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Mitaban
Amitraz (development code BTS27419) is a non-systemic acaricide and insecticideCorta, E., Bakkali, A., Berrueta, L. A., Gallo, B., & Vicente, F. (1999). Kinetics and mechanism of amitraz hydrolysis in aqueous media by HPLC and GC-MS. Talanta, 48(1), 189-199 and has also been described as a scabicide. It was first synthesized by the Boots Co. in England in 1969.Harrison, I. R., et al. (1973). 1,3,5-Triazapenta-1, 4-dienes: Chemical aspects of a new group of pesticides. Pestic. Sci. 4: 901 Amitraz has been found to have an insect repellent effect, works as an insecticide and also as a pesticide synergist.PubChem Substance. Amitraz – Substance Summary. retrieved from https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=24868774#x332 Its effectiveness is traced back on alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis. Therefore, it leads to overexcitation and ...
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Acaricide
Acaricides are pesticides that kill members of the arachnid subclass '' Acari'', which includes ticks and mites. Acaricides are used both in medicine and agriculture, although the desired selective toxicity differs between the two fields. Terminology More specific words are sometimes used, depending upon the targeted group: * "Ixodicides" are substances that kill ticks. * "Miticides" are substances that kill mites. *The term scabicide is more narrow, and refers to agents specifically targeting '' Sarcoptes''. *The term "arachnicide" is more general, and refers to agents that target arachnids. This term is used much more rarely, but occasionally appears in informal writing. As a practical matter, mites are a paraphyletic grouping, and mites and ticks are usually treated as a single group. Examples Examples include: * Permethrin can be applied as a spray. The effects are not limited to mites: lice, cockroaches, fleas, mosquitos, and other insects will be affected. * Ivermec ...
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Mealybug
Mealybugs are insects in the family Pseudococcidae, unarmored scale insects found in moist, warm habitats. Of the more than 2,000 described species, many are considered pests as they feed on plant juices of greenhouse plants, house plants and subtropical trees and also act as a vector for several plant diseases. Some ants live in symbiotic relationships with them, protecting them from predators and feeding off the honeydew which they excrete. Description Mealybugs are sexually dimorphic: females appear as nymphs, exhibiting reduced morphology, and lack wings, although unlike many female scale insects, they often retain legs and can move. Males are smaller, gnat-like and have wings. Since mealybugs, as well as all other Hemiptera, are hemimetabolous insects, they do not undergo complete metamorphosis in the true sense of the word. However, male mealybugs exhibit a radical change during their life cycle, changing from wingless, ovoid nymphs to wasp-like flying adults. Meal ...
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CNS Depression
Central nervous system depression (or CNS depression) is a nervous system disorder characterized by a severely impaired physiological state in which patients may exhibit decreased rate of breathing, decreased heart rate, and loss of consciousness; in extreme cases, CNS depression can possibly lead to coma or death. Causes Central nervous system depression is generally caused by the improper or excessive use of depressant drugs such as opioids, barbiturates, benzodiazepines, general anesthetics, anticonvulsants, and certain sleep medications. These drugs, although useful for treating severe cases of depression that may manifest as CNS depression, can easily be misused. The medications above depress the functions of the spinal cord and brain, both vital components of the central nervous system. In cases of misuse due to addiction, accidents, or unregulated dosage increases, individuals can very easily slip into unconscious coma states because neural activity drops below safe level ...
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Carcinogen
A carcinogen () is any agent that promotes the development of cancer. Carcinogens can include synthetic chemicals, naturally occurring substances, physical agents such as ionizing and non-ionizing radiation, and biologic agents such as viruses and bacteria. Most carcinogens act by creating mutations in DNA that disrupt a cell's normal processes for regulating growth, leading to uncontrolled cellular proliferation. This occurs when the cell's DNA repair processes fail to identify DNA damage allowing the defect to be passed down to daughter cells. The damage accumulates over time. This is typically a multi-step process during which the regulatory mechanisms within the cell are gradually dismantled allowing for unchecked cellular division. The specific mechanisms for carcinogenic activity is unique to each agent and cell type. Carcinogens can be broadly categorized, however, as activation-dependent and activation-independent which relate to the agent's ability to engage dir ...
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USEPA
The Environmental Protection Agency (EPA) is an independent agency of the United States government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on December 2, 1970, after Nixon signed an executive order. The order establishing the EPA was ratified by committee hearings in the House and Senate. The agency is led by its administrator, who is appointed by the president and approved by the Senate. The current administrator is Lee Zeldin. The EPA is not a Cabinet department, but the administrator is normally given cabinet rank. The EPA has its headquarters in Washington, D.C. There are regional offices for each of the agency's ten regions, as well as 27 laboratories around the country. The agency conducts environmental assessment, research, and education. It has the responsibility of maintaining and enforcing national standards under a variety of environmental laws, in consultation with ...
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Conjunctivitis
Conjunctivitis, also known as pink eye or Madras eye, is inflammation of the conjunctiva, the thin, clear layer that covers the white surface of the eye and the inner eyelid. It makes the eye appear pink or reddish. Pain, burning, scratchiness, or itchiness may occur. The affected eye may have increased tears or be "stuck shut" in the morning. Swelling of the sclera may also occur. Itching is more common in cases due to allergies. Conjunctivitis can affect one or both eyes. The most common infectious causes in adults are viral, whereas in children bacterial causes predominate. The viral infection may occur along with other symptoms of a common cold. Both viral and bacterial cases are easily spread between people. Allergies to pollen or animal hair are also a common cause. Diagnosis is often based on signs and symptoms. Occasionally, a sample of the discharge is sent for microbial culture, culture. Prevention is partly by handwashing. Treatment depends on the underlying cause ...
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Alopecia
Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body. Typically at least the head is involved. The severity of hair loss can vary from a small area to the entire body. Inflammation or scarring is not usually present. Hair loss in some people causes psychological distress. Common types include male- or female-pattern hair loss, alopecia areata, and a thinning of hair known as telogen effluvium. The cause of male-pattern hair loss is a combination of genetics and male hormones; the cause of female pattern hair loss is unclear; the cause of alopecia areata is autoimmune; and the cause of telogen effluvium is typically a physically or psychologically stressful event. Telogen effluvium is very common following pregnancy. Less common causes of hair loss without inflammation or scarring include the pulling out of hair, certain medications including chemotherapy, HIV/AIDS, hypothyroidism, and malnutrition including iron def ...
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Mucosa
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is mostly of endodermal origin and is continuous with the skin at body openings such as the eyes, eyelids, ears, inside the nose, inside the mouth, lips, the genital areas, the urethral opening and the anus. Some mucous membranes secrete mucus, a thick protective fluid. The function of the membrane is to stop pathogens and dirt from entering the body and to prevent bodily tissues from becoming dehydrated. Structure The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. Mucous membranes line the digestive, respiratory and rep ...
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Demodicosis
Demodicosis , also called Demodex folliculitis in humans and demodectic mange () or red mange in animals, is caused by a sensitivity to and overpopulation of ''Demodex'' as the host's immune system is unable to keep the mites under control. ''Demodex'' is a genus of mite in the family Demodecidae. The mites are specific to their hosts, and each mammal species is host to one or two unique species of ''Demodex'' mites. Therefore, demodicosis cannot be transferred across species and has no zoonotic potential. Signs and symptoms Humans Demodicosis in humans is usually caused by '' Demodex folliculorum'' and may have a rosacea-like appearance. Common symptoms include hair loss, itching, and inflammation. An association with pityriasis folliculorum has also been described. Demodicosis is most often seen in folliculitis (inflammation of the hair follicles of the skin). Depending on the location, it may result in small pustules (pimples) at the base of a hair shaft on inflamed, co ...
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Lice
Louse (: lice) is the common name for any member of the infraorder Phthiraptera, which contains nearly 5,000 species of wingless parasitic insects. Phthiraptera was previously recognized as an order, until a 2021 genetic study determined that they are a highly modified lineage of the order Psocodea, whose members are commonly known as booklice, barklice or barkflies. Lice are obligate parasites, living externally on warm-blooded hosts, which include every species of bird and mammal, except for monotremes, pangolins, and bats. Chewing lice live among the hairs or feathers of their host and feed on skin and debris, whereas sucking lice pierce the host's skin and feed on blood and other secretions. They usually spend their whole life on a single host, cementing their eggs, called nits, to hairs or feathers. The eggs hatch into nymphs, which moult three times before becoming fully grown, a process that takes about four weeks. Humans host two species of louse—the head lou ...
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Demodex
''Demodex'' is a genus of tiny mites that live in or near hair follicles of mammals. Around 65 species of ''Demodex'' are known. Two species live on humans: ''Demodex folliculorum'' and ''Demodex brevis'', both frequently referred to as eyelash mites, alternatively face mites or skin mites. Different species of animals host different species of ''Demodex''. ''Demodex#D. canis, Demodex canis'' lives on the domestic dog. The presence of ''Demodex'' species on mammals is common and usually does not cause any symptoms. ''Demodex'' is derived from Greek language, Greek () and , δηκός (, ''dēkós'') . Notable species ''D. folliculorum'' and ''D. brevis'' ''Demodex folliculorum'' and ''D. brevis'' are typically found on humans. The former was first described in 1842 by German physician and dermatologist Gustav Simon (physician), Gustav Simon, with English biologist Richard Owen naming the genus ''Demodex'' the following year. ''Demodex brevis'' was identified as separate in 1 ...
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Ectoparasiticide
An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. These drugs are used to kill the parasites that live on the body surface. Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton are well known ectoparasiticides. Additionally, ectoparasiticides have been used to safely contaminate rhinoceros horns with hopes of it deterring the demand for these horns on the black market. Variants Permethrin Broad-spectrum and potent pyrethroid insecticide and is most convenient for both scabies and lice. First choice drug. Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis. Additional information about treatment failure rates amongst medications used to treat ectopara ...
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