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Mass Deworming
Mass deworming, is one of the preventive chemotherapy tools, used to treat large numbers of people, particularly children, for worm infections notably soil-transmitted helminthiasis, and schistosomiasis in areas with a high prevalence of these conditions. It involves treating everyone – often all children who attend schools, using existing infrastructure to save money – rather than testing first and then only treating selectively. Serious side effects have not been reported when administering the medication to those without worms, and testing for the infection is many times more expensive than treating it. Therefore, for the same amount of money, mass deworming can treat more people more cost-effectively than selective deworming. Mass deworming is one example of mass drug administration. Mass deworming of children can be carried out by administering mebendazole and albendazole which are two types of anthelmintic drug. The cost of providing one tablet every six to twelve mont ...
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Anthelmintic
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals, particularly small ruminants such as goats and sheep. Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries. Anthelmintics are also used for mass deworming of livestock. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Many early treatments were herbal, such as the oil of herbs of the genus '' Chenopodium'' that were given as anthelmintic treatment for ...
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Schistosomiasis Control Initiative
Unlimit Health (previously known as SCI Foundation and as the Schistosomiasis Control Initiative) is an international organisation working to end parasitic disease. The organisation partners with affected countries, sharing evidence and expertise to eliminate preventable infections, through technical and financial support to ministries of health, in line with their strategies and plans, to strengthen health systems within affected communities. Unlimit Health’s area of focus is the elimination of schistosomiasis and soil-transmitted helminthiases (intestinal worms). Parasitic worms can have a hugely detrimental effect on individuals, including reduced productivity, internal organ damage, impaired child development, reduced school attendance, increased risk of HIV in women and infertility. Unlimit Health engages in global and regional forums that aim to tackle parasitic infections, providing technical expertise to global bodies such as the World Health Organization (WHO). It h ...
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Disability-adjusted Life Year
A disability-adjusted life year (DALY) is a measure of overall disease burden, representing a year lost due to ill-health, disability, or early death. It was developed in the 1990s as a way of comparing the overall health and life expectancy of different countries. The concept has become more common in the field of public health and health impact assessment (HIA). It combines both potential years of life lost due to premature death ( mortality) and to poor health or disability ( morbidity) into a single metric. DALY, QALY and HALY DALY is closely related to QALY and HALY. A QALY (quality-adjusted life year) measures both the length and quality of life. QALYs are commonly used to assess the cost-effectiveness of medical or public health interventions and to guide decisions aimed at improving social welfare. However, QALYs measure only the benefit of medical interventions, not the overall burden of disease. Like DALY, HALY (health-adjusted life years) assesses the combined effec ...
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Campbell Collaboration
The Campbell Collaboration is a non-profit organisation that promotes evidence-based decisions and policy through the production of systematic reviews and other types of evidence synthesis. Campbell is composed of coordinating groups that coordinate the production of systematic reviews and evidence gap maps in the following areas: Ageing, Business & Management, Children & Young Persons Wellbeing, Climate Solutions, Crime & Justice, Disability, Education, International Development, Knowledge Translation & Implementation, Methods and Social Welfare. It is a sister initiative of Cochrane. The CEO is Will Moy, who was formerly Chief Executive of Full Fact. The current president of the board of directors is Jeremy Grimshaw. Campbell reviews are published in ''Campbell Systematic Reviews'', an open access journal committed to publishing systematic reviews as well as methods research papers, and evidence and gap maps. The Editor-In-Chief is Vivian Welch from the University of Ottawa. ...
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Randomized Controlled Trials
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures, diets or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing standard of care; these are then termed the 'exper ...
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Evidence-based Medicine
Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients. It means integrating individual clinical expertise with the best available external clinical evidence from systematic research." The aim of EBM is to integrate the experience of the clinician, the values of the patient, and the best available scientific information to guide decision-making about clinical management. The term was originally used to describe an approach to teaching the practice of medicine and improving decisions by individual physicians about individual patients. The EBM Pyramid is a tool that helps in visualizing the hierarchy of evidence in medicine, from least authoritative, like expert opinions, to most authoritative, like systematic reviews. Adoption of evidence-based medicine is necessary in a human Rights-based approach to development, rights-based approach to public health and a precondition ...
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Cochrane Review
Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has over volunteer experts from around the world. The group conducts systematic reviews of healthcare interventions and diagnostic tests and publishes them in the Cochrane Library. While Cochrane reviews typically focus on randomized controlled trials, some reviews, particularly in areas such as public and occupational health, also incorporate other study designs. These may include non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. According to the Library, articles are available via one-click access, though some may require registration or a subscription. History Cochrane, previ ...
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World Bank
The World Bank is an international financial institution that provides loans and Grant (money), grants to the governments of Least developed countries, low- and Developing country, middle-income countries for the purposes of economic development. The World Bank is the collective name for the International Bank for Reconstruction and Development (IBRD) and International Development Association (IDA), two of five international organizations owned by the World Bank Group. It was established along with the International Monetary Fund at the 1944 Bretton Woods Conference. After a slow start, its first loan was to France in 1947. In its early years, it primarily focused on rebuilding Europe. Over time, it focused on providing loans to developing world countries. In the 1970s, the World Bank re-conceptualized its mission of facilitating development as being oriented around poverty reduction. For the last 30 years, it has included NGOs and environmental groups in its loan portfolio. Its ...
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Hand Washing
Hand washing (or handwashing), also known as hand hygiene, is the act of cleaning one's hands with soap, soap or handwash and water to remove viruses, bacteria, microorganisms, dirt, grease, and other harmful or unwanted substances stuck to the hands. Drying of the washed hands is part of the process as wet and moist hands are more easily recontaminated. If soap and water are unavailable, hand sanitizer that is at least 60% (v/v) Alcohol (chemistry), alcohol in water can be used as long as hands are not visibly excessively dirty or greasy. Hand hygiene is central to preventing the spread of Infection, infectious diseases in home and everyday life settings. The World Health Organization (WHO) recommends washing hands for at least 20 seconds before and after certain activities. These include the five critical times during the day where washing hands with soap is important to reduce Fecal–oral route, fecal-oral transmission of disease: after using the Toilet (room), toilet (for ...
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WASH
Wash or the Wash may refer to: Industry and sanitation * WASH or WaSH, "water, sanitation and hygiene", three related public health issues * Wash (distilling), the liquid produced by the fermentation step in the production of distilled beverages * Lime wash or whitewash, a low-cost industrial paint Places England * The Wash, the square-mouthed estuary on the northwest margin of East Anglia in England * Wash, Derbyshire, a hamlet in Derbyshire, England United States * Wash Creek, a stream in North Carolina * Washington (state), U.S. state sometimes abbreviated as "Wash." * Blanchard Park, Pomona College, California, commonly known as the Wash * Clio, California, formerly known as Wash People * Wash (pharaoh), an ancient Egyptian predynastic ruler * Wash (singer), an American singer * Wash Hendry (1838–1914), also known as George W. Hendry, American Florida early settler * Martha Wash (born 1953), American singer-songwriter and actress * Todd Wash (born 1968), American foot ...
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Praziquantel
Praziquantel, sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish. In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, echinococcosis, paragonimiasis, fasciolopsiasis, and fasciolosis. It should not be used for worm infections of the eye. It is taken by mouth. Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. While it may be used during pregnancy, it is not recommended for use during breastfeeding. Praziquantel is in the anthelmintic class of medications. It works partly by affecting the function of the worm's sucker. Praziquantel was approved for medical use in the United States in 1982, and in the European Union in April 2025. It is on the World Health Organization's List of Essential Medicines. Medic ...
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Schistosoma
''Schistosoma'' is a genus of trematodes, commonly known as blood flukes. They are Parasitism, parasitic flatworms responsible for a highly significant group of infections in humans termed ''schistosomiasis'', which is considered by the World Health Organization to be the second-most socioeconomically devastating parasitic disease (after malaria), infecting millions worldwide. Adult flatworms parasitize blood capillaries of either the mesenteries or plexus of the bladder, depending on the infecting species. They are unique among trematodes and any other flatworms in that they are Dioecy, dioecious with distinct sexual dimorphism between male and female. Thousands of eggs are released and reach either the bladder or the intestine (according to the infecting species), and these are then excreted in urine or feces to fresh water. Larvae must then pass through an intermediate snail Host (biology), host before the next larval stage of the parasite emerges that can infect a new mammal ...
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