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Marfan Foundation
The Marfan Foundation (formerly National Marfan Foundation, NMF) is a non-profit organization in the United States established to raise awareness and promote research on treatment of Marfan syndrome and related disorders. The Foundation provides information about Marfan syndrome and funds research for the purposes of saving lives and improving the quality of life for people affected by the condition which is a genetic connective tissue disorder. The Foundation also lobbies Congress to fund Marfan syndrome research and engages in its own fundraising activities. History The Foundation was established in 1981 by Priscilla Ciccariello, who lost a husband and son to the disorder, and Reed E. Pyeritz, MD, a geneticist at Johns Hopkins Hospital. In addition to providing grants for research on Marfan syndrome, the foundation raises awareness of the condition, which often goes undiagnosed, among health care providers and the public. The Foundation hosts an annual conference, has dozens of ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marfan Syndrome
Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. Those with the condition tend to be tall and thin, with long arms, legs, fingers, and toes. They also typically have exceptionally flexible joints and abnormally curved spines. The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm. The lungs, eyes, bones, and the covering of the spinal cord are also commonly affected. The severity of the symptoms is variable. MFS is caused by a mutation in '' FBN1'', one of the genes that makes fibrillin, which results in abnormal connective tissue. It is an autosomal dominant disorder. In about 75% of cases, it is inherited from a parent with the condition, while in about 25% it is a new mutation. Diagnosis is often based on the Ghent criteria. There is no known cure for MFS. Many of those with the disorder have a normal life expectancy with proper treatment. Management ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1981 Establishments In New York (state)
Events January * January 1 ** Greece enters the European Economic Community, predecessor of the European Union. ** Palau becomes a self-governing territory. * January 10 – Salvadoran Civil War: The FMLN launches its first major offensive, gaining control of most of Morazán and Chalatenango departments. * January 15 – Pope John Paul II receives a delegation led by Polish Solidarity leader Lech Wałęsa at the Vatican. * January 20 – Iran releases the 52 Americans held for 444 days, minutes after Ronald Reagan is sworn in as the 40th President of the United States, ending the Iran hostage crisis. * January 21 – The first DeLorean automobile, a stainless steel sports car with gull-wing doors, rolls off the production line in Dunmurry, Northern Ireland. * January 24 – An earthquake of magnitude in Sichuan, China, kills 150 people. Japan suffers a less serious earthquake on the same day. * January 25 – In South Africa the largest part of the town Laingsbu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organizations Established In 1981
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Charities In The United States
Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organization''– ''Basic Documents'', Forty-fifth edition, Supplement, October 2006. A variety of definitions have been used for different purposes over time. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive stress. Some factors affecting health are due to individual choices, such as whether to engage in a high-risk behavior, while others are due to structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are beyond both individual and group choices, such as genetic disorders. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connective Tissue Disease
A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hollywood, Florida
Hollywood is a city in southern Broward County, Florida, United States, located between Fort Lauderdale and Miami. As of July 1, 2019, Hollywood had a population of 154,817. Founded in 1925, the city grew rapidly in the 1950s and 1960s, and is now the 12th-largest city in Florida. Hollywood is a principal city of the Miami metropolitan area, which was home to an estimated 6,012,331 people at the 2015 census. The average temperature is between . History In 1920, Joseph Young arrived in South Florida to create his own "Dream City in Florida". His vision included the beaches of the Atlantic Ocean stretching westward with man-made lakes, infrastructure, roads, and the Intracoastal Waterway. He wanted to include large parks, schools, churches, and golf courses; these were all industries and activities that were very important to Young's life. After Young spent millions of dollars on the construction of the city, he was elected as the first mayor in 1925. This new town quickly became h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Costa Mesa, California
Costa Mesa (; Spanish for " Table Coast") is a city in Orange County, California. Since its incorporation in 1953, the city has grown from a semi-rural farming community of 16,840 to an urban area including part of the South Coast Plaza–John Wayne Airport edge city, one of the region's largest commercial clusters, with an economy based on retail, commerce, and light manufacturing. The city is home to the two tallest skyscrapers in Orange County. The population was 111,918 at the 2020 census. History Members of the Tongva and Acjachemen nations long inhabited the area. The Tongva villages of Lupukngna, at least 3,000 years old, and the shared Tongva and Acjachemen village of Genga, at least 9,500 years old, were located in the area on the bluffs along the Santa Ana River. After the 1769 expedition of Gaspar de Portolà, a Spanish expedition led by Junípero Serra named the area Vallejo de Santa Ana (Valley of Saint Anne). On November 1, 1776, Mission San Juan Capistr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walk For Victory
Walking (also known as ambulation) is one of the main gaits of terrestrial locomotion among legged animals. Walking is typically slower than running and other gaits. Walking is defined by an 'inverted pendulum' gait in which the body vaults over the stiff limb or limbs with each step. This applies regardless of the usable number of limbs—even arthropods, with six, eight, or more limbs, walk. Difference from running The word ''walk'' is descended from the Old English ''wealcan'' "to roll". In humans and other bipeds, walking is generally distinguished from running in that only one foot at a time leaves contact with the ground and there is a period of double-support. In contrast, running begins when both feet are off the ground with each step. This distinction has the status of a formal requirement in competitive walking events. For quadrupedal species, there are numerous gaits which may be termed walking or running, and distinctions based upon the presence or absence of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-profit Organization
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworthiness, honesty, and openness to ev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Victor A
The name Victor or Viktor may refer to: * Victor (name), including a list of people with the given name, mononym, or surname Arts and entertainment Film * ''Victor'' (1951 film), a French drama film * ''Victor'' (1993 film), a French short film * ''Victor'' (2008 film), a 2008 TV film about Canadian swimmer Victor Davis * ''Victor'' (2009 film), a French comedy * ''Victor'', a 2017 film about Victor Torres by Brandon Dickerson * ''Viktor'' (film), a 2014 Franco/Russian film Music * ''Victor'' (album), a 1996 album by Alex Lifeson * "Victor", a song from the 1979 album ''Eat to the Beat'' by Blondie Businesses * Victor Talking Machine Company, early 20th century American recording company, forerunner of RCA Records * Victor Company of Japan, usually known as JVC, a Japanese electronics corporation originally a subsidiary of the Victor Talking Machine Company ** Victor Entertainment, or JVCKenwood Victor Entertainment, a Japanese record label ** Victor Interactive So ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-locations It is one of the largest pharmaceutical companies in the world. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. In March 1996, the companies Ciba-Geigy and Sandoz merged to form Novartis; the pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. Other Ciba-Geigy and Sandoz businesses were sold, or, like Ciba Specialty Chemicals, spun off as independent companies. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
