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James W. Black
Sir James Whyte Black (14 June 1924 – 22 March 2010) was a Scottish physician and pharmacologist. Together with Gertrude B. Elion and George H. Hitchings, he shared the Nobel Prize for Medicine in 1988 for pioneering strategies for rational drug-design, which, in his case, lead to the development of propranolol and cimetidine. Black established a Veterinary Physiology department at the University of Glasgow, where he became interested in the effects of adrenaline on the human heart. He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment of heart disease. Black was also responsible for the development of cimetidine, an H2 receptor antagonist, a drug used to treat stomach ulcers. Early life and education Black was born on 14 June 1924 in Uddingston, Lanarkshire, the fourth of five sons of a Baptist family which traced its origins to Balquhidder, Perthshire. His father was a mining engineer. He was brough ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uddingston
Uddingston ( sco, Uddinstoun, gd, Baile Udain) is a small town in South Lanarkshire, Scotland. It is on the north side of the River Clyde, south-east of Glasgow city centre, and acts as a dormitory suburb for the city. Geography and boundaries Uddingston is located to the south-east of Glasgow city centre and approximately east of the Glasgow City Council boundary (ending at the former Glasgow Zoo at Broomhouse - part of Baillieston). It is bounded to the south-west by the River Clyde as it flows north-west towards Glasgow, separating Uddingston, along with some woodland, from the neighbouring towns of Blantyre to the south and Cambuslang to the west. As such, the Clyde Walkway and National Cycle Route 75 both traverse the town. The nearest settlement to Uddingston is the large village of Bothwell, almost contiguous to the south-east; the two main streets are apart. The village of Uddingston, which is contained exclusively within the boundaries of South Lanarkshire, houses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baptist Union Of Scotland
The Baptist Union of Scotland is a Baptist Christian denomination in Scotland. It is affiliated with the Baptist World Alliance. The headquarters is in Glasgow. History From the 1650s to 1869 Baptists first arrived in Scotland with the armies of English republican Oliver Cromwell in the 1650s, who established small churches in Leith, Perth, Cupar, Ayr and Aberdeen, but they did not survive for long, partly because of their association with Cromwell (who was generally not welcomed in Scotland), but more especially as a result of strident and often violent opposition instigated and inspired by the Church of Scotland and the Parliament of Scotland which it controlled. Baptists later emerged in the 18th century—in 1750 at Keiss, where the leader was William Sinclair and the church was established on the English Baptist pattern. The group who in Edinburgh came to Baptist convictions in 1765 under the leadership of Robert Carmichael and Archibald McLean became known as Scotch Bapti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stomach Ulcers
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases. Common causes include the bacteria '' Helicobacter pylori'' and non-steroidal anti-inflammatory drugs (NSAIDs). Other, less common causes include tobacco smoking, stress as a result of other serious health conditions, Behçet's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beta Blocker
Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack after a first heart attack ( secondary prevention). They are also widely used to treat high blood pressure, although they are no longer the first choice for initial treatment of most patients. Beta blockers are competitive antagonists that block the receptor sites for the endogenous catecholamines epinephrine (adrenaline) and norepinephrine (noradrenaline) on adrenergic beta receptors, of the sympathetic nervous system, which mediates the fight-or-flight response. Some block activation of all types of β-adrenergic receptors and others are selective for one of the three known types of beta receptors, designated β1, β2 and β3 receptors. β1-adrenergic receptors are located mainly in the heart and in the kidneys. β2-adrenergic receptors are located mainly in the lungs, gastrointestinal tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Heart
The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenaline
Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration). It appears as a white microcrystalline granule. Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. It plays an essential role in the fight-or-flight response by increasing blood flow to muscles, heart output by acting on the SA node, pupil dilation response, and blood sugar level. It does this by binding to alpha and beta receptors. It is found in many animals, including humans, and some single-celled organisms. It has also been isolated from the plant ''Scoparia dulcis'' found in Northern Vietnam. Medical uses As a medication, it is used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Inhaled adrenaline may be used to improve the symptoms of croup. It may also be used for asthma when other treatments are not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Web Of Stories
Web of Stories is an online collection of thousands of autobiographical video-stories. Web of Stories, originally known as Science Archive, was set up to record the life stories of scientists. When it expanded to include the lives of authors, movie makers, artists and others, it was renamed Peoples Archive, finally evolving to become Web of Stories in 2008. The website features the video recordings of a broad range of the acknowledged leaders of our time telling their life stories. People recorded include: biologists Francis Crick and James Watson, physicist John Wheeler, neurologist Oliver Sacks, film editor Walter Murch, and authors Doris Lessing and Philip Roth, who are included among the 16 Nobel Prize winners, 19 Fellows of the Royal Society, 4 Pulitzer Prize winners, and 3 Academy Award winners. Web of Stories is based in London. References External linksWeb of Stories*Kathy M.Y. Pyon"Best of the Web" Los Angeles Times, October 10, 2012 (archived version at the Wayba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George H
George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd President of the United States * George H. W. Bush, 41st President of the United States * George V, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1910-1936 * George VI, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1936-1952 * Prince George of Wales * George Papagheorghe also known as Jorge / GEØRGE * George, stage name of Giorgio Moroder * George Harrison, an English musician and singer-songwriter Places South Africa * George, Western Cape ** George Airport United States * George, Iowa * George, Missouri * George, Washington * George County, Mississippi * George Air Force Base, a former U.S. Air Force base located in California Characters * George (Peppa Pig), a 2- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gertrude B
Gertrude or Gertrud may refer to: Places In space *Gertrude (crater), a crater on Uranus's moon Titania *710 Gertrud, a minor planet Terrestrial placenames * Gertrude, Arkansas * Gertrude, Washington * Gertrude, West Virginia People *Gertrude (given name), a given name (including a list of people with the name) People with Gertrude as the full name: *Blessed Gertrude of Aldenberg (1227–1297), daughter of Saint Elizabeth of Thuringia and abbess near Trier * Gertrude of Austria (1226–1288), Duchess of Austria and Styria * Gertrude of Babenberg (c.1118–1150), Duchess of Bohemia *Gertrude of Baden (c.1160–1225), Margravine of Baden *Gertrude of Bavaria (died 1197), daughter of Henry the Lion, Queen consort of Denmark *Gertrude of Brunswick (c.1060–1117), Margravine of Frisia and Meissen * Gertrude of Comburg (died 1130), Queen consort of Germany *Gertrude of Dagsburg (died 1225), Duchess of Lorraine * Gertrude of Delft (died 1358), Dutch Beguine and mystic *Gertrude of Fla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
