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Maurice Sanford Fox
Maurice Sanford Fox (October 11, 1924 – January 26, 2020) was an American geneticist and molecular biologist, and professor of biology at the Massachusetts Institute of Technology (MIT), where he served as department chair between 1985 and 1989. His pioneering investigations of bacterial transformation helped illuminate the mechanisms by which donor DNA enters and is integrated into a host cell. His research also contributed to our understanding of mechanisms of DNA mutation, recombination, and mismatch repair more generally. Ancillary activities include his critical role in the establishment of the Council for a Livable World. He was married to photo researcher Sally Fox, who died in 2006, for over 50 years, and has three sons (Jonathan, Gregory, and Michael). Fox died in January 2020 at the age of 95. Youth and Education Maurice Fox (Maury) was born of poor Russian Jewish immigrants and spent his formative years living in New York City. He is the brother of Evelyn Fox Ke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City
New York, often called New York City or NYC, is the most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous megacities, and over 58 million people live within of the city. New York City is a global cultural, financial, entertainment, and media center with a significant influence on commerce, health care and life sciences, research, technology, educa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Banesh Hoffmann
Banesh Hoffmann (6 September 1906 – 5 August 1986) was a British mathematician and physicist known for his association with Albert Einstein. Life Banesh Hoffmann was born in Richmond, Surrey, on 6 September 1906. He studied mathematics and theoretical physics at the University of Oxford, where he earned a Bachelor of Arts degree and went on to earn his doctorate at Princeton University. While at the Institute for Advanced Study in Princeton, Hoffmann collaborated with Einstein and Leopold Infeld on the classic paper ''Gravitational Equations and the Problem of Motion.'' Einstein's original work on general relativity was based on two ideas. The first was the equation of motion: that a particle would follow the shortest path in four-dimensions space-time. The second was how matter affects the geometry of space-time. What Einstein, Infeld, and Hoffmann showed was that the equation of motion followed directly from the field equation that defined the geometry (see main arti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UNESCO
The United Nations Educational, Scientific and Cultural Organization is a specialized agency of the United Nations (UN) aimed at promoting world peace and security through international cooperation in education, arts, sciences and culture. It has 193 member states and 12 associate members, as well as partners in the non-governmental, intergovernmental and private sector. Headquartered at the World Heritage Centre in Paris, France, UNESCO has 53 regional field offices and 199 national commissions that facilitate its global mandate. UNESCO was founded in 1945 as the successor to the League of Nations's International Committee on Intellectual Cooperation.English summary). Its constitution establishes the agency's goals, governing structure, and operating framework. UNESCO's founding mission, which was shaped by the Second World War, is to advance peace, sustainable development and human rights by facilitating collaboration and dialogue among nations. It pursues this objec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, '' Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commerc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Academy Of Microbiology
The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It was founded in 1899. The Society publishes a variety of scientific journals, textbooks, and other educational materials related to microbiology and infectious diseases. ASM organizes annual meetings, as well as workshops and professional development opportunities for its members. History ASM was founded in 1899 under the name the "Society of American Bacteriologists." In December 1960, it was renamed the "American Society for Microbiology." Mission ASM's mission is "to promote and advance the microbial sciences." The society seeks to accomplish this mission through: * Publishing highly-cited publications * Running multi-disciplinary meetings * Deploying resources and expertise around the world * Advocating for scientific research * Fosteri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fogarty International Center
The John E. Fogarty International Center was founded in 1968 by US President Lyndon Johnson at the National Institutes of Health to support international medical and behavioral research and to train international researchers. History On July 1, 1968, President Lyndon Johnson issued an Executive Order establishing the John E. Fogarty International Center for Advanced Study in the Health Sciences at the National Institutes of Health (NIH) in order to support international medical and behavioral research and to train international researchers. In March 2017, the Trump Administration proposed cuts to the NIH budget, including elimination of the Fogarty Center, saving $69 million.Donald G. McNeil JrTrump Plan Eliminates a Global Sentinel Against Disease, Experts Warn New York Times, 17 March 2017, retrieved 12 July 2018 References {{authority control National Institutes of Health, Fogarty International Center Medical research institutes in the United States, Medical resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide sci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institute Of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Sciences (NAS), National Academy of Engineering (NAE), and the National Research Council (NRC). The National Academy of Medicine provides national and international advice on issues relating to health, medicine, health policy, and biomedical science. It aims to provide unbiased, evidence-based, and authoritative information and advice concerning health and science policy to policy-makers, professionals, leaders in every sector of society, and the public at large. Operating outside the framework of the U.S. federal government, it relies on a volunteer workforce of scientists and other experts, operating under a formal peer-review system. As a national academy, the organization ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Bioethics Committee
The International Bioethics Committee (IBC) of UNESCO is a body composed of 36 independent experts from all regions and different disciplines (mainly medicine, genetics, law, and philosophy) that follows progress in the life sciences and its applications in order to ensure respect for human dignity and human rights. It was created in 1993 by Dr Federico Mayor Zaragoza, General Director of UNESCO at that time. It has been prominent in developing Declarations with regard to norms of bioethics that are regarded as soft law but are nonetheless influential in shaping the deliberations, for example, of research ethics committees (or Institutional review board) and health policy. Universal Declaration on Human Genome and Human Rights In 1993, the IBC was entrusted with the task of preparing an international instrument on the human genome, the Universal Declaration on the Human Genome and Human Rights, which was adopted by the General Conference of UNESCO in 1997 and endorsed by the Ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miroslav Radman
Miroslav Radman (born April 30, 1944) is a Croatian biologist. Biography Radman was born in Split, PR Croatia, Yugoslavia. From 1962–1967 he studied experimental biology, physical chemistry and molecular biology at the University of Zagreb and in 1969 he obtained a doctorate degree in molecular biology at the Free University of Brussels. He spent the next three years at Harvard University as a postdoctoral researcher. From 1973 until 1983 he was Professor of Molecular Biology at the Free University of Brussels and from 1983 until 1998 the Research Director at the French Centre for Scientific Research at the University of Paris 7. He is now a professor of cellular biology at the Faculté de Médecine – Necker, Université Paris V, Paris, France. In 2002 he became a full member of the French Academy of Sciences, the first Croat to do so in the Academy's history. Radman is a co-founder of the Mediterranean Institute For Life Sciences located in Split, Croatia. Scientific work ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SOS Response
The SOS response is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis is induced. The system involves the RecA protein ( Rad51 in eukaryotes). The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the repressor ( LexA) of SOS response genes thereby inducing the response. It is an error-prone repair system that contributes significantly to DNA changes observed in a wide range of species. Discovery The SOS response was discovered and named by Miroslav Radman in 1975. Mechanism During normal growth, the SOS genes are negatively regulated by LexA repressor protein dimers. Under normal conditions, LexA binds to a 20-bp consensus sequence (the SOS box) in the operator region for those genes. Some of these SOS genes are expressed at certain levels even in the repressed state, according to the affinity of LexA for their SOS box. Activation of the SOS genes occurs after DNA damage by the accumulat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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