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Genetic Matchmaking
Genetic matchmaking is the idea of matching couples for romantic relationships based on their biological compatibility. The initial idea was conceptualized by Claus Wedekind through his "sweaty t-shirt" experiment.Wedekind, C., et al. "MHC-Dependent Mate Preferences in Humans." Proceedings.Biological sciences / The Royal Society 260.1359 (1995): 245-9. Males were asked to wear T-shirts for two consecutive nights, and then females were asked to smell the T-shirts and rate the body odors for attractiveness. Human body odor has been associated with the human leukocyte antigens (HLA) genomic region. They discovered that females were attracted to men who had dissimilar HLA alleles from them. Furthermore, these females reported that the body odors of HLA-dissimilar males reminded them of their current partners or ex-partners providing further evidence of biological compatibility. Research Following research done by Dr. Wedekind, several studies found corroborating evidence for bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Claus Wedekind
Claus Wedekind is a Swiss biological researcher notable for his 1995 study that determined a major histocompatibility complex (MHC) dependent mate preference in humans. This study is often known as the "sweaty T-shirt study". In it, men each wore the same T-shirt for two days. The shirts were then put into identical boxes. Various women were asked to smell the shirts, and to indicate to which shirts they were most sexually attracted. The results showed that women were most attracted to men with an MHC most dissimilar from their own. MHC and sexual selection It has been suggested that MHC plays a role in the selection of potential mates, via olfaction. MHC genes make molecules that enable the immune system to recognise invaders; generally, the more diverse the MHC genes of the parents, the stronger the immune system of the offspring. It would obviously be beneficial, therefore, to have a system of recognizing individuals with different MHC genes and preferentially selecting the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Leukocyte Antigens
The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for the regulation of the immune system. The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. Mutations in HLA genes may be linked to autoimmune disease such as type I diabetes, and celiac disease. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6, p-arm at 21.3. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as ''antigens'', as a result of their historic discovery as factors in organ transplants. HLAs corresponding to MHC class I ( A, B, and C), all of which are the HLA Class1 group, present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hutterites
Hutterites (german: link=no, Hutterer), also called Hutterian Brethren (German: ), are a communal ethnoreligious branch of Anabaptists, who, like the Amish and Mennonites, trace their roots to the Radical Reformation of the early 16th century and have formed intentional communities. The founder of the Hutterites, Jacob Hutter, "established the Hutterite colonies on the basis of the Schleitheim Confession, a classic Anabaptist statement of faith" of 1527, and the first communes were formed in 1528. Since the death of Hutter in 1536, the beliefs of the Hutterites, especially those espousing a community of goods and nonresistance, have resulted in hundreds of years of diaspora in many countries. The Hutterites embarked on a series of migrations through central and eastern Europe. Nearly extinct by the 18th century, they migrated to Russia in 1770 and about a hundred years later to North America. Over the course of 140 years, their population living in community of goods recove ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International HapMap Project
The International HapMap Project was an organization that aimed to develop a haplotype map (HapMap) of the human genome, to describe the common patterns of human genetic variation. HapMap is used to find genetic variants affecting health, disease and responses to drugs and environmental factors. The information produced by the project is made freely available for research. The International HapMap Project is a collaboration among researchers at academic centers, non-profit biomedical research groups and private companies in Canada, China (including Hong Kong), Japan, Nigeria, the United Kingdom, and the United States. It officially started with a meeting on October 27 to 29, 2002, and was expected to take about three years. It comprises two phases; the complete data obtained in Phase I were published on 27 October 2005. The analysis of the Phase II dataset was published in October 2007. The Phase III dataset was released in spring 2009 and the publication presenting the final res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation tends to exist within any given population as a result of genetic mutation and recombination. Evolution occurs when evolutionary processes such as natural selection (including sexual selection) and genetic drift act on this variation, resulting in certain characteristics becoming more common or more rare within a population. The evolutionary pressures that determine whether a characteristic is common or rare within a population constantly change, resulting in a change in heritable characteristics arising over successive generations. It is this process of evolution that has given rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. The theory of evolut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
