Joshua Lederberg
Joshua Lederberg (May 23, 1925 – February 2, 2008) was an American molecular biology, molecular biologist known for his work in microbial genetics, artificial intelligence, and the United States space program. He was 33 years old when he won the 1958 Nobel Prize in Physiology or Medicine for discovering that bacteria can mate and exchange genes (bacterial conjugation). He shared the prize with Edward Tatum and George Beadle, who won for their work with genetics. In addition to his contributions to biology, Lederberg did extensive research in artificial intelligence. This included work in the NASA experimental programs seeking life on Mars and the chemistry expert system Dendral. Early life and education Lederberg was born in Montclair, New Jersey, to a Jewish family, son of Esther Goldenbaum Schulman Lederberg and Rabbi Zvi Hirsch Lederberg, in 1925, and moved to Washington Heights, Manhattan as an infant. He had two younger brothers. Lederberg graduated from Stuyvesant High S ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is Carnegie Classification of Institutions of Higher Education, classified as a "Special Focus – Research Institution". Rockefeller is the oldest biomedical research institute in the United States. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue / Sutton Place, York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'', the ''Journal of Cell Biology'', and ''The Journal of General Physiology''. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Scienc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Medicine or Physiology, Chemistry, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2024, 115 Nobel Prizes in Physiology or Medicine have been awarded to 229 laureates, 216 men and 13 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucida ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Life On Mars
The possibility of life on Mars is a subject of interest in astrobiology due to the planet's proximity and similarities to Earth. To date, no conclusive evidence of past or present life has been found on Mars. Cumulative evidence suggests that during the ancient Noachian time period, the surface environment of Water on Mars, Mars had liquid water and may have been Planetary habitability, habitable for microorganisms, but habitable conditions do not necessarily indicate life. Scientific searches for evidence of life began in the 19th century and continue today via telescopic investigations and deployed probes, searching for water, chemical biosignatures in the soil and rocks at the planet's surface, and biomarker gases in the atmosphere. Mars is of particular interest for the study of the Abiogenesis, origins of life because of its similarity to the early Earth. This is especially true since Mars has a cold climate and lacks plate tectonics or continental drift, so it has remain ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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NASA
The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States's civil list of government space agencies, space program, aeronautics research and outer space, space research. National Aeronautics and Space Act, Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the American space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo program missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station (ISS) along with the Commercial Crew Program and oversees the development of the Orion (spacecraft), Orion spacecraft and the Sp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biology
Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and distribution of life. Central to biology are five fundamental themes: the cell (biology), cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability (homeostasis). Biology examines life across multiple biological organisation, levels of organization, from molecules and cells to organisms, populations, and ecosystems. Subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. Each of these fields applies a range of methods to investigate biological phenomena, including scientific method, observation, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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George Beadle
George Wells Beadle (October 22, 1903 – June 9, 1989) was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells. He served as the 7th president of the University of Chicago from 1961 to 1968. Beadle and Tatum's key experiments involved exposing the bread mold ''Neurospora crassa'' to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways. These experiments led them to propose a direct link between genes and enzymatic reactions, known as the One gene-one enzyme hypothesis. Education and early life George Wells Beadle was born in Wahoo, Nebraska. He was the son of Chauncey Elmer Beadle and Hattie Albro, who owned and operated a farm nearby. George was educated at the Wahoo High School and might himself have become a farmer if one o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Kevin Warwick
Kevin Warwick (born 9 February 1954) is an English engineer and Deputy Vice-Chancellor (Research) at Coventry University. He is known for his studies on direct interfaces between computer systems and the human nervous system, and has also done research concerning robotics. Biography Kevin Warwick was born in 1954 in Keresley, Coventry, England, and was raised in the nearby village of Ryton-on-Dunsmore, Warwickshire. His family attended a Methodist church but soon he began doubting the existence of God. He attended Lawrence Sheriff School in Rugby, Warwickshire, where he was a contemporary of actor Arthur Bostrom. He left school at the age of 16 to start an apprenticeship with British Telecom. In 1976, he was granted his first degree at Aston University, followed by a PhD degree and a research job at Imperial College London. He took up positions at Somerville College in Oxford, Newcastle University, the University of Warwick, and the University of Reading, before relocating ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bacterial Conjugation
Bacterial conjugation is the transfer of genetic material between Bacteria, bacterial cells by direct cell-to-cell contact or by a bridge-like connection between two cells. This takes place through a pilus. It is a parasexual cycle, parasexual mode of reproduction in bacteria. It is a mechanism of horizontal gene transfer as are Transformation (genetics), transformation and Transduction (genetics), transduction although these two other mechanisms do not involve cell-to-cell contact. Classical ''E. coli'' bacterial conjugation is often regarded as the bacterial equivalent of sexual reproduction or mating, since it involves the exchange of genetic material. However, it is not sexual reproduction, since no exchange of gamete occurs, and indeed no biogenesis, generation of a new organism: instead, an existing organism is transformed. During classical ''E. coli'' conjugation, the ''donor'' cell provides a conjugative or mobilizable genetic element that is most often a plasmid or trans ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, suc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Artificial Intelligence
Artificial intelligence (AI) is the capability of computer, computational systems to perform tasks typically associated with human intelligence, such as learning, reasoning, problem-solving, perception, and decision-making. It is a field of research in computer science that develops and studies methods and software that enable machines to machine perception, perceive their environment and use machine learning, learning and intelligence to take actions that maximize their chances of achieving defined goals. High-profile applications of AI include advanced web search engines (e.g., Google Search); recommendation systems (used by YouTube, Amazon (company), Amazon, and Netflix); virtual assistants (e.g., Google Assistant, Siri, and Amazon Alexa, Alexa); autonomous vehicles (e.g., Waymo); Generative artificial intelligence, generative and Computational creativity, creative tools (e.g., ChatGPT and AI art); and Superintelligence, superhuman play and analysis in strategy games (e.g., ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biographical Memoirs Of Fellows Of The Royal Society
The ''Biographical Memoirs of Fellows of the Royal Society'' is an academic journal on the history of science published annually by the Royal Society. It publishes obituaries of Fellows of the Royal Society. It was established in 1932 as ''Obituary Notices of Fellows of the Royal Society'' and obtained its current title in 1955, with volume numbering restarting at 1. Prior to 1932, obituaries were published in the '' Proceedings of the Royal Society''. The memoirs are a significant historical record and most include a full bibliography of works by the subjects. The memoirs are often written by a scientist of the next generation, often one of the subject's own former students, or a close colleague. In many cases the author is also a Fellow. Notable biographies published in this journal include Albert Einstein, Alan Turing, Bertrand Russell Bertrand Arthur William Russell, 3rd Earl Russell, (18 May 1872 – 2 February 1970) was a British philosopher, logician, mathematic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |