Maurice Nicolle
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Maurice Nicolle
Maurice Nicolle (1 March 1862 – 20 August 1932) was a French physician and microbiologist born in Rouen. He was the brother of biologist Charles Nicolle (1866–1936). He studied medicine in Rouen and Paris, becoming an interne to the hospitals of Paris in 1885. In 1887 he continued his internship under histologist Albert von Kölliker (1817–1905) at the University of Würzburg. In 1890 he supported his doctorate with a thesis on a study of diseases of the myocardium, titled ''Contribution à l'étude des affections du myocarde: les grandes scléroses cardiaques''. Afterwards he took courses in microbiology at the Pasteur Institute. From 1893 he studied biological staining techniques with Victor Morax (1866–1935), publishing two papers on the staining properties of ammoniated ruthenium oxychloride with Jean Cantacuzène (1863–1934). In 1893 he succeeded Waldemar Haffkine (1860–1930) as an instructor of microbiology at the Pasteur Institute, shortly afterwards bein ...
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Maurice Nicolle
Maurice Nicolle (1 March 1862 – 20 August 1932) was a French physician and microbiologist born in Rouen. He was the brother of biologist Charles Nicolle (1866–1936). He studied medicine in Rouen and Paris, becoming an interne to the hospitals of Paris in 1885. In 1887 he continued his internship under histologist Albert von Kölliker (1817–1905) at the University of Würzburg. In 1890 he supported his doctorate with a thesis on a study of diseases of the myocardium, titled ''Contribution à l'étude des affections du myocarde: les grandes scléroses cardiaques''. Afterwards he took courses in microbiology at the Pasteur Institute. From 1893 he studied biological staining techniques with Victor Morax (1866–1935), publishing two papers on the staining properties of ammoniated ruthenium oxychloride with Jean Cantacuzène (1863–1934). In 1893 he succeeded Waldemar Haffkine (1860–1930) as an instructor of microbiology at the Pasteur Institute, shortly afterwards bein ...
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Rinderpest
Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, lymphoid necrosis, and high mortality. Death rates during outbreaks were usually extremely high, approaching 100% in immunologically naïve populations. Rinderpest was mainly transmitted by direct contact and by drinking contaminated water, although it could also be transmitted by air. After a global eradication campaign starting in the mid-20th century, the last confirmed case of rinderpest was diagnosed in 2001. On 14 October 2010, the United Nations Food and Agriculture Organization (FAO) announced that field activities in the decades-long, worldwide campaign to eradicate the disease were ending, paving the way for a formal declaration in June 2011 of the global eradi ...
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Trypanocidal Agent
A trypanocidal agent is an antiprotozoal agent that acts upon Trypanosoma, trypanosome parasites. Examples include: * Aminoquinuride * benzonidazole * blasticidin S * DAPI * diminazene * diminazene aceturate * eflornithine * ethidium * isometamidium chloride * lonidamine * melaminylthioarsenate * melarsoprol * nifurtimox * pentamidine * posaconazole * puromycin * quinapyramine * salicylhydroxamic acid * suramin * tetraphenylporphine sulfonate Resistance 17 or 18 African countries had confirmed trypanocide resistance, resistant parasite populations, and that was up to 21. Multiple drug resistance, Multiply resistant populations are an increasing problem in the Adamawa Region of Cameroon and south east Mali. The Gibe River Valley in southwest Ethiopia showed universal resistance (in ''Trypanosoma congolense, T. congolense'' isolated from Boran cattle) between July 1989 and February 1993. This likely indicates a permanent loss of function in this area for the tested trypanocides, Dim ...
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Bayer Pharmaceutical
Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals; consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the Euro Stoxx 50 stock market index. Bayer was founded in 1863 in Barmen as a partnership between dye salesman Friedrich Bayer and dyer Friedrich Weskott. As was common in this era, the company was established as a dyestuffs producer. The versatility of aniline chemistry led Bayer to expand their business into other areas, and in 1899 Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. In 1904 Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. Other commonly known pro ...
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