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H. R. Cox
Herald Rea Cox (1907–1986) was an American bacteriologist. The bacterial family Coxiellaceae and the genus '' Coxiella'', which include the organism that causes Q fever, are named after him. Biography Born in Terre Haute, Indiana, he graduated from Indiana State Normal School, now Indiana State University, in 1928 before obtaining his doctorate from the Johns Hopkins Bloomberg School of Public Health. In the 1930s, Cox joined the U.S. Public Health Service as Principal Bacteriologist at the Rocky Mountain Laboratory in Hamilton, Montana. While there, he studied rickettsia, a group of organisms that causes Rocky Mountain spotted fever and typhus. In 1938, he discovered that rickettsia could be grown in fertile egg membranes, which led to the development of vaccines to combat Rocky Mountain spotted fever and vaccines for several strains of typhus. The family Coxiellaceae and the genus Coxiella, which contain the organism that causes Q fever, are named for Cox. In 1942, Cox beca ...
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Terre Haute, Indiana
Terre Haute ( ) is a city in Vigo County, Indiana, United States, and its county seat. As of the 2020 United States census, 2020 census, the city had a population of 58,389 and Terre Haute metropolitan area, its metropolitan area had a population of 168,716. Located along the Wabash River about east of the state border with Illinois, Terre Haute is one of the largest cities in the Wabash Valley and is known as the Queen City of the Wabash. The city is home to multiple higher-education institutions, including Indiana State University, Rose-Hulman Institute of Technology, and Ivy Tech Community College of Indiana. It also contains the United States Penitentiary, Terre Haute, which houses the US federal death row. History Terre Haute's name is derived from the French phrase ''terre haute'' (pronounced in French), meaning "highland". It was named by French-Canadian explorers and fur trappers to the area in the early 18th century to describe the unique location above the Wabash Ri ...
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Rickettsia
''Rickettsia'' is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long). The genus was named after Howard Taylor Ricketts in honor of his pioneering work on tick-borne spotted fever. Properly, ''Rickettsia'' is the name of a single genus, but the informal term "rickettsia", plural "rickettsias," usually not capitalised, commonly applies to any members of the order Rickettsiales. Being obligate intracellular bacteria, rickettsias depend on entry, growth, and replication within the cytoplasm of living eukaryotic host cells (typically endothelial cells). Accordingly, ''Rickettsia'' species cannot grow in artificial nutrient culture; they must be grown either in tissue or embryo cultures. Mostly chicken embryos are used, following a method developed by Ernest William Goodpasture and his colleagues at Vanderbilt University i ...
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Indiana State University Alumni
Indiana ( ) is a state in the Midwestern region of the United States. It borders Lake Michigan to the northwest, Michigan to the north and northeast, Ohio to the east, the Ohio River and Kentucky to the south and southeast, and the Wabash River and Illinois to the west. Nicknamed "the Hoosier State", Indiana is the 38th-largest by area and the 17th-most populous of the 50 states. Its capital and largest city is Indianapolis. Indiana was admitted to the Union as the 19th state on December 11, 1816. Indigenous resistance to American settlement was broken with defeat of the Tecumseh's confederacy in 1813. The new settlers were primarily Americans of British ancestry from the eastern seaboard and the Upland South, and Germans. After the Civil War, in which the state fought for the Union, natural gas attracted heavy industry and new European immigrants to its northern counties. In the first half of the 20th century, northern and central sections experienced a boom in good ...
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1986 Deaths
The year 1986 was designated as the International Year of Peace by the United Nations. Events January * January 1 ** Aruba gains increased autonomy from the Netherlands by separating from the Netherlands Antilles. ** Spain and Portugal enter the European Community, which becomes the European Union in 1993. * January 11 – The Sir Leo Hielscher Bridges, Gateway Bridge in Brisbane, Australia, at this time the world's longest prestressed concrete free-cantilever bridge, is opened. * January 13–January 24, 24 – South Yemen Civil War. * January 20 – The United Kingdom and France announce plans to construct the Channel Tunnel. * January 24 – The Voyager 2 space probe makes its first encounter with Uranus. * January 25 – Yoweri Museveni's National Resistance Army Rebel group takes over Uganda after leading a Ugandan Bush War, five-year guerrilla war in which up to half a million people are believed to have been killed. They will later use January 26 as the official date ...
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1907 Births
Events January * January 14 – 1907 Kingston earthquake: A 6.5 Mw earthquake in Kingston, Jamaica, kills between 800 and 1,000. February * February 9 – The " Mud March", the first large procession organised by The National Union of Women's Suffrage Societies ( NUWSS), takes place in London. * February 11 – The French warship ''Jean Bart'' sinks off the coast of Morocco. * February 12 – The steamship ''Larchmont'' collides with the ''Harry Hamilton'' in Long Island Sound; 183 lives are lost. * February 16 – SKF, a worldwide mechanical parts manufacturing brand (mainly, bearings and seals), is founded in Gothenburg, Sweden. * February 21 – The English mail steamship ''Berlin'' is wrecked off the Hook of Holland; 142 lives are lost. * February 24 – The Austrian Lloyd steamship ''Imperatrix'', from Trieste to Bombay, is wrecked on Cape of Crete and sinks; 137 lives are lost. March * March ** The steamship ''Congo'' collide ...
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Hilary Koprowski
Hilary Koprowski (5 December 191611 April 2013) was a Polish virologist and immunologist active in the United States who demonstrated the world's first effective live polio vaccine. He authored or co-authored over 875 scientific papers and co-edited several scientific journals. Koprowski received many academic honors and national decorations, including the Belgian Order of the Lion, the French Order of Merit and Legion of Honour, Finland's Order of the Lion, and the Order of Merit of the Republic of Poland. Koprowski was the target of accusations in the press related to the " oral polio vaccine AIDS hypothesis", which posited that the AIDS pandemic originated from live polio vaccines developed by Koprowski in the Belgian Congo. This hypothesis was challenged on numerous grounds, and scientists largely rejected it. Life Hilary Koprowski was born in Warsaw to an educated, assimilated Jewish family. His parents met in 1906 when Paweł Koprowski (1882–1957) was serving in t ...
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Albert Sabin
Albert Bruce Sabin ( ; born Abram Saperstejn; August 26, 1906 – March 3, 1993) was a Polish-American medical researcher, best known for developing the oral polio vaccine, which has played a key role in nearly Poliomyelitis eradication, eradicating the disease. In 1969–72, he served as the president of the Weizmann Institute of Science in Israel. Biography Abram Saperstejn was born in Białystok, Russian Empire (before and since 1918 in Poland), to History of the Jews in Poland, Polish-Jewish parents, Jacob Saperstejn and Tillie Krugman. In 1921, he emigrated with his family on the SS Lapland, SS ''Lapland'' which sailed from Antwerp to the Port of New York and New Jersey, Port of New York. In 1930, he became a naturalized citizen of the United States and changed his name to Albert Bruce Sabin. He graduated from high school in Paterson, New Jersey. Sabin began university in a dentistry program, but was interested in virology and changed majors. He received a bachelor's deg ...
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John Franklin Enders
John Franklin Enders (February 10, 1897 – September 8, 1985) was an American biomedical scientist and Nobel Laureate. Enders has been called "The Father of Modern Vaccines." Life and education Enders was born in West Hartford, Connecticut on February 10, 1897. His father, John Ostrom Enders, was CEO of the Hartford National Bank and left him a fortune of $19 million upon his death. He attended the Noah Webster School in Hartford, and St. Paul's School in Concord, New Hampshire. After attending Yale University a short time, he joined the United States Army Air Corps in 1918 as a flight instructor and a lieutenant. After returning from World War I, he graduated from Yale, where he was a member of Scroll and Key as well as Delta Kappa Epsilon. He went into real estate in 1922, and tried several careers before choosing the biomedical field with a focus on infectious diseases, gaining a PhD at Harvard in 1930. He later joined the faculty at Children's Hospital Boston. Enders die ...
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Jonas Salk
Jonas Edward Salk (; born Jonas Salk; October 28, 1914June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine. In 1947, Salk accepted a professorship at the University of Pittsburgh School of Medicine, where he undertook a project beginning in 1948 to determine the number of different types of poliovirus. For the next seven years, Salk devoted himself to developing a vaccine against polio. Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution. The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine, but since Salk's techniques were not novel, their patent attorney said, ...
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Polio
Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia. These symptoms usually pass within one or two weeks. A less common symptom is permanent Flaccid paralysis, paralysis, and possible death in extreme cases.. Years after recovery, post-polio syndrome may occur, with a slow development of muscle weakness similar to what the person had during the initial infection. Polio occurs naturally only in humans. It is highly infectious, and is spread from person to person either through fecal–oral route, fecal–oral transmission (e.g. poor hygiene, or by ingestion of food or water contaminated by human feces), or via the oral–oral route. Those who are infected may spread the disease for up to six weeks even if no symptoms are pre ...
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Typhus
Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. Common symptoms include fever, headache, and a rash. Typically these begin one to two weeks after exposure. The diseases are caused by specific types of bacterial infection. Epidemic typhus is caused by '' Rickettsia prowazekii'' spread by body lice, scrub typhus is caused by '' Orientia tsutsugamushi'' spread by chiggers, and murine typhus is caused by '' Rickettsia typhi'' spread by fleas. Vaccines have been developed, but none is commercially available. Prevention is achieved by reducing exposure to the organisms that spread the disease. Treatment is with the antibiotic doxycycline. Epidemic typhus generally occurs in outbreaks when poor sanitary conditions and crowding are present. While once common, it is now rare. Scrub typhus occurs in Southeast Asia, Japan, and northern Australia. Murine typhus occurs in tropical and subtropi ...
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Rocky Mountain Spotted Fever
Rocky Mountain spotted fever (RMSF) is a bacterial disease spread by ticks. It typically begins with a fever and headache, which is followed a few days later with the development of a rash. The rash is generally Petechial rash, made up of small spots of bleeding and starts on the wrists and ankles. Other symptoms may include muscle pains and vomiting. Long-term complications following recovery may include hearing loss or loss of part of an arm or leg. The disease is caused by ''Rickettsia rickettsii'', a type of bacterium that is primarily spread to humans by American dog ticks, Rocky Mountain wood ticks, and brown dog ticks. Rarely the disease is spread by blood transfusions. Diagnosis in the early stages is difficult. A number of laboratory tests can confirm the diagnosis but treatment should be begun based on symptoms. It is within a group known as spotted fever rickettsiosis, together with Rickettsia parkeri rickettsiosis, ''Rickettsia parkeri'' rickettsiosis, Pacific Coast t ...
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