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KC (patient)
Kent Cochrane (August 5, 1951 – March 27, 2014), also known as Patient K.C., was a widely studied Canadian memory disorder patient who has been used as a case study in over 20 neuropsychology papers over the span of 25 years. In 1981, Cochrane was involved in a motorcycle accident that left him with severe anterograde amnesia, as well as temporally graded retrograde amnesia. Like other amnesic patients (patient HM, for example), Cochrane had his semantic memory intact, but lacked episodic memory with respect to his entire past. As a case study, Cochrane has been linked to the breakdown of the single-memory single-locus hypothesis regarding amnesia, which states that an individual memory is localized to a single location in the brain. Early life Kent Cochrane was born on August 5, 1951, as the oldest of five children. They grew up in the suburbs of Toronto, Ontario. After attending a community college to study business administration, he obtained a quality control job at a man ...
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Toronto
Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a population of 2,794,356 in 2021, it is the List of North American cities by population, fourth-most populous city in North America. The city is the anchor of the Golden Horseshoe, an urban agglomeration of 9,765,188 people (as of 2021) surrounding the western end of Lake Ontario, while the Greater Toronto Area proper had a 2021 population of 6,712,341. As of 2024, the census metropolitan area had an estimated population of 7,106,379. Toronto is an international centre of business, finance, arts, sports, and culture, and is recognized as one of the most multiculturalism, multicultural and cosmopolitanism, cosmopolitan cities in the world. Indigenous peoples in Canada, Indigenous peoples have travelled through and inhabited the Toronto area, ...
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Sulcus (neuroanatomy)
In neuroanatomy, a sulcus (Latin: "furrow"; : sulci) is a shallow Sulcus (morphology), depression or groove in the cerebral cortex. One or more sulci surround a gyrus (pl. gyri), a ridge on the surface of the cortex, creating the characteristic folded appearance of the brain in humans and most other mammals. The larger sulci are also called Sulcus (morphology)#Brain, fissures. The cortex develops in the fetal stage of corticogenesis, preceding the cortical folding stage known as gyrification. The large fissures and main sulci are the first to develop. Mammals that have a folded cortex are known as ''gyrencephalic'', and the small-brained mammals that have a smooth cortex, such as rats and mice are termed lissencephaly, lissencephalic. Structure Sulci, the grooves, and gyri, the folds or ridges, make up the gyrification, folded surface of the cerebral cortex. Larger or deeper sulci are also often termed fissures. The folded cortex creates a larger surface area for the brain in h ...
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Priming (psychology)
Priming is a concept in psychology and psycholinguistics to describe how exposure to one stimulus may influence a response to a subsequent stimulus, without conscious guidance or intention. The priming effect is the positive or negative effect of a rapidly presented stimulus (priming stimulus) on the processing of a second stimulus (target stimulus) that appears shortly after. Generally speaking, the generation of priming effect depends on the existence of some positive or negative relationship between priming and target stimuli. For example, the word ''nurse'' might be recognized more quickly following the word ''doctor'' than following the word ''bread''. Priming can be perceptual, associative, repetitive, positive, negative, affective, semantic, or conceptual. Priming effects involve word recognition, semantic processing, attention, unconscious processing, and many other issues, and are related to differences in various writing systems. How quickly this effect occurs is conte ...
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Hippocampus
The hippocampus (: hippocampi; via Latin from Ancient Greek, Greek , 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system. The hippocampus plays important roles in the Memory consolidation, consolidation of information from short-term memory to long-term memory, and in spatial memory that enables Navigation#Navigation in spatial cognition, navigation. In humans, and other primates the hippocampus is located in the archicortex, one of the three regions of allocortex, in each cerebral hemisphere, hemisphere with direct neural projections to, and reciprocal indirect projections from the neocortex. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of th ...
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Autopsy
An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death; or the exam may be performed to evaluate any disease or injury that may be present for research or educational purposes. The term ''necropsy'' is generally used for non-human animals. Autopsies are usually performed by a specialized medical doctor called a pathologist. Only a small portion of deaths require an autopsy to be performed, under certain circumstances. In most cases, a medical examiner or coroner can determine the cause of death. Purposes of performance Autopsies are performed for either legal or medical purposes. Autopsies can be performed when any of the following information is desired: * Manner of death must be determined ** Determine if death was natural or unnatural ** Injury source and extent on the corpse * Pos ...
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Stroke
Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of stroke may include an hemiplegia, inability to move or feel on one side of the body, receptive aphasia, problems understanding or expressive aphasia, speaking, dizziness, or homonymous hemianopsia, loss of vision to one side. Signs and symptoms often appear soon after the stroke has occurred. If symptoms last less than 24 hours, the stroke is a transient ischemic attack (TIA), also called a mini-stroke. subarachnoid hemorrhage, Hemorrhagic stroke may also be associated with a thunderclap headache, severe headache. The symptoms of stroke can be permanent. Long-term complications may include pneumonia and Urinary incontinence, loss of b ...
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Heart Attack
A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom is retrosternal Angina, chest pain or discomfort that classically radiates to the left shoulder, arm, or jaw. The pain may occasionally feel like heartburn. This is the dangerous type of acute coronary syndrome. Other symptoms may include shortness of breath, nausea, presyncope, feeling faint, a diaphoresis, cold sweat, Fatigue, feeling tired, and decreased level of consciousness. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an Cardiac arrhythmia, irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur d ...
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Autonoetic Consciousness
Autonoetic consciousness is the human ability to mentally place oneself in the past and future (i.e. mental time travel) or in counterfactual situations (i.e. alternative outcomes), and to thus be able to examine one's own thoughts. One's sense of self affects their behavior, in the present, past and future. It relates to how one reflects on their own past behavior, how they feel about it, and this in turn determines if they do it again. It is episodic memory that deals with self-awareness, memories of the self and inward thoughts that may be projected onto future actions of an individual. It was "proposed by Endel Tulving for self-awareness, allowing the rememberer to reflect on the contents of episodic memory". Moreover, autonoetic consciousness involves behaviors such as mental time travel, self-projection, and episodic future thinking, all of which have often been proposed as exclusively human capacities. The self Autonoetic consciousness is important in our formation of ...
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Noetic Consciousness
Phenomenology is a philosophical study and movement largely associated with the early 20th century that seeks to objectively investigate the nature of subjective, conscious experience. It attempts to describe the universal features of consciousness while avoiding assumptions about the external world, aiming to describe phenomena as they appear, and to explore the meaning and significance of lived experience. This approach, while philosophical, has found many applications in qualitative research across different scientific disciplines, especially in the social sciences, humanities, psychology, and cognitive science, but also in fields as diverse as health sciences, architecture, and human-computer interaction, among many others. The application of phenomenology in these fields aims to gain a deeper understanding of subjective experience, rather than focusing on behavior. Phenomenology is contrasted with phenomenalism, which reduces mental states and physical objects to comple ...
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Hippocampal
The hippocampus (: hippocampi; via Latin from Greek , 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system. The hippocampus plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. In humans, and other primates the hippocampus is located in the archicortex, one of the three regions of allocortex, in each hemisphere with direct neural projections to, and reciprocal indirect projections from the neocortex. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to be damaged; short-term memory loss and disorientation are included among the e ...
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Temporal Lobes
The temporal lobe is one of the four Lobes of the brain, major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's Temple (anatomy), temples. Structure The Temple (anatomy)#Etymology, temporal Lobe (anatomy), lobe consists of structures that are vital for declarative or long-term memory. Declarative memory, Declarative (denotative) or Explicit memory, explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). The medial temporal lobe structures are critical for long-term memory, and include the hippocampal formation, perirhinal cortex, Parahippocampal gyrus, parahippocampal, and Entorhinal cortex, entorhinal neoco ...
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