Juniperonic Acid
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Juniperonic Acid
Juniperonic acid is a polyunsaturated fatty acid featuring a 20-carbon chain with four ''cis''-configured double bonds at positions 5, 11, 14, and 17. These structural traits categorize the compound as an omega-3 fatty acid, and it has drawn significant scientific attention due to its influence on regulating lipid membrane function and cell signaling processes. It is an isomer of eicosatetraenoic acid like the better known omega-6 fatty acid, arachidonic acid. History and natural occurrence The acid was isolated for the first time in 1963 on the leaves and fruits of ''Ginkgo biloba'' by JL Gellerman and H. Schlenk. It was then identified in the oils of other plants, especially conifers: ''Taxodium distichum'' (14.25%), ''Cupressus funebris'' (10.27%), Platycladus orientalis (9%), ''Taxus cuspidata'' (6.8%), etc.; in other flowering plants: ''Ephedra gerardianaii'' (19.2%), ''Caltha sp.'' (9.4%), ''Ephedra nevadensis'' (9.3%), and ''Ephedra przewalskii'' (8.8%), among others; and in ...
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Double Bond
In chemistry, a double bond is a covalent bond between two atoms involving four bonding electrons as opposed to two in a single bond. Double bonds occur most commonly between two carbon atoms, for example in alkenes. Many double bonds exist between two different elements: for example, in a carbonyl group between a carbon atom and an oxygen atom. Other common double bonds are found in azo compounds (N=N), imines (C=N), and sulfoxides (S=O). In a skeletal formula, a double bond is drawn as two parallel lines (=) between the two connected atoms; typographically, the equals sign is used for this. Double bonds were introduced in chemical notation by Russian chemist Alexander Butlerov. Double bonds involving carbon are stronger and shorter than single bonds. The bond order is two. Double bonds are also electron-rich, which makes them potentially more reactive in the presence of a strong electron acceptor (as in addition reactions of the halogens). File:Ethene structural.svg, ...
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Ephedra Nevadensis
''Ephedra nevadensis'', commonly known as Nevada ephedra, gray ephedra, Mormon tea and Nevada jointfir, is a species of gymnosperm native to dry areas of western North America. Its range extends west to California, east to Colorado, north to Oregon, and south to Baja California, including areas of the Great Basin, Colorado Plateau and desert Southwest. It is found in rocky and sandy soils, generally in areas without trees. It can be found in a variety of environments but predominately grows in desert climates. It serves as a non toxic grazing source to both wild and domestic live stock. It posses a various amount of medicinal properties that can be used in a domestic setting. Historically, it is known for its usage in Mormon communities as tea. A common misconception is that ''Ephedra nevadensis'' contains ephedrine, a known stimulant however this is not true. Ecology ''Ephedra nevadensis'' can grow across a vast variety of biomes including but not limited to shrub lands, ...
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Α-Linolenic Acid
α-Linolenic acid, also known as ''alpha''-linolenic acid (ALA) (from Greek ''alpha'' denoting "first" and ''linon'' meaning flax), is an ''n''−3, or omega-3, essential fatty acid. ALA is found in many seeds and oils, including flaxseed, walnuts, chia, hemp, and many common vegetable oils. In terms of its structure, it is named ''all''-''cis''-9,12,15-octadecatrienoic acid. In physiological literature, it is listed by its lipid number, 18:3 (''n''−3). It is a carboxylic acid with an 18-carbon chain and three '' cis'' double bonds. The first double bond is located at the third carbon from the methyl end of the fatty acid chain, known as the ''n'' end. Thus, α-linolenic acid is a polyunsaturated ''n''−3 (omega-3) fatty acid. It is a regioisomer of gamma-linolenic acid (GLA), an 18:3 (''n''−6) fatty acid (i.e., a polyunsaturated omega-6 fatty acid with three double bonds). Etymology The word ''linolenic'' is an irregular derivation from ''linoleic'', which itself ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence of effectiveness or logical mechanism of action. Some TCM ingredients Traditional Chinese medicine#Safety, are known to be toxic and cause disease, including cancer. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, Scholar-official, literati theory and Confucianism, Confucian philosophy, Chinese herbology, herbal remedies, Chinese food therapy, food, diet, exercise, medical specializations, and schools of thought. TCM as it exists today has been described as a largely 20th century invention. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selec ...
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Thuja
''Thuja'' ( ) is a genus of coniferous tree or shrub in the Cupressaceae (cypress family). There are five species in the genus, two native to North America and three native to eastern Asia. The genus is monophyletic and sister to ''Thujopsis''. Members are commonly known as arborvitaes (from the Latin term for 'tree of life'), thujas or cedars. Description ''Thuja'' are evergreen trees growing from tall, with stringy-textured reddish-brown Bark (botany), bark. The shoots are flat, with side shoots only in a single plane. The leaves are scale-like and long, except young seedlings in their first year, which have needle-like leaves. The scale leaves are arranged in alternating decussate pairs in four rows along the twigs. The male cones are small, inconspicuous, and are located at the tips of the twigs. The female conifer cone, cones start out similarly inconspicuous, but grow to about long at maturity when 6–8 months old; they have 6-12 overlapping, thin, leathery scales, each ...
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Scientific Reports
''Scientific Reports'' is a peer-reviewed open-access scientific mega journal published by Nature Portfolio, covering all areas of the natural sciences. The journal was established in 2011. The journal states that their aim is to assess solely the scientific validity of a submitted paper, rather than its perceived importance, significance, or impact. In September 2016, the journal became the largest in the world by number of articles, overtaking '' PLOS ONE''. Abstracting and indexing The journal is abstracted and indexed in the Chemical Abstracts Service, the Science Citation Index Expanded, and selectively in Index Medicus/MEDLINE/PubMed. According to the ''Journal Citation Reports'', the journal has a 2023 impact factor 3.8. Reviewing policy The ''Guide to Referees'' states that to be published, "a paper must be scientifically valid and technically sound in methodology and analysis", and reviewers have to ensure manuscripts "are not assessed based on their perceived impor ...
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Methylene Group
A methylene group is any part of a molecule that consists of two hydrogen atoms bound to a carbon Carbon () is a chemical element; it has chemical symbol, symbol C and atomic number 6. It is nonmetallic and tetravalence, tetravalent—meaning that its atoms are able to form up to four covalent bonds due to its valence shell exhibiting 4 ... atom, which is connected to the remainder of the molecule by two single bonds. The group may be represented as or , where the '>' denotes the two bonds. This stands in contrast to a situation where the carbon atom is bound to the rest of the molecule by a double bond, which is preferably called a methylidene group, represented . Formerly the methylene name was used for both isomers. The name “ methylene bridge“ can be used for the single-bonded isomer, to emphatically exclude methylidene. The distinction is often important, because the double bond is chemically different from two single bonds. The methylene group should be d ...
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Sciadonic Acid
Sciadonic acid, also known as eicosatrienoic acid, is a polyunsaturated fatty acid. In regard to its structure, sciadonic acid has 3 double bonds in the 5, 11, and 14 positions all of which are in the ''cis'' configuration. It is further classified as Δ5-fatty, and an omega-6 acid due to the methylene interrupted double bond at carbon-5 and a final double bond 6 carbons away from the methylene tail of the hydrocarbon. Sciadonic acid is a naturally occurring compound and has been found to play a role as a plant metabolite, commonly found in pine nut oil. Furthermore, there have been propositions of several health applications for sciadonic acid as an anti-inflammatory agent. Sharing close structural similarity to arachidonic acid, sciadonic acid acts as a replacement phospholipid in the corresponding biochemical pathways. Etymology and natural occurrence The root behind the nomenclature of sciadonic acid comes from its high abundance in the seed, leaves, and wood oils of the pla ...
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Pinolenic Acid
Pinolenic acid (often misspelled as pinoleic acid) is a fatty acid contained in Siberian Pine nuts, Korean Pine nuts and the seed In botany, a seed is a plant structure containing an embryo and stored nutrients in a protective coat called a ''testa''. More generally, the term "seed" means anything that can be Sowing, sown, which may include seed and husk or tuber. Seeds ...s and xylem of other pine ('' Pinus'') species. The highest percentage of pinolenic acid is found in Siberian pine nuts and the oil produced from them. Chemistry and biochemistry Pinolenic acid is formally designated as ''all-cis-5,9,12-18:3''. Some sources also use the term columbinic acid for this substance. But ''columbinic acid'' sometimes designates an E-Z isomer (''trans'',''cis'',''cis'' ''delta''-5,9,12/18:3) in the biologic literature. Pinolenic acid is an isomer of gamma-linolenic acid (GLA). GLA is an ω-6 essential fatty acid (EFA) but pinolenic acid is not. However, like the ...
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Taxoleic Acid
Taxoleic acid is a diunsaturated fatty acid composed of 18 carbon atoms with double bonds in the positions 5=6 and 9=10, both in ''cis''-configuration. Taxoleic acid is isomeric to linoleic acid. Natural occurrence The acid is present in the seed oils of conifers, such as ''Pinus nigra'' (≈47%), ''Taxus cuspidata'' (≈16.2%), ''Taxus baccata'' (≈12.2%), ''Cedrus libani'' (≈9.4%), ''Abies pinsapo'' (≈8.2%), ''Pinus pinaster'' (≈7.1%), ''Abies alba'' (≈6.2%), among others. It is found in conifers, along with other fatty acids ( juniperonic, pinolenic, coniferonic, sciadonic acid) that have a double bond in the position 5, separated by more than one methylene group from the next double bond. Biosynthesis Taxoleic acid is believed to be biosynthesized from oleic acid by the enzyme Δ5-desaturase. A similar enzyme capable of producing taxolenic acid was also isolated from the oomycete '' Pythium irregulare''. The biosynthesis of taxolenic acid and similar fatty acids ha ...
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Tetrahedron Letters
''Tetrahedron Letters'' is a weekly international journal for rapid publication of full original research papers in the field of organic chemistry. According to the ''Journal Citation Reports'', the journal has a 2022 impact factor of 1.8 Indexing ''Tetrahedron Letters'' is indexed in: References See also *''Tetrahedron In geometry, a tetrahedron (: tetrahedra or tetrahedrons), also known as a triangular pyramid, is a polyhedron composed of four triangular Face (geometry), faces, six straight Edge (geometry), edges, and four vertex (geometry), vertices. The tet ...'' *'' Tetrahedron: Asymmetry'' Chemistry journals Weekly journals Academic journals established in 1959 Elsevier academic journals {{chem-journal-stub ...
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Walter De Gruyter GmbH & Co KG
Walter de Gruyter GmbH, known as De Gruyter (), is a German scholarly publishing house specializing in academic literature. History The roots of the company go back to 1749 when Frederick the Great granted the Königliche Realschule in Berlin the royal privilege to open a bookstore and "to publish good and useful books". In 1800, the store was taken over by Georg Reimer (1776–1842), operating as the ''Reimer'sche Buchhandlung'' from 1817, while the school's press eventually became the ''Georg Reimer Verlag''. From 1816, Reimer used a representative palace at Wilhelmstraße 73 in Berlin for his family and the publishing house, whereby the wings contained his print shop and press. The building later served as the Palace of the Reich President. Born in Ruhrort in 1862, Walter de Gruyter took a position with Reimer Verlag in 1894. By 1897, at the age of 35, he had become sole proprietor of the hundred-year-old company then known for publishing the works of German romantics s ...
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