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Kathleen I. Pritchard
Kathleen I. Pritchard, is the head of oncology at Sunnybrook Health Sciences Centre in Toronto, Canada, specializing in breast cancer therapies, and leading the clinical trials division of the centre. She has authored numerous studies on women's health, breast cancer, hormone replacement therapy, public health, and research methodology. According to Thomson Reuters, Pritchard was one of the most cited researchers in the world in 2014 and 2015. Biography Kathleen I. Pritchard, CM, grew up in Deep River, Ontario. She graduated from the local high school in 1964. She earned her Bachelor's in Science in 1968 from Queen's University in Kingston, Ontario and attained her medical degree there in 1971. Her practicum in Internal Medicine was completed at Wellesley Hospital, Toronto Western Hospital, and Toronto General Hospital. Between 1973 and 1974 at the University of Toronto, Pritchard focused on research into melanoma and tumor immunology, and then in 1977 began researching breas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brackets
A bracket is either of two tall fore- or back-facing punctuation marks commonly used to isolate a segment of text or data from its surroundings. Typically deployed in symmetric pairs, an individual bracket may be identified as a 'left' or 'right' bracket or, alternatively, an "opening bracket" or "closing bracket", respectively, depending on the Writing system#Directionality, directionality of the context. Specific forms of the mark include parentheses (also called "rounded brackets"), square brackets, curly brackets (also called 'braces'), and angle brackets (also called 'chevrons'), as well as various less common pairs of symbols. As well as signifying the overall class of punctuation, the word "bracket" is commonly used to refer to a specific form of bracket, which varies from region to region. In most English-speaking countries, an unqualified word "bracket" refers to the parenthesis (round bracket); in the United States, the square bracket. Glossary of mathematical sym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toronto Western Hospital
The Toronto Western Hospital (TWH) is a major research and teaching hospital in Toronto, Ontario, Canada. It is part of the University Health Network (UHN). It has 256 beds, with 46,000 visits to its emergency department annually. It is known for neurosurgery and was one of the first centres in Canada to use the gamma knife. It is also home to the Donald K. Johnson Eye Centre and the Krembil Discovery Tower where the Krembil Research Institute is based. History In 1895, doctors serving what was then the west end of Toronto united in hopes of building a full hospital facility to serve this overlooked locale. Twelve doctors signed a pledge to fulfill their vision and soon after, the Toronto Western Hospital was born. The Toronto Western Hospital opened first as a public dispensary, followed by a 30-bed hospital operating out of two rented houses on Manning Avenue. With the support of several influential citizens, enough money was raised by 1899 to acquire a nearby farmhouse proper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Clinical Oncology
The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by the Lippincott Williams & Wilkins. It covers research on all aspects of clinical oncology. The journal was established in 1983 and the editor-in-chief is Jonathan W. Friedberg (University of Rochester). JCO's Impact Factor is 44.544 as reported by Clarivate in its 2020 Journal Citation Reports. History In 1981 Emil Frei III proposed that the American Society of Clinical Oncology should publish an official journal and that it should be called ''Journal of Clinical Oncology''. The first issue was published on January 1, 1983, containing 70 pages of research and an editorial by the then editor-in-chief, Joseph Bertino. Bertino was succeeded by George P. Canellos in 1987. In 1998, a Spanish language edition of the journal started quarterly publication, followed by a Chinese language edition. Currently there are 10 international editions. Daniel Haller became editor-in-chief in 200 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of The National Cancer Institute
The ''Journal of the National Cancer Institute'' (''JNCI'') is a peer-reviewed medical journal covering research in oncology that was established in August 1940. It is published monthly by Oxford University Press and is edited by Patricia A. Ganz. It was merged with ''Cancer Treatment Reports'' in January 1988. ''JNCI'' used to be the official journal of the National Cancer Institute (NCI); however, in 1996, the NCI and ''JNCI'' agreed to grow apart. Over the next five years, ''JNCI'' became independent of the NCI. A related publication is ''Journal of the National Cancer Institute Monographs'' (''JNCI Monographs''), established in 1959, which publishes manuscripts from cancer and cancer-related conferences, as well as groups of papers on specific subjects related to cancer. In January 1986, ''Cancer Treatment Symposia'' was merged with ''JNCI Monographs''. Additionally, ''JNCI Cancer Spectrum'' (''JNCI CS'') is a fully open access journal, which was established in 2017. It is pub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. History In September 1811, John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' purchased the weekly ''Intelligencer'' for $600 in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Relapse
In internal medicine, relapse or recidivism is a recurrence of a past (typically medical) condition. For example, multiple sclerosis and malaria often exhibit peaks of activity and sometimes very long periods of dormancy, followed by relapse or recrudescence. In psychiatry, relapse or reinstatement of drug-seeking behavior, is the recurrence of pathological drug use, self harm or other symptoms after a period of recovery. Relapse is often observed in individuals who have developed a drug addiction or a form of drug dependence, as well as those who have a mental disorder. Risk factors Dopamine D2 receptor availability The availability of the dopamine receptor D2 plays a role in self-administration and the reinforcing effects of cocaine and other stimulants. The D2 receptor availability has an inverse relationship to the vulnerability of reinforcing effects of the drug. With the D2 receptors becoming limited, the user becomes more susceptible to the reinforcing effects of coca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Menopause
Menopause, also known as the climacteric, is the time in women's lives when menstrual periods stop permanently, and they are no longer able to bear children. Menopause usually occurs between the age of 47 and 54. Medical professionals often define menopause as having occurred when a woman has not had any menstrual bleeding for a year. It may also be defined by a decrease in hormone production by the ovaries. In those who have had surgery to remove their uterus but still have functioning ovaries, menopause is not considered to have yet occurred. Following the removal of the uterus, symptoms typically occur earlier. In the years before menopause, a woman's periods typically become irregular, which means that periods may be longer or shorter in duration or be lighter or heavier in the amount of flow. During this time, women often experience hot flashes; these typically last from 30 seconds to ten minutes and may be associated with shivering, sweating, and reddening of the skin. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormonal Therapy (oncology)
Hormonal therapy in oncology is hormone therapy for cancer and is one of the major modalities of medical oncology (pharmacotherapy for cancer), others being cytotoxic chemotherapy and targeted therapy (biotherapeutics). It involves the manipulation of the endocrine system through exogenous or external administration of specific hormones, particularly steroid hormones, or drugs which inhibit the production or activity of such hormones (hormone antagonists). Because steroid hormones are powerful drivers of gene expression in certain cancer cells, changing the levels or activity of certain hormones can cause certain cancers to cease growing, or even undergo cell death. Surgical removal of endocrine organs, such as orchiectomy and oophorectomy can also be employed as a form of hormonal therapy. Hormonal therapy is used for several types of cancers derived from hormonally responsive tissues, including the breast, prostate, endometrium, and adrenal cortex. Hormonal therapy may als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Odette Cancer Centre
Sunnybrook Health Sciences Centre (SHSC), commonly known as Sunnybrook Hospital or simply Sunnybrook, is an academic health science centre located in Toronto, Ontario, Canada. It is the largest trauma centre in Canada and one of two trauma centres in Toronto, the other being St. Michael's Hospital. Sunnybrook is a teaching hospital fully affiliated with the University of Toronto. The hospital is home to Canada's largest veterans centre, in the Kilgour Wing and the George Hees, which cares for World War II and Korean War veterans. Sunnybrook has made surgical breakthroughs in its history, including the world's first non-invasive opening of the blood–brain barrier being performed in 2015. History Sunnybrook Hospital had its origins as the Toronto Military Orthopaedic Hospital at 350 Christie Street, which was also known as the Christie Street Military Hospital and, after 1936, the Christie Street Veterans' Hospital. The Collegiate Gothic building had originally been the site of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canadian Cancer Society
The Canadian Cancer Society (french: Société canadienne du cancer) is Canada's largest national cancer charity and the largest national charitable funder of cancer research in Canada. History The idea to form the Canadian Cancer Society originally came from the Saskatchewan Medical Association in 1929, when they formed Canada's first cancer committee. In 1937, the National Study Committee recommended the formation of new organization, which was later called Canadian Cancer Society for the Control of Cancer. The Canadian Cancer Society (CCS) was officially formed a decade later, in 1938, to educate Canadians about the early warning signs of cancer. At that time, many people did not seek medical help until their cancer had advanced past a treatable stage. In 1947, CCS began funding cancer research through the creation of the National Cancer Institute of Canada, an agreement between the Canadian Cancer Society and the Federal Department of Health and Welfare. The Society continu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Women's College Hospital
Women's College Hospital is a teaching hospital in downtown Toronto, Ontario, Canada. It is located at the north end of Hospital Row, a section of University Avenue where several major hospitals are located. It currently functions as an independent ambulatory care hospital. The Chief of Staff is Dr. Sheila Laredo and the physician-in-chief is Dr. Paula Harvey. Women's College Hospital maintains a focus on women's health, research in women's health, and ambulatory care. It was recognized as the only ''collaborating centre'' in women's health the Western Hemisphere designated by the World Health Organization. Women's College Hospital is associated with Women's College Research Institute, Women's College Hospital Foundation and Women's Health Matters, a bilingual consumer website on women's health and lifestyle issues. History Women's College Hospital began as Woman's Medical College in 1883. On June 13, 1883, Dr. Emily Stowe (1831–1903) the second woman licensed to practice medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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