings (colloquially known as just King's or KB) is a campus of the University of Edinburgh in Scotland. Located in the suburb of Blackford, the site contains most of the schools within the College of Science and Engineering, excepting only the School of Informatics and part of the School of Geosciences, which are located at the central George Square campus. The campus lies south of West Mains Road, west of Mayfield Road and east of Blackford Hill, about south of George Square. Scotland's Rural College (SRUC) and Biomathematics and Statistics Scotland (BioSS) also have facilities there. History In 1919 Edinburgh University bought the land of West Mains Farm in the south of the city with the intention of building a satellite campus specialising in the Sciences. The first building was the Chemistry Building (renamed the Joseph Black Building) designed by Arthur Forman Balfour Paul in 1919. Building started in 1920 and was completed after 1924 by John Fraser M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatitis B
Hepatitis B is an infectious disease caused by the '' Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. For others, symptoms may appear 30 to 180 days after becoming infected and can include a rapid onset of sickness with nausea, vomiting, yellowish skin, fatigue, dark urine, and abdominal pain. Symptoms during acute infection typically last for a few weeks, though some people may feel sick for up to six months. Deaths resulting from acute stage HBV infections are rare. An HBV infection lasting longer than six months is usually considered chronic. The likelihood of developing chronic hepatitis B is higher for those who are infected with HBV at a younger age. About 90% of those infected during or shortly after birth develop chronic hepatitis B, while less than 10% of those infected after the age of five develop chronic cases. Most of those ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylactic (to pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Times Higher Education
''Times Higher Education'' (''THE''), formerly ''The Times Higher Education Supplement'' (''The Thes''), is a British magazine reporting specifically on news and issues related to higher education. Ownership TPG Capital acquired TSL Education from Charterhouse in a £400 million deal in July 2013 and rebranded TSL Education, of which Times Higher Education was a part, as TES Global. The acquisition by TPG marked the third change of ownership in less than a decade for Times Higher Education, which was previously owned by News International before being acquired by Exponent Private Equity in 2005. In March 2019, private equity group Inflexion Pvt. Equity Partners LLP acquired Times Higher Education from TPG Capital, becoming THE's fourth owners in 15 years. Following the acquisition by the private equity group, Times Higher Education was carved out as an independent entity from TES Global. The investment was made by Inflexion's dedicated mid-market buyout funds. The exclusive a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kenneth Murray (molecular Biologist)
Sir Kenneth "Ken" Murray FRS FRSE FRCPath (30 December 1930 – 7 April 2013) was a British molecular biologist and the Biogen Professor of Molecular Biology at the University of Edinburgh. An important early figure in genetic engineering, Murray cofounded Biogen. There, he and his team developed one of the first vaccines against hepatitis B. Along with his wife, biologist Lady Noreen (née Parker), Murray also founded the Darwin Trust of Edinburgh, a charity supporting young biologists in their doctoral studies. The Telegraph, 14 April 2013 Education and career Murray achieved a 1st class honours degree in chemistry followed by PhD from the |
Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title '' Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at universities or work in academic, e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lancaster Girls' Grammar School
Lancaster Girls' Grammar School (LGGS) is a selective state grammar school with academy status for girls on ''Regent Street'' in Lancaster, England. It was established in 1907. About LGGS LGGS gained Technology College status in 1995, and Language College status in 2007. Centenary The school passed its centenary year in 2007 bringing a few changes along with it. The school logo was updated and the uniform changed along with a new hall added to the main part of the school building. House system Lancaster Girls' Grammar school has a House system as girls are sorted into these house in first year, and remain affiliated with them for the rest of their school career. The Houses are named after the twin towns of Lancaster: * Aalborg represented by the colour blue * Perpignan represented by the colour green * Rendsburg represented by the colour red * Lublin represented by the colour yellow There are inter-house competitions throughout the year, including the Performing Arts Festi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bolton-le-Sands
Bolton-le-Sands is a large village and civil parish of the City of Lancaster in Lancashire, England. The parish had a population of 4,098 recorded in the 2001 census, increasing to 4,127 at the 2011 Census. Referred to as ''Bodeltone'' in the Domesday book, the village was known as Bolton until the arrival of the railways, when the name was changed to Bolton-le-Sands to differentiate from similarly named towns on the same line, such as Bolton which was then a part of Lancashire and called Bolton-le-Moors. The oldest church in the village, founded prior to 1094, is the Church of England Holy Trinity church, originally dedicated to St Michael. The oldest part of the current building is the tower, supposed to have been built around 1500. The nave and chancel date from the 19th century. The other churches are the Roman Catholic St Mary of the Angels and the Christ Church United Reformed Church. The Lancaster Canal, built in the 1790s, is a major feature of the village. Also passi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Read, Lancashire
Read is a village in Lancashire 5 miles west northwest of Burnley and 2 miles east of Whalley. It is on the A671 which is the main road between Burnley and Clitheroe. The population of the civil parish as taken at the 2011 census was 1,419. History The name "Read" is a contraction of Old English words meaning female roe deer and ridge or headland. The old village developed in the 16th century along the main mediaeval road between Whalley and Padiham. The Battle of Read Old Bridge was fought in 1643 between the Royalist and Parliamentarian forces. The Royalist force of about 4,000 men, commanded by the Earl of Derby, had taken the village of Whalley. The Parliamentary force, numbering only about 400 men, were positioned near Read Old Bridge. As the Royalist forces approached the bridge they faced withering musket fire causing them to retreat in confusion. The Royalists gave up Whalley; about 400 largely untrained soldiers had beaten 4,000, winning Lancashire for Parliamen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
