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Mendelian Inheritance
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. These principles were initially controversial. When Mendel's theories were integrated with the Boveri–Sutton chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics. Ronald Fisher combined these ideas with the theory of natural selection in his 1930 book '' The Genetical Theory of Natural Selection'', putting evolution onto a mathematical footing and forming the basis for population genetics within the modern evolutionary synthesis. History The principles of Mendelian inheritance were named for and first derived by Gregor Johann Mendel, a nineteenth-century Moravian monk who formulated his ideas after conducting simple hybridization experiments with pea p ...
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Gregor Mendel
Gregor Johann Mendel Order of Saint Augustine, OSA (; ; ; 20 July 1822 – 6 January 1884) was an Austrian Empire, Austrian biologist, meteorologist, mathematician, Augustinians, Augustinian friar and abbot of St Thomas's Abbey, Brno, St. Thomas' Abbey in Brno (Brünn), Margraviate of Moravia. Mendel was born in a Sudeten Germans, German-speaking family in the Austrian Silesia, Silesian part of the Austrian Empire (today's Czech Republic) and gained posthumous recognition as the founder of the modern science of genetics. Though farmers had known for millennia that crossbreeding of animals and plants could favor certain desirable trait (biological), traits, Mendel's pea plant experiments conducted between 1856 and 1863 established many of the rules of biological inheritance, heredity, now referred to as the laws of Mendelian inheritance. Mendel worked with seven characteristics of Pea, pea plants: plant height, pod shape and color, seed shape and color, and flower position and c ...
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Moravians
Moravians ( or Colloquialism, colloquially , outdated ) are a West Slavs, West Slavic ethnic group from the Moravia region of the Czech Republic, who speak the Moravian dialects of Czech language, Czech or Czech language#Common Czech, Common Czech or a mixed form of both. Along with the Silesians of the Czech Republic, a part of the population to identify ethnically as Moravian has registered in Czech censuses since 1991. The figure has fluctuated and in the 2011 census, 6.01% of the Czech population declared Moravian as their ethnicity. Smaller pockets of people declaring Moravian ethnicity are also native to neighboring Slovakia. Etymology A certain ambiguity in Czech language, Czech derives from the fact that it distinguishes between (Bohemia proper) and (Czech Republic as a whole), but the corresponding adjective and noun designating an inhabitant and/or a member of a nation can be related to either of them. The adjective and the noun ('Bohemian') carry only the m ...
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Cell (biology)
The cell is the basic structural and functional unit of all life, forms of life. Every cell consists of cytoplasm enclosed within a Cell membrane, membrane; many cells contain organelles, each with a specific function. The term comes from the Latin word meaning 'small room'. Most cells are only visible under a light microscope, microscope. Cells Abiogenesis, emerged on Earth about 4 billion years ago. All cells are capable of Self-replication, replication, protein synthesis, and cell motility, motility. Cells are broadly categorized into two types: eukaryotic cells, which possess a Cell nucleus, nucleus, and prokaryotic, prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular organism, multicellular, such as some algae, plants, animals, and fungi. Eukaryotic cells contain organelles including Mitochondrion, mitochondria, which ...
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Chromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most important of these proteins are the histones. Aided by chaperone proteins, the histones bind to and condense the DNA molecule to maintain its integrity. These eukaryotic chromosomes display a complex three-dimensional structure that has a significant role in transcriptional regulation. Normally, chromosomes are visible under a light microscope only during the metaphase of cell division, where all chromosomes are aligned in the center of the cell in their condensed form. Before this stage occurs, each chromosome is duplicated ( S phase), and the two copies are joined by a centromere—resulting in either an X-shaped structure if the centromere is located equatorially, or a two-armed structure if the centromere is located distally; the jo ...
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Heredity
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics. Overview In humans, eye color is an example of an inherited characteristic: an individual might inherit the "brown-eye trait" from one of the parents. Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype. The complete set of observable traits of the structure and behavior of an organism is called its phenotype. These traits arise from the interaction of the organism's genotype with the environment. As a result, many aspects of an organism's phenotype are not inherited. For example, ...
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Allele
An allele is a variant of the sequence of nucleotides at a particular location, or Locus (genetics), locus, on a DNA molecule. Alleles can differ at a single position through Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP), but they can also have insertions and deletions of up to several thousand base pairs. Most alleles observed result in little or no change in the function or amount of the gene product(s) they code or regulate for. However, sometimes different alleles can result in different observable phenotypic traits, such as different pigmentation. A notable example of this is Gregor Mendel's discovery that the white and purple flower colors in pea plants were the result of a single gene with two alleles. Nearly all multicellular organisms have two sets of chromosomes at some point in their biological life cycle; that is, they are diploid. For a given locus, if the two chromosomes contain the same allele, they, and the organism, are homozygous with re ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (bi ...
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Erich Von Tschermak
Erich Tschermak, Edler von Seysenegg (15 November 1871 – 11 October 1962) was an Austrian agronomist who developed several new disease-resistant crops, including wheat-rye and oat hybrids. He was a son of the Moravia-born mineralogist Gustav Tschermak von Seysenegg. His maternal grandfather was the botanist, Eduard Fenzl, who taught Gregor Mendel botany during his student days in Vienna. He received his doctorate from the University of Halle, Germany, in 1896. Tschermak accepted a teaching position at the University of Agricultural Sciences Vienna in 1901, and became professor there five years later, in 1900. Von Tschermak is one of four men—see also Hugo de Vries, Carl Correns and William Jasper Spillman—who independently rediscovered Gregor Mendel's work on genetics. Von Tschermak published his findings in June, 1900. His works in genetics were largely influenced by his brother Armin von Tschermak-Seysenegg. Decorations and awards * Member Royal Swedish Academy ...
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Quantitative Trait Locus
A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. This is often an early step in identifying the actual genes that cause the trait variation. Definition A quantitative trait locus (QTL) is a region of DNA which is associated with a particular phenotypic trait, which varies in degree and which can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment. . These QTLs are often found on different chromosomes. The number of QTLs which explain variation in the phenotypic trait indicates the genetic architecture of a trait. It may indicate that plant height is controlled by many genes of small effect, or by a few genes of large effect. Typically, QTLs underlie continuous traits (those traits which vary continuou ...
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Complex Traits
Complex traits are phenotypes that are controlled by two or more genes and do not follow Mendel's Law of Dominance. They may have a range of expression which is typically continuous. Both environmental and genetic factors often impact the variation in expression. Human height is a continuous trait meaning that there is a wide range of heights. There are an estimated 50 genes that affect the height of a human. Environmental factors, like nutrition, also play a role in a human's height. Other examples of complex traits include: crop yield, plant color, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits. Complex traits are also known as polygenic traits and multigenic traits. The existence of complex traits, which are far more common than Mendelian traits, represented a significant challenge to the acceptance of Mend ...
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Blending Inheritance
Blending inheritance is an obsolete theory in biology from the 19th century. The theory is that the progeny inherits any characteristic as the average of the parents' values of that characteristic. As an example of this, a crossing of a red flower variety with a white variety of the same species would yield pink-flowered offspring. Charles Darwin's theory of inheritance by pangenesis, with contributions to egg or sperm from every part of the body, implied blending inheritance. His reliance on this mechanism led Fleeming Jenkin to attack Darwin's theory of natural selection on the grounds that blending inheritance would average out any novel beneficial characteristic before selection had time to act. Blending inheritance was discarded with the general acceptance of particulate inheritance during the development of modern genetics, after . History Darwin's pangenesis Charles Darwin developed his theory of evolution by natural selection on the basis of an understanding of ...
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Brno
Brno ( , ; ) is a Statutory city (Czech Republic), city in the South Moravian Region of the Czech Republic. Located at the confluence of the Svitava (river), Svitava and Svratka (river), Svratka rivers, Brno has about 403,000 inhabitants, making it the second-largest city in the Czech Republic after the capital, Prague, and one of the List of cities in the European Union by population within city limits, 100 largest cities of the European Union. The Brno metropolitan area has approximately 730,000 inhabitants. Brno is the former capital city of Moravia and the political and cultural hub of the South Moravian Region. It is the centre of the Judiciary of the Czech Republic, Czech judiciary, with the seats of the Constitutional Court of the Czech Republic, Constitutional Court, the Supreme Court of the Czech Republic, Supreme Court, the Supreme Administrative Court of the Czech Republic, Supreme Administrative Court, and the Supreme Public Prosecutor's Office, and a number of state ...
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