Multidimensional Hierarchical Toolkit
The Multidimensional hierarchical toolkit ois a Linux-based, open-sourced, toolkit of portable software that supports very fast, flexible, multi-dimensional and hierarchical storage, retrieval and manipulation of information in databases ranging in size up to 256 terabytes. The package is written in C and C++ and is available under the GNU GPL/LGPL/Free Documentation licenses in source code form. The distribution kit contains demonstration implementations of network-capable, interactive text and sequence retrieval tools that function with very large genomic data bases and illustrate the toolkit's capability to manipulate massive data sets of genomic information. Distribution The toolkit is distributed as part of thMumps Compiler Versions exist for Linux, Cygwin, and Windows XP. Origins The toolkit is a solution to the problem of manipulating very large, character string indexed, multi-dimensional, sparse matrices. It is based on MUMPS (also referred to as M), a general pur ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Linux
Linux ( or ) is a family of open-source Unix-like operating systems based on the Linux kernel, an operating system kernel first released on September 17, 1991, by Linus Torvalds. Linux is typically packaged as a Linux distribution, which includes the kernel and supporting system software and libraries, many of which are provided by the GNU Project. Many Linux distributions use the word "Linux" in their name, but the Free Software Foundation uses the name "GNU/Linux" to emphasize the importance of GNU software, causing some controversy. Popular Linux distributions include Debian, Fedora Linux, and Ubuntu, the latter of which itself consists of many different distributions and modifications, including Lubuntu and Xubuntu. Commercial distributions include Red Hat Enterprise Linux and SUSE Linux Enterprise. Desktop Linux distributions include a windowing system such as X11 or Wayland, and a desktop environment such as GNOME or KDE Plasma. Distributions intended for ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Open-source License
An open-source license is a type of license for computer software and other products that allows the source code, blueprint or design to be used, modified and/or shared under defined terms and conditions. This allows end users and commercial companies to review and modify the source code, blueprint or design for their own customization, curiosity or troubleshooting needs. Open-source licensed software is mostly available free of charge, though this does not necessarily have to be the case. Licenses which only permit non-commercial redistribution or modification of the source code for personal use only are generally not considered as open-source licenses. However, open-source licenses may have some restrictions, particularly regarding the expression of respect to the origin of software, such as a requirement to preserve the name of the authors and a copyright statement within the code, or a requirement to redistribute the licensed software only under the same license (as in a copyl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Software
Software is a set of computer programs and associated software documentation, documentation and data (computing), data. This is in contrast to Computer hardware, hardware, from which the system is built and which actually performs the work. At the low level language, lowest programming level, executable code consists of Machine code, machine language instructions supported by an individual Microprocessor, processor—typically a central processing unit (CPU) or a graphics processing unit (GPU). Machine language consists of groups of Binary number, binary values signifying Instruction set architecture, processor instructions that change the state of the computer from its preceding state. For example, an instruction may change the value stored in a particular storage location in the computer—an effect that is not directly observable to the user. An instruction System call, may also invoke one of many Input/output, input or output operations, for example displaying some text on ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Databases
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an appli ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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C (programming Language)
C (''pronounced like the letter c'') is a General-purpose language, general-purpose computer programming language. It was created in the 1970s by Dennis Ritchie, and remains very widely used and influential. By design, C's features cleanly reflect the capabilities of the targeted CPUs. It has found lasting use in operating systems, device drivers, protocol stacks, though decreasingly for application software. C is commonly used on computer architectures that range from the largest supercomputers to the smallest microcontrollers and embedded systems. A successor to the programming language B (programming language), B, C was originally developed at Bell Labs by Ritchie between 1972 and 1973 to construct utilities running on Unix. It was applied to re-implementing the kernel of the Unix operating system. During the 1980s, C gradually gained popularity. It has become one of the measuring programming language popularity, most widely used programming languages, with C compilers avail ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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GNU GPL
The GNU General Public License (GNU GPL or simply GPL) is a series of widely used free software licenses that guarantee end users the four freedoms to run, study, share, and modify the software. The license was the first copyleft for general use and was originally written by the founder of the Free Software Foundation (FSF), Richard Stallman, for the GNU Project. The license grants the recipients of a computer program the rights of the Free Software Definition. These GPL series are all copyleft licenses, which means that any derivative work must be distributed under the same or equivalent license terms. It is more restrictive than the Lesser General Public License and even further distinct from the more widely used permissive software licenses BSD, MIT, and Apache. Historically, the GPL license family has been one of the most popular software licenses in the free and open-source software domain. Prominent free software programs licensed under the GPL include the Linux ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cygwin
Cygwin ( ) is a POSIX-compatible programming and runtime environment that runs natively on Microsoft Windows. Under Cygwin, source code designed for Unix-like operating systems may be compiled with minimal modification and executed. The Cygwin installation has a directory layout that is similar to the root file system of Unix-like systems, with familiar directories, such as /bin, /home, /etc, /usr, and /var. Cygwin installs with hundreds of command-line tools and other programs commonly found on a Unix-like system. Additionally, many applications may be installed from a packaging system. The terminal emulator Mintty is the default command-line interface provided to interact with the environment. Cygwin provides native integration of Windows-based applications. Thus it is possible to launch Windows applications from the Cygwin environment, as well as to use Cygwin tools and applications within the Windows operating context. Cygwin consists of two parts: a dynamic-link library ( ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Windows XP
Windows XP is a major release of Microsoft's Windows NT operating system. It was release to manufacturing, released to manufacturing on August 24, 2001, and later to retail on October 25, 2001. It is a direct upgrade to its predecessors, Windows 2000 for high-end and business users and Windows Me for home users, available for any devices running Windows NT 4.0, Windows 98, Windows 2000 and Windows Me that meet the new Windows XP system requirements. Development of Windows XP began in the late 1990s under the codename "Windows Neptune, Neptune", built on the Architecture of Windows NT#Kernel, Windows NT kernel explicitly intended for mainstream consumer use. An updated version of Windows 2000 was also initially planned for the business market. However, in January 2000, both projects were scrapped in favor of a single OS codenamed "Whistler", which would serve as a single platform for both consumer and business markets. As a result, Windows XP is the first consumer edition of W ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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MUMPS
MUMPS ("Massachusetts General Hospital Utility Multi-Programming System"), or M, is an imperative, high-level programming language with an integrated transaction processing key–value database. It was originally developed at Massachusetts General Hospital for managing hospital laboratory information systems. MUMPS technology has since expanded as the predominant database for health information systems and electronic health records in the United States. MUMPS-based information systems run over 40% of the hospitals in the U.S., run across all of the U.S. federal hospitals and clinics, and provide health information services for over 54% of patients across the U.S. A unique feature of the MUMPS technology is its integrated database language, allowing direct, high-speed read-write access to permanent disk storage. This provides tight integration of unlimited applications within a single database, and provides extremely high performance and reliability as an online transaction ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Charle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Boyer–Moore String-search Algorithm
In computer science, the Boyer–Moore string-search algorithm is an efficient string-searching algorithm that is the standard benchmark for practical string-search literature. It was developed by Robert S. Boyer and J Strother Moore in 1977. The original paper contained static tables for computing the pattern shifts without an explanation of how to produce them. The algorithm for producing the tables was published in a follow-on paper; this paper contained errors which were later corrected by Wojciech Rytter in 1980. The algorithm preprocesses the string being searched for (the pattern), but not the string being searched in (the text). It is thus well-suited for applications in which the pattern is much shorter than the text or where it persists across multiple searches. The Boyer–Moore algorithm uses information gathered during the preprocess step to skip sections of the text, resulting in a lower constant factor than many other string search algorithms. In general, the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Smith–Waterman Algorithm
The Smith–Waterman algorithm performs local sequence alignment; that is, for determining similar regions between two strings of nucleic acid sequences or protein sequences. Instead of looking at the Needleman–Wunsch algorithm, entire sequence, the Smith–Waterman algorithm compares segments of all possible lengths and Mathematical optimization, optimizes the similarity measure. The algorithm was first proposed by Temple F. Smith and Michael S. Waterman in 1981. Like the Needleman–Wunsch algorithm, of which it is a variation, Smith–Waterman is a dynamic programming algorithm. As such, it has the desirable property that it is guaranteed to find the optimal local alignment with respect to the scoring system being used (which includes the substitution matrix and the Gap penalty, gap-scoring scheme). The main difference to the Needleman–Wunsch algorithm is that negative scoring matrix cells are set to zero, which renders the (thus positively scoring) local alignments visible ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |