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Nonivamide
Nonivamide, also called pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin. Nonivamide is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the confectionery industry to create a hot sensation, and in the pharmaceutical industry in some formulations as a cheaper alternative to capsaicin. Like capsaicin, it can deter mammals (but not birds or insects) from consuming plants or seeds (e.g. squirrels and bird feeder seeds).http://www.aversiontech.com/hot-and-spicy/nonivamide-pava/Retrieved 16 July 2010 This is consistent with nonivamide's role as a TRPV1 ion channel agonist. Mammalian TRPV1 is activated by heat and capsaicin, but the avian form is insensitive to capsaicin. Nonivamide is used (under the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsaicinoids
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) (, rarely ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a potent irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related amides (capsaicinoids) are produced as secondary metabolites by chili peppers, likely as deterrents against certain mammals and fungi. Pure capsaicin is a hydrophobic, colorless, highly pungent (i.e., spicy) crystalline solid. Natural function Capsaicin is present in large quantities in the placental tissue (which holds the seeds), the internal membranes and, to a lesser extent, the other fleshy parts of the fruits of plants in the genus ''Capsicum''. The seeds themselves do not produce any capsaicin, although the highest concentration of capsaicin can be found in the white pith of the inner wall, where the seeds are attached. The seeds of ''Capsicum'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsaicin
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) (, rarely ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a potent Irritation, irritant for Mammal, mammals, including humans, and produces a sensation of burning in any Tissue (biology), tissue with which it comes into contact. Capsaicin and several related amides (capsaicinoids) are produced as secondary metabolites by chili peppers, likely as deterrents against certain mammals and fungi. Pure capsaicin is a hydrophobic, colorless, highly pungent (i.e., spicy) crystalline solid. Natural function Capsaicin is present in large quantities in the Placentation#In plants, placental tissue (which holds the seeds), the internal membranes and, to a lesser extent, the other fleshy parts of the fruits of plants in the genus ''Capsicum''. The seeds themselves do not produce any capsaicin, although the highest concentration of capsaicin can be found in the white Fruit anatomy#Mesocar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PAVA Spray
PAVA spray is an tear gas, incapacitant spray similar to pepper spray. It is dispensed from a handheld canister, in a liquid stream. It contains a 0.3% solution of nonivamide, pelargonic acid vanillylamide (PAVA), also called nonivamide, a synthetic capsaicinoid (analogue of capsaicin), in a solvent of aqueous ethanol. The propellant is nitrogen. This solution has been selected because this is the minimum concentration which will fulfill the purpose of the equipment: namely, to minimise a person's capacity for resistance, without unnecessarily prolonging their discomfort. PAVA is significantly more potent than CS gas. The liquid stream is a spray pattern and has a maximum effective range of up to . Maximum accuracy, however, will be achieved over a distance of . The operating distance is the distance between the canister and the subject's eyes, not the distance between the user and the subject. Effects PAVA primarily affects the eyes, causing closure and severe pain. The pain to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control
Riot control is a form of public order policing used by law enforcement, military, paramilitary or security forces to social control, control, disperse, and arrest people who are involved in a riot, unlawful Demonstration (people), demonstration or unlawful protest. If a riot is spontaneous, then actions which cause people to stop and think (e.g. loud noises or issuing instructions in a calm tone) can be enough to stop it. However, these methods usually fail when there is severe anger, or the riot was planned or organized. Riot control personnel have long used less lethal weapons such as Baton (law enforcement), batons and whips to disperse crowds and detain rioters. Since the 1980s, riot control officers have also used tear gas, pepper spray, rubber bullets, stun grenades, and electric tasers. In some cases, riot squads may also use Long Range Acoustic Devices, water cannons, armoured fighting vehicles, aerial surveillance, police dogs or mounted police on horses. Persons perform ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pepper Spray
Pepper spray, oleoresin capsicum spray, OC spray, capsaicin spray, mace, or capsicum spray is a Tear gas, lachrymator (tear gas) product containing as its active ingredient the chemical compound capsaicin, which irritates the eyes with burning and pain sensations and so causes them to close, bringing temporary blindness. This blindness allows officers to more easily restrain subjects and permits people in danger to use pepper spray in self-defense for an opportunity to escape. It also causes temporary discomfort and burning of the lungs which causes shortness of breath. Pepper spray is used as a less lethal weapon in Police, policing, riot control, crowd control, and self-defense, including defense against dogs and bears. Pepper spray was engineered originally for defense against bears, cougars, wolves and other dangerous predators, and is often referred to colloquially as bear spray. Kamran Loghman, who developed it for use in riot control, wrote the guide for police departm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FN 303
The FN 303 is a semi-automatic less-lethal riot gun designed and manufactured by Fabrique Nationale de Herstal. The FN 303 uses compressed air to fire projectiles from a 15-round drum magazine. It is designed to incapacitate the target through blunt trauma without causing critical injuries, and is most widely used for riot control and other kinds of combat where lethal weapons should be avoided. The 303 can be fired from the shoulder using adjustable iron sights, or it can be mounted in an under-barrel configuration on most assault rifles when its stock assembly is removed (in this configuration, it is designated ''M303''). It also comes with a top-mounted Picatinny rail that can fit most commercial weapon accessories, such as telescopic sights, laser sights and tactical lights. FN markets its own set of accessories for the launcher, including tactical vests, slings, carrying bags, and gas compressors. It is accurate at distances up to . FN also produce a pistol variant, the FN ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lachrymatory Agents , a small vessel of terracotta or glass found in Roman and late Greek tombs, thought to have been used to collect the tears of mourners at funerals
{{disambiguation ...
Lachrymatory or lacrymatory may refer to: * Something that has the effect of ''lachrymation'', causing the secretion of tears * Tear gas, known formally as a ''lachrymatory agent'' or ''lachrymator'' * A lacrymatory A lacrymatory, lachrymatory or lacrimarium (from the Latin ''lacrima'', ' tear') is a small vessel of terracotta or, more frequently, of glass, found in Roman and late Greek tombs, and formerly supposed to have been bottles into which mourners ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control Agents
A riot or mob violence is a form of civil disorder commonly characterized by a group lashing out in a violent public disturbance against authority, property, or people. Riots typically involve destruction of property, public or private. The property targeted varies depending on the riot and the inclinations of those involved. Targets can include shops, cars, restaurants, state-owned institutions, and religious buildings. Riots often occur in reaction to a grievance or out of dissent. Historically, riots have occurred due to poverty, unemployment, poor living conditions, governmental oppression, taxation or conscription, conflicts between ethnic groups (race riot) or religions (e.g., sectarian violence, pogrom), the outcome of a sporting event (e.g., sports riot, football hooliganism) or frustration with legal channels through which to air grievances. While individuals may attempt to lead or control a riot, riots typically consist of disorganized groups that are freque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylacetylrinvanil
Phenylacetylrinvanil (IDN-5890) is a synthetic analogue of capsaicin which acts as a potent and selective agonist for the TRPV1 receptor, with slightly lower potency than resiniferatoxin, though still around 300 times the potency of capsaicin. It is an amide of vanillylamine and ricinoleic acid Ricinoleic acid, formally called 12-hydroxy-9-''cis''-octadecenoic acid, is a fatty acid. It is an Unsaturated fatty acid, unsaturated omega-9 fatty acid and a hydroxy acid. It is a major component of the seed oil obtained from the seeds of casto ..., with the hydroxyl group on ricinoleic acid esterified with phenylacetic acid. It is used to study the function of the TRPV1 receptor and its downstream actions, and has also shown anti-cancer effects ''in vitro''. References Capsaicinoids Transient receptor potential channel modulators {{pharm-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lidocaine
Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia and ventricular fibrillation. When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area. It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding. If injected intravenously, it may cause cerebral effects such as confusion, changes in vision, numbness, tingling, and vomiting. It can cause low blood pressure and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage. It appears to be generally safe for use in pregnancy. A lower dose may be required in those with liver problems. I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blepharospasm
Blepharospasm is a neurological disorder characterized by intermittent, involuntary spasms and contractions of the orbicularis oculi muscle, orbicularis oculi (eyelid) muscles around both eyes. These result in abnormal twitching or blinking, and in the extreme, sustained eyelid closure resulting in functional blindness. The word blepharospasm is derived from the Greek: βλέφαρον / blepharon, eyelid, and σπασμός / spasmos, ''spasm,'' an uncontrolled muscle contraction. The condition should be distinguished from the more common, and milder, involuntary quivering of an eyelid, known as myokymia or fasciculation. Blepharospasm is one form of a group of movement disorders called dystonia. It may be a primary or secondary disorder. The primary disorder is benign essential blepharospasm, in which term the qualifier ''essential'' indicates that the Idiopathic, cause is unknown. Blepharospasm may occur as secondary to conditions including dry eyes and other specific ocul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
