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Lewy Body Dementia
Lewy body dementia (LBD) is an umbrella term for two similar and common subtypes of dementia: dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). Both are characterized by changes in thinking, movement, behavior, and mood. The two conditions have similar features and may have similar causes, and are believed to belong on a spectrum of Lewy body disease that includes Parkinson's disease. As of 2014, they were more often misdiagnosed than any other common dementia. The exact cause is unknown, but involves widespread deposits of abnormal clumps of protein that form in neurons of the diseased brain. Known as Lewy bodies (discovered in 1912 by Frederic Lewy) and Lewy neurites, these clumps affect both the central nervous system and the autonomic nervous system. The fifth revision of the ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM-5) gives Lewy body disease as the causative subtype of dementia with Lewy bodies, and Parkinson's disease as the ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dementia
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform activities of daily living, everyday activities. This typically involves problems with memory, thinking, behavior, and motor control. Aside from memory impairment and a thought disorder, disruption in thought patterns, the most common symptoms of dementia include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum (measurement), continuum over several stages. Dementia is a life-limiting condition, having a significant effect on the individual, their caregivers, and their social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning and a greater cognitive decline than might be caused by the normal aging process. Several diseases and injuries to the brain, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visual Hallucination
A visual hallucination is a vivid visual experience occurring without corresponding external stimuli in an awake state. These experiences are involuntary and possess a degree of perceived reality sufficient to resemble authentic visual perception. Unlike illusions, which involve the misinterpretation of actual external stimuli, visual hallucinations are entirely independent of external visual input. They may include fully formed images, such as human figures or scenes, angelic figures, or unformed phenomena, like flashes of light or geometric patterns. Visual hallucinations are not restricted to the transitional states of awakening or falling asleep and are a hallmark of various neurological and psychiatric conditions. They are documented in schizophrenia, toxic encephalopathies, migraines, substance withdrawal syndromes, focal central nervous system lesions, and psychotic mood disorders. Although traditionally linked with organic aetiologies, visual hallucinations occur in approx ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paranoia
Paranoia is an instinct or thought process that is believed to be heavily influenced by anxiety, suspicion, or fear, often to the point of delusion and irrationality. Paranoid thinking typically includes persecutory beliefs, or beliefs of conspiracy concerning a perceived threat towards oneself (e.g., ''"Everyone is out to get me"''). Paranoia is distinct from phobias, which also involve irrational fear, but usually no blame. Making false accusations and the general distrust of other people also frequently accompany paranoia. For example, a paranoid person might believe an incident was intentional when most people would view it as an accident or coincidence. Paranoia is a central symptom of psychosis.Green, C., Freeman, D., Kuipers, E., Bebbington, P., Fowler, D., Dunn, G., & Garety, P. (2008). Measuring ideas of persecution and social reference: the Green et al. Paranoid Thought Scales (GPTS). ''Psychological Medicine, 38'', 101 – 111. Signs and symptoms A common symptom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anxiety
Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response to a present threat, whereas anxiety is the anticipation of a future one. It is often accompanied by nervous behavior such as pacing back and forth, Somatic anxiety, somatic complaints, and Rumination (psychology), rumination. Anxiety is a feeling of uneasiness and worry, usually generalized and unfocused as an overreaction to a situation that is only subjectively seen as menacing. It is often accompanied by muscular tension, restlessness, Fatigue (medical), fatigue, inability to catch one's breath, tightness in the abdominal region, nausea, and problems in concentration. Anxiety is closely related to fear, which is a response to a real or perceived immediate threat (fight-or-flight response); anxiety involves the expectation of a future t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robin Williams
Robin McLaurin Williams (July 21, 1951August 11, 2014) was an American actor and comedian known for his improvisational skills and the wide variety of characters he created on the spur of the moment and portrayed on film, in dramas and comedies alike, Williams is regarded as one of the greatest comedians of all time. He received numerous accolades including an Academy Award, two Primetime Emmy Awards, six Golden Globe Awards, five Grammy Awards, and two Screen Actors Guild Awards. Williams was awarded the Cecil B. DeMille Award in 2005. Born in Chicago, Williams began performing stand-up comedy in San Francisco and Los Angeles during the mid-1970s, and released several comedy albums including ''Reality ... What a Concept'' in 1980. He rose to fame playing the alien Mork in the ABC sitcom ''Mork & Mindy'' (1978–1982). Williams received his first leading film role in ''Popeye'' (1980). Williams won the Academy Award for Best Supporting Actor for '' Good Will Hunting'' (1997 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robin Williams 2011a
Robin most commonly refers to several species of passerine birds. Robin may also refer to: Animals * Australasian robins, red-breasted songbirds of the family Petroicidae * Many members of the subfamily Saxicolinae (Old World chats), including: **European robin (''Erithacus rubecula'') ** Bush-robin **Forest robin **Magpie-robin **Scrub robin **Robin-chat ** Bagobo robin **White-starred robin **White-throated robin ** Blue-fronted robin **Larvivora (6 species) **Myiomela (3 species) * Some red-breasted New-World true thrushes (''Turdus'') of the family Turdidae, including: ** American robin (''T. migratorius'') (so named by 1703) ** Rufous-backed thrush (''T. rufopalliatus'') ** Rufous-collared thrush (''T. rufitorques'') ** Formerly other American thrushes, such as the clay-colored thrush (''T. grayi'') * Pekin robin or Japanese (hill) robin, archaic names for the red-billed leiothrix (''Leiothrix lutea''), red-breasted songbirds * Sea robin, a fish with small "legs" (ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lewy Body Society
Lewy may refer to: * Lewy (surname) * Levi, a biblical personage * Lewy body, abnormal aggregates of protein that develop inside nerve cells of the brain * Dementia with Lewy bodies, progressive brain disease associated with degenerative dementia in the elderly * A nickname for Polish footballer Robert Lewandowski Robert Lewandowski (; born 21 August 1988) is a Polish professional Association football, footballer who plays as a Striker (association football), striker for club FC Barcelona, Barcelona. Widely regarded as one of the greatest strikers of a ... (born 1988) See also * {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lewy Body Dementia Association
The Lewy Body Dementia Association (LBDA) is a US nonprofit organization based in Lilburn, Georgia, and "dedicated to raising awareness of the Lewy body dementias (LBD), supporting people with LBD, their families and caregivers and promoting scientific advances". Through "outreach, education and research", their mission is to support people affected by LBD. Work According to a 2014 review, the LBDA provides services that aid society and families with LBD. They provide support and awareness, reduce stress on individuals and families with LBD, and may reduce use of healthcare. They help enable better diagnoses and better understanding of LBD. A 2013 journal review of treatment of dementia with Lewy bodies suggests that caregivers join support groups including the LBDA for helpful information. In 2018, the LBDA launched a collaboration of 24 US Research Centers of Excellence, coordinated by Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antipsychotic
Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of Psychiatric medication, psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. They are also the mainstay, together with mood stabilizers, in the treatment of bipolar disorder. Moreover, they are also used as adjuncts in the treatment of Treatment-resistant depression, treatment-resistant major depressive disorder. The use of antipsychotics may result in many unwanted side effects such as Extrapyramidal symptoms, involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce List of long term side effects of antipsychotics, adverse effects such as tardive dyskinesia, tardive dystonia, Akathisia, tardive akathisia, and brain tissue volume reduction. The long term use of antipsychotics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caregiver
A caregiver, carer or support worker is a paid or unpaid person who helps an individual with activities of daily living. Caregivers who are members of a care recipient's family or social network, who may have specific professional training, are often described as informal caregivers. Caregivers most commonly assist with impairments related to old age, disability, a disease, or a mental disorder. Typical duties of a caregiver might include taking care of someone who has a chronic illness or disease; managing medications or talking to doctors and nurses on someone's behalf; helping to bathe or dress someone who is frail or disabled; or taking care of household chores, meals, or processes both formal and informal documentations related to health for someone who cannot do these things alone. With an aging population in all developed societies, the role of caregivers has been increasingly recognized as an important one, both functionally and economically. Many organizations that provi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. The causes of Alzheimer's disease remain poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression, and high blood pressure. The progression of the di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Misfolded Protein
Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random coil into a more ordered three-dimensional structure. This structure permits the protein to become biologically functional or active. The folding of many proteins begins even during the translation of the polypeptide chain. The amino acids interact with each other to produce a well-defined three-dimensional structure, known as the protein's native state. This structure is determined by the amino-acid sequence or primary structure. The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, indicating that protein dynamics are important. Failure to fold into a native structure generally produces inactive proteins, but in some instances, misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
