John Stanley Griffith
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John Stanley Griffith
John Stanley Griffith (1928–1972) was a British chemist, mathematician and biophysicist. He was the nephew of the distinguished British bacteriologist Frederick Griffith. Career Beginning as an undergraduate in mathematics at Trinity College, Cambridge in 1946–1949, he went on to read Part II biochemistry in 1949–1951. His research career continued in theoretical chemistry at Oxford and Cambridge, where he held a Berry-Ramsey research fellowship at King's College. He had several appointments in Britain and the US in his different disciplines. These included professorships in chemistry at Indiana University Bloomington and at the University of Pennsylvania, where he received the Marlow Award of the Royal Society of Chemistry in 1961. He then spent time at the Department of Mathematics at UMIST in Manchester. In 1967 he was appointed to a chair in the Department of Mathematics of Bedford College, London, where his inaugural lecture was entitled "The Neural Basis of Conscious ...
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Biophysicist
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. ...
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Inorganic Chemistry
Inorganic chemistry deals with synthesis and behavior of inorganic and organometallic compounds. This field covers chemical compounds that are not carbon-based, which are the subjects of organic chemistry. The distinction between the two disciplines is far from absolute, as there is much overlap in the subdiscipline of organometallic chemistry. It has applications in every aspect of the chemical industry, including catalysis, materials science, pigments, surfactants, coatings, medications, fuels, and agriculture. Key concepts Many inorganic compounds are ionic compounds, consisting of cations and anions joined by ionic bonding. Examples of salts (which are ionic compounds) are magnesium chloride MgCl2, which consists of magnesium cations Mg2+ and chloride anions Cl−; or sodium oxide Na2O, which consists of sodium cations Na+ and oxide anions O2−. In any salt, the proportions of the ions are such that the electric charges cancel out, so that the bulk compound is ele ...
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1972 Deaths
Year 197 ( CXCVII) was a common year starting on Saturday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Magius and Rufinus (or, less frequently, year 950 ''Ab urbe condita''). The denomination 197 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * February 19 – Battle of Lugdunum: Emperor Septimius Severus defeats the self-proclaimed emperor Clodius Albinus at Lugdunum (modern Lyon). Albinus commits suicide; legionaries sack the town. * Septimius Severus returns to Rome and has about 30 of Albinus's supporters in the Senate executed. After his victory he declares himself the adopted son of the late Marcus Aurelius. * Septimius Severus forms new naval units, manning all the triremes in Italy with heavily armed troops for war in the East. His soldiers embar ...
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1928 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album '' 63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipkno ...
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Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule. Crick and Watson's paper in ''Nature'' in 1953 laid the groundwork for understanding DNA structure and functions. Together with Maurice Wilkins, they were jointly awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term " central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids. In other wor ...
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Prion
Prions are misfolded proteins that have the ability to transmit their misfolded shape onto normal variants of the same protein. They characterize several fatal and transmissible neurodegenerative diseases in humans and many other animals. It is not known what causes a normal protein to misfold, but the resulting abnormal three-dimensional structure confers infectious properties by collapsing nearby protein molecules into the same shape. The word ''prion'' is derived from the term, "proteinaceous infectious particle". In comparison to all other known infectious agents such as viroids, viruses, bacteria, fungi, and parasites, all of which contain nucleic acids ( DNA, RNA, or both), the hypothesized role of a protein as an infectious agent stands in contrast. Prion isoforms of the prion protein (PrP), whose specific function is uncertain, are hypothesized as the cause of transmissible spongiform encephalopathies (TSEs), including scrapie in sheep, chronic wasting disease ( ...
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Stanley B
Stanley may refer to: Arts and entertainment Film and television * ''Stanley'' (1972 film), an American horror film * ''Stanley'' (1984 film), an Australian comedy * ''Stanley'' (1999 film), an animated short * ''Stanley'' (1956 TV series), an American situation comedy * ''Stanley'' (2001 TV series), an American animated series Other uses in arts and entertainment * ''Stanley'' (play), by Pam Gems, 1996 * Stanley Award, an Australian Cartoonists' Association award * '' Stanley: The Search for Dr. Livingston'', a video game * Stanley (Cars), a character in ''Cars Toons: Mater's Tall Tales'' * '' The Stanley Parable'', a 2011 video game developed by Galactic Cafe, and its titular character, Stanley Businesses and organisations * Stanley, Inc., American information technology company * Stanley Aviation, American aerospace company * Stanley Black & Decker, formerly The Stanley Works, American hardware manufacturer ** Stanley knife, a utility knife * Stanley bottle, a brand ...
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Transmissible Spongiform Encephalopathies
Transmissible spongiform encephalopathies (TSEs) are a group of progressive and fatal conditions that are associated with prions and affect the brain and nervous system of many animals, including humans, cattle, and sheep. According to the most widespread hypothesis, they are transmitted by prions, though some other data suggest an involvement of a ''Spiroplasma'' infection. Mental and physical abilities deteriorate and many tiny holes appear in the cortex causing it to appear like a sponge when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen chronically. TSEs of humans include Creutzfeldt–Jakob disease, Gerstmann–Sträussler–Scheinker syndrome, fatal familial insomnia, and kuru, as well as the recently discovered variably protease-sensitive prionopathy and familial spongiform encephalopathy. Creutzfeldt-Jakob disease its ...
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Tikvah Alper
Tikvah Alper (22 January 1909 – 2 February 1995) trained as a physicist and became a distinguished radiobiologist. Among many other initiatives and discoveries, she was among the first to find evidence indicating that the infectious agent in Scrapie does not contain nucleic acid: a finding that was instrumental in understanding the development of the Prion theory. She was director of the MRC Experimental Radiopathology Unit, Hammersmith Hospital, London, UK, 1962–1974. She married Max Sterne but never adopted his name. Early life and career Tikvah Alper was born in South Africa, the youngest of four daughters in a family of Jewish refugees from Russia. As a schoolgirl at Durban Girls' High School, she was described as "the most intellectually distinguished girl ever to attend the school", and matriculated with distinction a year early. She graduated with distinction in physics from University of Cape Town in 1929, and then studied in Berlin with the nuclear physicist ...
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Ligand Field Theory
Ligand field theory (LFT) describes the bonding, orbital arrangement, and other characteristics of coordination complexes. It represents an application of molecular orbital theory to transition metal complexes. A transition metal ion has nine valence atomic orbitals - consisting of five ''n''d, one (''n''+1)s, and three (''n''+1)p orbitals. These orbitals are of appropriate energy to form bonding interaction with ligands. The LFT analysis is highly dependent on the geometry of the complex, but most explanations begin by describing octahedral complexes, where six ligands coordinate to the metal. Other complexes can be described by reference to crystal field theory.G. L. Miessler and D. A. Tarr "Inorganic Chemistry" 3rd Ed, Pearson/Prentice Hall publisher, . History Ligand field theory resulted from combining the principles laid out in molecular orbital theory and crystal field theory, which describes the loss of degeneracy of metal d orbitals in transition metal complexes. John S ...
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Transition Metal
In chemistry, a transition metal (or transition element) is a chemical element in the d-block of the periodic table (groups 3 to 12), though the elements of group 12 (and less often group 3) are sometimes excluded. They are the elements that can use d orbitals as valence orbitals to form chemical bonds. The lanthanide and actinide elements (the f-block) are called inner transition metals and are sometimes considered to be transition metals as well. Since they are metals, they are lustrous and have good electrical and thermal conductivity. Most (with the exception of group 11 and group 12) are hard and strong, and have high melting and boiling temperatures. They form compounds in any of two or more different oxidation states and bind to a variety of ligands to form coordination complexes that are often coloured. They form many useful alloys and are often employed as catalysts in elemental form or in compounds such as coordination complexes and oxides. Most are strongly paramag ...
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Bedford College, London
Bedford College was in York Place after 1874 Bedford College was founded in London in 1849 as the first higher education college for women in the United Kingdom. In 1900, it became a constituent of the University of London. Having played a leading role in the advancement of women in higher education and public life in general, it became fully coeducational (i.e. open to men) in the 1960s. In 1985, Bedford College merged with Royal Holloway College, another constituent of the University of London, to form Royal Holloway and Bedford New College. This remains the official name, but it is commonly called Royal Holloway, University of London (RHUL). History Foundation The college was founded by Elizabeth Jesser Reid (''née'' Sturch) in 1849, a social reformer and anti-slavery activist, who had been left a private income by her late husband, Dr John Reid, which she used to patronise various philanthropic causes. Mrs Reid and her circle of well-educated friends believed firmly in ...
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