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Lutetium
Lutetium is a chemical element; it has symbol Lu and atomic number 71. It is a silvery white metal, which resists corrosion in dry air, but not in moist air. Lutetium is the last element in the lanthanide series, and it is traditionally counted among the rare earth elements; it can also be classified as the first element of the 6th-period transition metals. Lutetium was independently discovered in 1907 by French scientist Georges Urbain, Austrian mineralogist Baron Carl Auer von Welsbach, and American chemist Charles James. All of these researchers found lutetium as an impurity in ytterbium. The dispute on the priority of the discovery occurred shortly after, with Urbain and Welsbach accusing each other of publishing results influenced by the published research of the other; the naming honor went to Urbain, as he had published his results earlier. He chose the name ''lutecium'' for the new element, but in 1949 the spelling was changed to ''lutetium''. In 1909, the priority was ...
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Lutetium (177Lu) Oxodotreotide
Lutetium (177Lu) oxodotreotide (International Nonproprietary Name, INN) or 177Lu dotatate, brand name Lutathera, is a chelator, chelated complex of a radioisotope of the Chemical element, element lutetium with dotatate, used in peptide receptor radionuclide therapy. Specifically, it is used in the treatment of cancers which express somatostatin receptors. It is a radiolabeled somatostatin analog. Alternatives to 177Lu-dotatate include yttrium-90 dotatate or DOTATOC. The longer range of the beta particles emitted by 90Y, which deliver the therapeutic effect, may make it more suitable for large tumors with 177Lu reserved for smaller volumes The US Food and Drug Administration (FDA) considers 177Lu dotatate to be a first-in-class medication. Medical uses In the US, 177Lu dotatate is indicated for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs), including foregut, midgut, and hindgut neuroendocrine tumors in adults. In th ...
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Lanthanide
The lanthanide () or lanthanoid () series of chemical elements comprises at least the 14 metallic chemical elements with atomic numbers 57–70, from lanthanum through ytterbium. In the periodic table, they fill the 4f orbitals. Lutetium (element 71) is also sometimes considered a lanthanide, despite being a d-block element and a transition metal. The informal chemical symbol Ln is used in general discussions of lanthanide chemistry to refer to any lanthanide. All but one of the lanthanides are f-block elements, corresponding to the filling of the 4f electron shell. Lutetium is a d-block element (thus also a transition metal), and on this basis its inclusion has been questioned; however, like its congeners scandium and yttrium in group 3, it behaves similarly to the other 14. The term rare-earth element or rare-earth metal is often used to include the stable group 3 elements Sc, Y, and Lu in addition to the 4f elements. All lanthanide elements form trivalent cations, Ln3+, ...
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Ytterbium
Ytterbium is a chemical element; it has symbol Yb and atomic number 70. It is a metal, the fourteenth and penultimate element in the lanthanide series, which is the basis of the relative stability of its +2 oxidation state. Like the other lanthanides, its most common oxidation state is +3, as in its oxide, halides, and other compounds. In aqueous solution, like compounds of other late lanthanides, soluble ytterbium compounds form complexes with nine water molecules. Because of its closed-shell electron configuration, its density, melting point and boiling point are much lower than those of most other lanthanides. In 1878, Swiss chemist Jean Charles Galissard de Marignac separated from the rare earth "erbia", another independent component, which he called " ytterbia", for Ytterby, the village in Sweden near where he found the new component of erbium. He suspected that ytterbia was a compound of a new element that he called "ytterbium". Four elements were named after the village, the ...
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Lanthanide Contraction
The lanthanide contraction is the greater-than-expected decrease in atomic radii and ionic radii of the elements in the lanthanide series, from left to right. It is caused by the poor shielding effect of nuclear charge by the 4f electrons along with the expected periodic trend of increasing electronegativity and nuclear charge on moving from left to right. About 10% of the lanthanide contraction has been attributed to relativistic effects. A decrease in atomic radii can be observed across the 4f elements from atomic number 57, lanthanum, to 70, ytterbium. This results in smaller than otherwise expected atomic radii and ionic radii for the subsequent d-block elements starting with 71, lutetium. Jolly, William L. ''Modern Inorganic Chemistry'', McGraw-Hill 1984, p. 22 This effect causes the radii of transition metals of group 5 and 6 to become unusually similar, as the expected increase in radius going down a period is nearly cancelled out by the f-block insertion, and has ...
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Lutetium(III) Oxide
Lutetium(III) oxide, a white solid, is a cubic compound of lutetium sometimes used in the preparation of specialty glasses. It is also called lutecia. It is a lanthanide oxide, also known as a rare earth.Lutetium Oxide. 1997-2007. Metall Rare Earth Limited. http://www.metall.com.cn/luo.htm History In 1879, Swiss chemist Jean Charles Galissard de Marignac (1817–1894) claimed to have discovered ytterbium, but he had found a mixture of elements. In 1907, French chemist Georges Urbain (1872–1938) reported that ytterbium was a mixture of two new elements and was not a single element. Two other chemists, Carl Auer von Welsbach (1858–1929) and Charles James (1880–1926) also extracted lutetium(III) oxide around the same time. All three scientists successfully separated Marignac's ytterbia into oxides of two elements which were eventually named ytterbium and lutetium Lutetium is a chemical element; it has symbol Lu and atomic number 71. It is a silvery white metal, which resists c ...
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Georges Urbain
Georges Urbain (12 April 1872 – 5 November 1938) was a French chemist, a professor of the Sorbonne, a member of the Institut de France, and director of the Institute of Chemistry in Paris. Much of his work focused on the rare earths, isolating and separating elements such as europium and gadolinium, and studying their spectra, their magnetic properties and their atomic masses. He discovered the element lutetium (atomic number 71). He also studied the efflorescence of saline hydrates. Education After attending the Lycée Charlemagne and Lycée Lavoisier, Urbain studied at the École supérieure de physique et de chimie industrielles de la ville de Paris (ESPCI ParisTech). He graduated as the top student in the school's ninth graduating class, in 1894. At that time he also earned his '' licence ès sciences physique et chimie'' at the Sorbonne. Urbain served in teaching positions at the Préparateur at the École de Physique et Chimie Industrielle (1894-1895), i ...
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Carl Auer Von Welsbach
Carl Auer von Welsbach (1 September 1858 – 4 August 1929), who received the Austrian noble title of Freiherr Auer von Welsbach in 1901, was an Austrian scientist and inventor, who separated didymium into the elements neodymium and praseodymium in 1885. He was also one of three scientists to independently discover the element lutetium (which he named ''cassiopeium''), separating it from ytterbium in 1907, setting off the longest priority dispute in the history of chemistry. He had a talent not only for making scientific advances, but also for turning them into commercially successful products. His work on rare-earth elements led to the development of the ferrocerium "flints" used in modern lighters, the gas mantle that brought light to the streets of Europe in the late 19th century, and the metal-filament light bulb. He took the phrase ''plus lucis'', meaning "more light", as his motto. Early life Carl Auer was born in Vienna on 1 September 1858 to Alois Auer and his wife ...
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Transition Metal
In chemistry, a transition metal (or transition element) is a chemical element in the d-block of the periodic table (groups 3 to 12), though the elements of group 12 (and less often group 3) are sometimes excluded. The lanthanide and actinide elements (the f-block) are called inner transition metals and are sometimes considered to be transition metals as well. They are lustrous metals with good electrical and thermal conductivity. Most (with the exception of group 11 and group 12) are hard and strong, and have high melting and boiling temperatures. They form compounds in any of two or more different oxidation states and bind to a variety of ligands to form coordination complexes that are often coloured. They form many useful alloys and are often employed as catalysts in elemental form or in compounds such as coordination complexes and oxides. Most are strongly paramagnetic because of their unpaired d electrons, as are many of their compounds. All of the elements that are ...
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Charles James (chemist)
Charles James (27 April 1880 – 10 December 1928) was a chemist of British origin working in the United States. He became a professor and head of the chemistry department at the New Hampshire College of Agriculture and the Mechanic Arts (now the University of New Hampshire) in Durham, New Hampshire, US. James developed the James method for the separation and identification of rare-earth elements by fractional precipitation and crystallization, and provided extracted elements to researchers worldwide. James was one of the first scientists to identify element 71, later named lutetium, and believed that he had found the final rare earth element 61, later named promethium. In 1999 the American Chemical Society recognized Charles James's work in chemical separations as a National Historic Chemical Landmark. Early life Charles James was born on 27 April 1880 to William James and Mary Diana Shatford-James in Earls Barton near Wellingborough, Northamptonshire . His father died whe ...
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Chemical Element
A chemical element is a chemical substance whose atoms all have the same number of protons. The number of protons is called the atomic number of that element. For example, oxygen has an atomic number of 8: each oxygen atom has 8 protons in its atomic nucleus, nucleus. Atoms of the same element can have different numbers of neutrons in their nuclei, known as isotopes of the element. Two or more atoms can combine to form molecules. Some elements form Homonuclear molecule, molecules of atoms of said element only: e.g. atoms of hydrogen (H) form Diatomic molecule, diatomic molecules (H). Chemical compounds are substances made of atoms of different elements; they can have molecular or non-molecular structure. Mixtures are materials containing different chemical substances; that means (in case of molecular substances) that they contain different types of molecules. Atoms of one element can be transformed into atoms of a different element in nuclear reactions, which change an atom's at ...
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Rare Earth Element
The rare-earth elements (REE), also called the rare-earth metals or rare earths, and sometimes the lanthanides or lanthanoids (although scandium and yttrium, which do not belong to this series, are usually included as rare earths), are a set of 17 nearly indistinguishable lustrous silvery-white soft heavy metals. Compounds containing rare earths have diverse applications in electrical and electronic components, lasers, glass, magnetic materials, and industrial processes. The term "rare-earth" is a misnomer because they are not actually scarce, but historically it took a long time to isolate these elements. They are relatively plentiful in the entire Earth's crust ( cerium being the 25th-most-abundant element at 68 parts per million, more abundant than copper), but in practice they are spread thinly as trace impurities, so to obtain rare earths at usable purity requires processing enormous amounts of raw ore at great expense; thus the name "rare" earths. Scandium and yttrium a ...
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Atomic Number
The atomic number or nuclear charge number (symbol ''Z'') of a chemical element is the charge number of its atomic nucleus. For ordinary nuclei composed of protons and neutrons, this is equal to the proton number (''n''p) or the number of protons found in the nucleus of every atom of that element. The atomic number can be used to uniquely identify ordinary chemical elements. In an ordinary uncharged atom, the atomic number is also equal to the number of electrons. For an ordinary atom which contains protons, neutrons and electrons, the sum of the atomic number ''Z'' and the neutron number ''N'' gives the atom's atomic mass number ''A''. Since protons and neutrons have approximately the same mass (and the mass of the electrons is negligible for many purposes) and the mass defect of the nucleon binding is always small compared to the nucleon mass, the atomic mass of any atom, when expressed in daltons (making a quantity called the " relative isotopic mass"), is within 1% ...
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