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Horizontal Neurons
Horizontal cells are the laterally interconnecting neurons having cell bodies in the inner nuclear layer of the retina of vertebrate eyes. They help integrate and regulate the input from multiple photoreceptor cells. Among their functions, horizontal cells are believed to be responsible for increasing contrast via lateral inhibition and adapting both to bright and dim light conditions. Horizontal cells provide inhibitory feedback to rod and cone photoreceptors. They are thought to be important for the antagonistic center-surround property of the receptive fields of many types of retinal ganglion cells. Other retinal neurons include photoreceptor cells, bipolar cells, amacrine cells, and retinal ganglion cells. Structure Depending on the species, there are typically one or two classes of horizontal cells, with a third type sometimes proposed. Horizontal cells span across photoreceptors and summate inputs before synapsing onto photoreceptor cells. Horizontal cells may also sy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retina
The retina (; or retinas) is the innermost, photosensitivity, light-sensitive layer of tissue (biology), tissue of the eye of most vertebrates and some Mollusca, molluscs. The optics of the eye create a focus (optics), focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception. The retina serves a function which is in many ways analogous to that of the photographic film, film or image sensor in a camera. The neural retina consists of several layers of neurons interconnected by Chemical synapse, synapses and is supported by an outer layer of pigmented epithelial cells. The primary light-sensing cells in the retina are the photoreceptor cells, which are of two types: rod cell, rods and cone cell, cones. Rods function mainly in dim light and provide monochromatic vision. Cones function in well-lit conditions and are responsible fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Starburst Amacrine Cell
Starburst amacrine cells are a type of amacrine cells found in the retina. These interneurons are notable for co-releasing acetylcholine and GABA. See also List of distinct cell types in the adult human body The list of human cell types provides an enumeration and description of the various specialized cells found within the human body, highlighting their distinct functions, characteristics, and contributions to overall physiological processes. Cell ... References External links Starburst Amacrine Cellon Eyewire.org. Neurons {{neuroanatomy-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Eye Anatomy
Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are great apes characterized by their hairlessness, bipedalism, and high intelligence. Humans have large brains, enabling more advanced cognitive skills that facilitate successful adaptation to varied environments, development of sophisticated tools, and formation of complex social structures and civilizations. Humans are highly social, with individual humans tending to belong to a multi-layered network of distinct social groups — from families and peer groups to corporations and political states. As such, social interactions between humans have established a wide variety of values, social norms, languages, and traditions (collectively termed institutions), each of which bolsters human society. Humans are also highly curious: the desire to understand and influence phenomena has motivated humanity's development ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gunnar Svaetichin
Gunnar Nils Toivo Svaetichin (13 January 1915 – 23 March 1981) was a Swedish people, Swedish-Finnish people, Finnish-Venezuelan people, Venezuelan physiology, physiologist who, in 1956, showed by examining the external layers of fish retinas that Electroretinography, electroretinograms display particular sensitivity to three different groups of wavelengths in the areas of blue, green and red. This provided the first biological demonstration in support of the Young–Helmholtz theory, Young-Helmholtz trichromatic theory. He also gave name to the S-potential, which was the first experimental evidence that Opponent process, opponency existed in the visual system. Born in Finland, he moved to Sweden in 1948, and from 1955 until his death, he worked as a researcher in Venezuela. Early life and family He was born in 1915 in Karis, Finland, the son of the engineering surveyor Volmar Svaetichin and his wife Ellen (born Nordstrom). Education After attending schools in Karis and Helsinki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Distinct Cell Types In The Adult Human Body
The list of human cell types provides an enumeration and description of the various specialized cells found within the human body, highlighting their distinct functions, characteristics, and contributions to overall physiological processes. Cells may be classified by their physiological function, histology (microscopic anatomy), lineage, or gene expression. Total number of cells The adult human body is estimated to contain about 30 trillion (3×1013) human cells, with the number varying between 20 and 100 trillion depending on factors such as sex, age, and weight. Additionally, there are approximately an equal number of bacterial cells. The exact count of human cells has not yet been empirically measured in its entirety and is estimated using different approaches based on smaller samples of empirical observation. It is generally assumed that these cells share features with each other and thus may be organized as belonging to a smaller number of types. Classification ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amacrine Cells
In the anatomy of the eye, amacrine cells are interneurons in the retina. They are named , because of their short neuronal processes. Amacrine cells are inhibitory neurons which project their dendritic arbors onto the inner plexiform layer (IPL). They interact with retinal ganglion cells and bipolar cells. Structure Amacrine cells operate at the inner plexiform layer (IPL), the second synaptic retinal layer where bipolar cells and retinal ganglion cells form synapses. There are at least 33 different subtypes of amacrine cells based just on their dendrite morphology and stratification. Like horizontal cells, amacrine cells work laterally, but whereas horizontal cells are connected to the output of rod and cone cells, amacrine cells affect the output from bipolar cells, and are often more specialized. Each type of amacrine cell releases one or several neurotransmitters where it connects with other cells. They are often classified by the width of their field of connection ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bipolar Cell Of The Retina
As a part of the retina, bipolar cells exist between photoreceptors (rod cells and cone cells) and ganglion cells. They act, directly or indirectly, to transmit signals from the photoreceptors to the ganglion cells. Structure Bipolar cells are so-named as they have a central body from which two sets of processes arise. They can synapse with either rods or cones (rod/cone mixed input BCs have been found in teleost fish but not mammals), and they also accept synapses from horizontal cells. The bipolar cells then transmit the signals from the photoreceptors or the horizontal cells, and pass it on to the ganglion cells directly or indirectly (via amacrine cells). Unlike most neurons, bipolar cells communicate via graded potentials, rather than action potentials. Function Bipolar cells receive synaptic input from either rods or cones, or both rods and cones, though they are generally designated rod bipolar or cone bipolar cells. There are roughly 10 distinct forms of cone bipolar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photoreceptor Cell
A photoreceptor cell is a specialized type of neuroepithelial cell found in the retina that is capable of visual phototransduction. The great biological importance of photoreceptors is that they convert light (visible electromagnetic radiation) into signals that can stimulate biological processes. To be more specific, photoreceptor proteins in the cell absorb photons, triggering a change in the cell's membrane potential. There are currently three known types of photoreceptor cells in mammalian eyes: rod cell, rods, cone cell, cones, and intrinsically photosensitive retinal ganglion cells. The two classic photoreceptor cells are rods and cones, each contributing information used by the visual system to form an image of the environment, Visual perception, sight. Rods primarily mediate scotopic vision (dim conditions) whereas cones primarily mediate photopic vision (bright conditions), but the processes in each that supports phototransduction is similar. The intrinsically photosen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Center-surround Antagonism
Center-surround antagonism refers to antagonistic interactions between center and surround regions of the receptive fields of photoreceptor cells in the retina. Center surround antagonism enables edge detection and contrast enhancement within the visual cortex The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalam .... References * Signal transduction {{eye-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma-Aminobutyric Acid
GABA (gamma-aminobutyric acid, γ-aminobutyric acid) is the chief inhibitory neurotransmitter in the developmentally mature mammalian central nervous system. Its principal role is reducing neuronal excitability throughout the nervous system. GABA is sold as a dietary supplement in many countries. It has been traditionally thought that exogenous GABA (i.e., taken as a supplement) does not cross the blood–brain barrier, but data obtained from more recent research (2010s) in rats describes the notion as being unclear. The carboxylate form of GABA is γ-aminobutyrate. Function Neurotransmitter Two general classes of GABA receptor are known: * GABAA receptor, GABAA in which the receptor is part of a ligand-gated ion channel complex * GABAB receptor, GABAB metabotropic receptors, which are G protein-coupled receptors that open or close ion channels via intermediaries (G proteins) Neurons that produce GABA as their output are called GABAergic neurons, and have chiefly inhibito ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gap Junction
Gap junctions are membrane channels between adjacent cells that allow the direct exchange of cytoplasmic substances, such small molecules, substrates, and metabolites. Gap junctions were first described as ''close appositions'' alongside tight junctions, however, electron microscopy studies in 1967 led to gap junctions being named as such to be distinguished from tight junctions. They bridge a 2-4 nm gap between cell membranes. Gap junctions use protein complexes known as connexons, composed of connexin proteins to connect one cell to another. Gap junction proteins include the more than 26 types of connexin, as well as at least 12 non-connexin components that make up the gap junction complex or ''nexus,'' including the tight junction protein ZO-1—a protein that holds membrane content together and adds structural clarity to a cell, sodium channels, and aquaporin. More gap junction proteins have become known due to the development of next-generation sequencing. Connexins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Negative Feedback
Negative feedback (or balancing feedback) occurs when some function (Mathematics), function of the output of a system, process, or mechanism is feedback, fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances. Whereas positive feedback tends to instability via exponential growth, oscillation or chaos theory, chaotic behavior, negative feedback generally promotes stability. Negative feedback tends to promote a settling to List of types of equilibrium, equilibrium, and reduces the effects of perturbations. Negative feedback loops in which just the right amount of correction is applied with optimum timing, can be very stable, accurate, and responsive. Negative feedback is widely used in Mechanical engineering, mechanical and electronic engineering, and it is observed in many other fields including biology, chemistry and economics. General negative feedback systems are studied in Control engin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
