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Neurooncology
Neuro-oncology is the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life-threatening ( astrocytoma, glioma, glioblastoma multiforme, ependymoma, pontine glioma, and brain stem tumors are among the many examples of these). Among the malignant brain cancers, gliomas of the brainstem and pons, glioblastoma multiforme, and high-grade (highly anaplastic) astrocytoma/oligodendroglioma are among the worst. In these cases, untreated survival usually amounts to only a few months, and survival with current radiation and chemotherapy treatments may extend that time from around a year to a year and a half, possibly two or more, depending on the patient's condition, immune function, treatments used, and the specific type of malignant brain neoplasm. Surgery may in some cases be curative, but, as a general rule, malignant brain cancers tend to regenerate and emerge from remission easily, especially highly malignant cases. In such case ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Tumor
A brain tumor (sometimes referred to as brain cancer) occurs when a group of cells within the Human brain, brain turn cancerous and grow out of control, creating a mass. There are two main types of tumors: malignant (cancerous) tumors and benign tumor, benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and metastasis, secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved. Where symptoms exist, they may include headaches, seizures, problems with visual perception, vision, vomiting and cognition, mental changes. Other symptoms may include difficulty walking, speaking, with sensations, or unconsciousness. The cause of most brain tumors is unknown, though up to 4% of brain cancers may be caused by CT scan radiation. Uncommo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glioblastoma Multiforme
Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. Initial signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke. Symptoms often worsen rapidly and may progress to unconsciousness. The cause of most cases of glioblastoma is not known. Uncommon risk factors include genetic disorders, such as neurofibromatosis and Li–Fraumeni syndrome, and previous radiation therapy. Glioblastomas represent 15% of all brain tumors. They are thought to arise from astrocytes. The diagnosis typically is made by a combination of a CT scan, MRI scan, and tissue biopsy. There is no known method of preventing the cancer. Treatment usually involves surgery, after which chemotherapy and radiation therapy are used. The medication temozolomide is frequently used as pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Neoplasms
A brain tumor (sometimes referred to as brain cancer) occurs when a group of cells within the brain turn cancerous and grow out of control, creating a mass. There are two main types of tumors: malignant (cancerous) tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved. Where symptoms exist, they may include headaches, seizures, problems with vision, vomiting and mental changes. Other symptoms may include difficulty walking, speaking, with sensations, or unconsciousness. The cause of most brain tumors is unknown, though up to 4% of brain cancers may be caused by CT scan radiation. Uncommon risk factors include exposure to vinyl chloride, Epstein–Barr vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Neuro-Oncology
The ''Journal of Neuro-Oncology'' is a peer-reviewed medical journal covering cancer of the central nervous system. It was established in 1983 and is published 15 times per year by Springer Science+Business Media. It was originally published by Martinus Nijhoff Publishers and has been published by Springer since 2005. It is the oldest continuously published journal focused on the field of Neuro-Oncology. It is sponsored by the Tumor Section for the American Association of Neurological Surgeons and Congress of Neurological Surgeons. It is co-sponsored by the Society of British Neurological Surgeons, thEuropean Association of Neurosurgical Societies Section of Neuro-Oncology the Korean Neurosurgical Society, the Chinese Society for Neuro-Oncology (CSNO), the Grupo Interdisciplinario Mexicano de Investigacion en Neuro-Oncologia, thRadiosurgery Society thSociety for NeuroOncology Latin America thIndian Society of Neuro-Oncology and the Taiwan Society for Neuro-Oncology (TSNO). Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brachial Plexus
The brachial plexus is a network of nerves (nerve plexus) formed by the anterior rami of the lower four Spinal nerve#Cervical nerves, cervical nerves and first Spinal nerve#Thoracic nerves, thoracic nerve (cervical spinal nerve 5, C5, Cervical spinal nerve 6, C6, cervical spinal nerve 7, C7, cervical spinal nerve 8, C8, and thoracic spinal nerve 1, T1). This plexus extends from the spinal cord, through the cervicoaxillary canal in the neck, over the first rib, and into the axilla, armpit, it supplies Afferent nerve fiber, afferent and efferent nerve fibers to the chest, shoulder, arm, forearm, and hand. Structure The brachial plexus is divided into five ''roots'', three ''trunks'', six ''divisions'' (three anterior and three posterior), three ''cords'', and five ''branches''. There are five "terminal" branches and numerous other "pre-terminal" or "collateral" branches, such as the subscapular nerve, the thoracodorsal nerve, and the long thoracic nerve, that leave the plexus at vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lumbosacral Plexus
The anterior divisions of the lumbar nerves, sacral nerves, and coccygeal nerve form the lumbosacral plexus, the first lumbar nerve being frequently joined by a branch from the twelfth thoracic. For descriptive purposes this plexus is usually divided into three parts: * lumbar plexus The lumbar plexus is a web of nerves (a nerve plexus) in the lumbar region of the body which forms part of the larger lumbosacral plexus. It is formed by the divisions of the first four lumbar nerves (L1–L4) and from contributions of the su ... * sacral plexus * pudendal plexus Injuries to the lumbosacral plexus are predominantly witnessed as bone injuries. Lumbosacral trunk and sacral plexus palsies are common injury patterns. References External links * - "Lumbosacral Plexus" Additional Images File:Slide2Anat.JPG, Lumbosacral plexus Deep dissection. File:Slide4Anat.JPG, Lumbosacral plexus Deep dissection. Nerve plexus Nerves of the lower limb and lower torso {{Ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Metastasis
A brain metastasis is a cancer that has metastasis, metastasized (spread) to the brain from another location in the body and is therefore considered a brain tumor, secondary brain tumor. The metastasis typically shares a Cancer cell, cancer cell type with the original site of the cancer. Metastasis is the most common cause of brain cancer, as primary tumors that originate in the brain are less common. The most common sites of primary cancer which metastasize to the brain are lung, breast, colon, kidney, and skin cancer. Brain metastases can occur months or even years after the original or primary cancer is treated. Brain metastases have a poor prognosis for cure, but modern treatments allow patients to live months and sometimes years after the diagnosis. Symptoms and signs Because different parts of the brain are responsible for different functions, symptoms vary depending on the site of metastasis within the brain. However, brain metastases should be considered in any cancer pat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meninges
In anatomy, the meninges (; meninx ; ) are the three membranes that envelop the brain and spinal cord. In mammals, the meninges are the dura mater, the arachnoid mater, and the pia mater. Cerebrospinal fluid is located in the subarachnoid space between the arachnoid mater and the pia mater. The primary function of the meninges is to protect the central nervous system. Structure Dura mater The dura mater (), is a thick, durable membrane, closest to the Human skull, skull and vertebrae. The dura mater, the outermost part, is a loosely arranged, fibroelastic layer of cells, characterized by multiple interdigitating cell processes, no extracellular collagen, and significant extracellular spaces. The middle region is a mostly fibrous portion. It consists of two layers: the endosteal layer, which lies closest to the skull, and the inner meningeal layer, which lies closer to the brain. It contains larger blood vessels that split into the capillaries in the pia mater. It is composed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metastasis
Metastasis is a pathogenic agent's spreading from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary tumor, primary tumour heterogeneity, heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a Malignancy, malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells, known as circulating tumor cells (CTCs), are able to penetrate the walls of lymp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calvaria (skull)
The calvaria is the top part of the skull. It is the superior part of the neurocranium and covers the cranial cavity containing the brain. It forms the main component of the skull roof. The calvaria is made up of the superior portions of the frontal bone, occipital bone, and parietal bones. In the human skull, the suture (joint), sutures between the bones normally remain flexible during the first few years of postnatal development, and fontanelles are palpable. Premature complete ossification of these sutures is called craniosynostosis. In Latin, the word ''calvaria'' is used as a feminine noun with plural ''calvariae''; however, many medical texts incorrectly list the word as ''calvarium'', a neuter Latin noun with plural ''calvaria''. Structure The outer surface of the skull possesses a number of landmarks. The point at which the frontal bone and the two parietal bones meet is known as the bregma. The point at which the two parietal bones and the occipital bone meet is kn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edema
Edema (American English), also spelled oedema (British English), and also known as fluid retention, swelling, dropsy and hydropsy, is the build-up of fluid in the body's tissue (biology), tissue. Most commonly, the legs or arms are affected. Symptoms may include skin that feels tight, the area feeling heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include Chronic venous insufficiency, venous insufficiency, heart failure, kidney problems, hypoalbuminemia, low protein levels, liver problems, deep vein thrombosis, infections, kwashiorkor, angioedema, certain medications, and lymphedema. It may also occur in immobile patients (stroke, spinal cord injury, aging), or with temporary immobility such as prolonged sitting or standing, and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidural
Epidural administration (from Ancient Greek ἐπί, "upon" + '' dura mater'') is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord. The epidural route is used by physicians and nurse anesthetists to administer local anesthetic agents, analgesics, diagnostic medicines such as radiocontrast agent Radiocontrast agents are substances used to enhance the visibility of internal structures in X-ray-based imaging techniques such as computed tomography (contrast CT), projectional radiography, and fluoroscopy. Radiocontrast agents are typically iod ...s, and other medicines such as glucocorticoids. Epidural administration involves the placement of a catheter into the epidural space, which may remain in place for the duration of the treatment. The technique of intentional epidural administration of medication was first described in 1921 by the Spanish Aragonese people, Aragonese military surgeon Fidel Pagés. Epidural ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
